Unmasking the Silent Threat: Periodontal Health’s Impact on COPD Severity and Hospitalization DOI Open Access
Anitha Subbappa, K Lokesh, Sindaghatta Krishnarao Chaya

и другие.

Journal of Personalized Medicine, Год журнала: 2023, Номер 13(12), С. 1714 - 1714

Опубликована: Дек. 15, 2023

Objective: This study investigated the relationship between chronic obstructive pulmonary disease (COPD) and periodontitis, focusing on how periodontal health impacts COPD airflow limitation, exacerbations, hospitalization. Background: Periodontitis, a multifactorial inflammatory disease, is characterized by destruction of tooth-supporting structures, while global disorder with high mortality. Methods: A total 199 patients aged over 40 years underwent lung function tests (spirometry), 6 min walk test, St George’s Respiratory Questionnaire-COPD (SGRQ-C) to assess health. Periodontal indices such as probing depth (PD), clinical attachment loss (CAL), plaque index (PI) were assessed. Results: We found significant negative correlation severity (lower FEV1, FVC, FEV1/FVC ratio) after adjusting for smoking. Likewise, parameters (PPD, PI, CAL) exhibited correlations function. These independently associated limitation severity, exacerbations frequency, prior-year Linear regression indicated that each unit increase in PPD, CAL corresponded estimated increases GOLD grading (0.288, 0.718, 0.193, respectively) number (0.115, 0.041, 0.109, respectively). In logistic regression, adjusted odds ratios (ORs) 1.29 (95%CI: 1.03–1.62), 3.04 1.28–7.2), 1.26 1.06–1.49), respectively, hospitalization previous year. Conclusion: Periodontitis exacerbation, hospitalization, PI being most clinically relevant factor. Dentists physicians should monitor awareness among maintain oral hygiene prevention diseases mitigate its effect progression.

Язык: Английский

Association between periodontal disease and chronic obstructive pulmonary disease DOI Creative Commons

Peiya Lin,

Anhao Liu, Yosuke Tsuchiya

и другие.

Japanese Dental Science Review, Год журнала: 2023, Номер 59, С. 389 - 402

Опубликована: Ноя. 7, 2023

Chronic obstructive pulmonary disease (COPD) and periodontal are chronic inflammatory conditions that significantly affect an individual's overall health well-being. Generally, the prevalence of periodontitis is higher in patients with COPD than those without COPD, which may partly be attributed to common risk factors such as smoking, respiratory infections, inflammation. In particular, exacerbate progression further deteriorate system by promoting responses bacterial infections. Immunocytes, including neutrophils, microorganisms Fusobacterium nucleatum originating from oral biofilms believed crucial influencing COPD. Furthermore, potential benefits treating outcomes have been investigated. Although relationship between has preliminarily studied, there currently a lack large-scale clinical studies validate this association. addition examinations, investigating biomarkers microbiology contribute explore underlying mechanisms involved management these conditions. This review aims better understanding basic research aspects periodontitis, allowing for therapeutic approaches interdisciplinary strategies.

Язык: Английский

Процитировано

7
Unmasking the Silent Threat: Periodontal Health’s Impact on COPD Severity and Hospitalization DOI Open Access
Anitha Subbappa, K Lokesh, Sindaghatta Krishnarao Chaya

и другие.

Journal of Personalized Medicine, Год журнала: 2023, Номер 13(12), С. 1714 - 1714

Опубликована: Дек. 15, 2023

Objective: This study investigated the relationship between chronic obstructive pulmonary disease (COPD) and periodontitis, focusing on how periodontal health impacts COPD airflow limitation, exacerbations, hospitalization. Background: Periodontitis, a multifactorial inflammatory disease, is characterized by destruction of tooth-supporting structures, while global disorder with high mortality. Methods: A total 199 patients aged over 40 years underwent lung function tests (spirometry), 6 min walk test, St George’s Respiratory Questionnaire-COPD (SGRQ-C) to assess health. Periodontal indices such as probing depth (PD), clinical attachment loss (CAL), plaque index (PI) were assessed. Results: We found significant negative correlation severity (lower FEV1, FVC, FEV1/FVC ratio) after adjusting for smoking. Likewise, parameters (PPD, PI, CAL) exhibited correlations function. These independently associated limitation severity, exacerbations frequency, prior-year Linear regression indicated that each unit increase in PPD, CAL corresponded estimated increases GOLD grading (0.288, 0.718, 0.193, respectively) number (0.115, 0.041, 0.109, respectively). In logistic regression, adjusted odds ratios (ORs) 1.29 (95%CI: 1.03–1.62), 3.04 1.28–7.2), 1.26 1.06–1.49), respectively, hospitalization previous year. Conclusion: Periodontitis exacerbation, hospitalization, PI being most clinically relevant factor. Dentists physicians should monitor awareness among maintain oral hygiene prevention diseases mitigate its effect progression.

Язык: Английский

Процитировано

2