Опубликована: Янв. 1, 2024
Язык: Английский
Environmental Epidemiology, Год журнала: 2024, Номер 8(3), С. e307 - e307
Опубликована: Апрель 16, 2024
Background: Continuous ambient air quality monitoring in Kenya has been limited, resulting a sparse data base on the health impacts of pollution for country. We have operated centrally located monitor Nairobi measuring fine particulate matter (PM 2.5 ), pollutant that demonstrated impact health. Here, we describe temporal levels and trends PM evaluate associated implications. Methods: used reference sensor, beta attenuation (BAM-1022), to measure hourly concentrations over 3-year period (21 August 2019 20 2022). used, at minimum, 75% daily concentration represent 24-hour given calendar day. To estimate deaths attributable pollution, World Health Organization (WHO) AirQ+ tool with input as data, local mortality statistics, population sizes. Results: The (24-hour) mean (±SEM) was 19. 2 ± 0.6 (µg/m 3 ). Pollutant were lowest 03:00 and, peaked 20:00. Sundays had concentrations, which increased Mondays remained high through Saturdays. By season, April highest August. annual 18.4 7.1 estimated lead between 400 1,400 premature city’s 2021 hence contributing 5%–8% 17,432 adult excluding accidents when referenced WHO recommended guideline thresholds 5 µg/m . Conclusion: Fine showed daily, day-of-week, seasonal fluctuations consistent anthropogenic source mix, particularly from motor vehicles. long-term exposure 3.7 times higher than substantial burden deaths. An updated regulation targeting measures reduce vehicular emissions is recommended.
Язык: Английский
Процитировано
6
ACS Omega, Год журнала: 2024, Номер 9(8), С. 8615 - 8631
Опубликована: Фев. 15, 2024
Pollution is ubiquitous, and much of it anthropogenic in nature, which a severe risk factor not only for respiratory infections or asthma sufferers but also Alzheimer's disease, has received lot attention recently. This Review aims to investigate the primary environmental factors their profound impact on disease. It underscores pivotal role multidimensional imaging early disease identification prevention. Conducting comprehensive review, we delved into plethora literature sources available through esteemed databases, including Science Direct, Google Scholar, Scopus, Cochrane, PubMed. Our search strategy incorporated keywords such as "Alzheimer Disease", "Alzheimer's", "Dementia", "Oxidative Stress", "Phytotherapy" conjunction with "Criteria Pollutants", "Imaging", "Pathology", "Particulate Matter". result complex biological exacerbated by infiltration airborne particles gases that surreptitiously breach nasal defenses traverse brain, akin Trojan horse. Various modalities noninvasive techniques have been harnessed identify progression its incipient stages. However, each approach possesses inherent limitations, prompting exploration unified technique under single umbrella. Multidimensional stands linchpin detecting forestalling relentless march Given intricate etiology condition, identifying prospective candidate may take decades, rendering development multimodal an imperative. research pressing need recognize chronic ramifications invisible particulate matter advance our understanding insidious contribute
Язык: Английский
Процитировано
3
International Journal of Biometeorology, Год журнала: 2024, Номер 68(8), С. 1689 - 1698
Опубликована: Май 14, 2024
Язык: Английский
Процитировано
3
International Journal of COPD, Год журнала: 2025, Номер Volume 20, С. 735 - 751
Опубликована: Март 1, 2025
Pandemic-era associations between air pollutant exposures and exacerbations of chronic obstructive pulmonary disease (COPD) are under-explored. Given the considerable observed pandemic-era fluctuations, these were investigated along with possible individual-level risk factors. Participants spirometry-confirmed COPD from Canadian Cohort Obstructive Lung Disease (CanCOLD) included, data collected before ("pre-pandemic") during ("pandemic") COVID-19 pandemic. Nitrogen dioxide (NO2), fine particulate matter (PM2.5), ground-level ozone (O3), total oxidant (Ox) weather obtained national databases. Associations each "symptom-based" (increased dyspnea or sputum volume/purulence ≥48hrs) "event-based" ("symptom-based" plus requiring antibiotics, corticosteroids, unscheduled healthcare use) estimated in separate models. Generalized estimating equations (GEE) models reported as rate ratios (RRs) per interquartile range (IQR) increment concentration 95% confidence intervals (95% CIs). NO2, PM2.5, Ox (NO2+O3) concentrations (but not O3) fell significantly In 673 participants both symptom-based event-based exacerbation rates likewise higher pre-pandemic period. During period, was positively associated (RR: 1.21 [1.08,1.36]). pandemic (1.46 [1.13,1.89]) (1.43 [1.00,2.05]) exacerbations. Fewer self-reported protective behaviors, viral infectious symptoms, also stepwise multivariable risk-factor analyses, female gender (1.23 [1.04,1.45] 1.41 [1.13,1.76]) co-morbid asthma (1.65 [1.34,2.03] 1.54 [1.19,2.00]) exacerbations, respectively, blood eosinophils (1.42 [1.10,1.84]) IQR (1.31 [1.06,1.61]). exposure consistently gender, asthma, eosinophilia found to be relevant
Язык: Английский
Процитировано
0
Atmospheric Pollution Research, Год журнала: 2025, Номер unknown, С. 102525 - 102525
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0
BMC Public Health, Год журнала: 2025, Номер 25(1)
Опубликована: Апрель 15, 2025
Air pollution is a significant public health concern, increasingly recognized for its association with adverse outcomes including neurodegenerative and neuroinflammatory conditions. The present study aimed to characterize plasma levels of key biomarkers related neurodegeneration neuroinflammation among middle-aged elderly adults living in areas designated as critically polluted. A total 202 adults, aged 41 60 years, residing CPA (CEPI > 70) over ten years were recruited the study. exposures air pollutant measured per established protocols by CPCB. markers (Aβ(1-42), Total τ, α-Synuclein, BDNF GFAP) estimated using commercially available ultra-sensitive ELISA kits. data analysis was performed through mean standard deviation, percentile distribution multivariate logistic regression SPSS 26.0. This confirmed elevated PM2.5 at location exceeding regulatory limits. Women exhibited relatively higher Amyloid Aβ(1-42), α-Synuclein GFAP levels, while men & levels. Further, older participants (aged 50 - years) all but compared younger peers 40 years). weak positive trend (p = 0.08) observed prolonged exposure. first community-based investigations India assess apparently healthy chronically exposed high ambient pollution. By integrating chronic exposure from Critically Polluted Area biomarker profiling, offers early insights into potential neurobiological alterations associated environmental pollutants, highlighting sex- age-specific vulnerabilities. These findings emphasize importance considering influences disease research need tailored interventions.
Язык: Английский
Процитировано
0
Atmosphere, Год журнала: 2023, Номер 14(12), С. 1759 - 1759
Опубликована: Ноя. 29, 2023
Urban air pollution is one of the major challenges that cities around world face. Particulate matter (PM), nitrogen dioxide (NO2), volatile organic compounds (VOCs), and other pollutants are many times over recommended airborne exposure, generating a strong impact on human health city well-being. Considering Bucharest as case study, this study aimed to investigate patterns particulate concentrations. Multiyear data from Romanian National Air Quality Monitoring Network were used spatial temporal variability. All presented typical bimodal trend during day, with specific double peaks corresponding morning rush hours nighttime. Spatial variability in NO2 concentrations was observed, almost concentration values center midday compared those for background industrial areas. A weekly pattern PM noticed, lower weekends comparison weekdays, more pronounced PM10 PM2.5. The fine particle fraction monthly seasonal variability, higher levels cold months warm months, mainly increased household heating. estimated proportion mortality attributable annual exposure an PM2.5 above 5 μg/m3 ranged between 7.55% 8.26%, maximum 2021. By contrast, 10 significantly lower, 4%. results useful supporting environmental planning measures decrease urban pollution.
Язык: Английский
Процитировано
3
Atmosphere, Год журнала: 2024, Номер 15(5), С. 593 - 593
Опубликована: Май 13, 2024
In addition to the detrimental health consequences, early stages of COVID-19 pandemic have yielded unforeseen benefits in terms reducing air pollution emissions. This study investigated changes Novi Sad, Serbia, during lockdown (March–June 2020) and their correlation with acute exacerbations chronic obstructive pulmonary disease (AECOPD) hospitalizations. Using quasi-Poisson generalized linear models (GLM) distributed lag non-linear (DLNM), we examined relationship between number AECOPD hospitalizations concentrations selected pollutants (PM10, PM2.5, SO2, NO2) from March June 2019, 2020, 2021. During lockdown, significant reductions most pollutant were observed. However, neither year nor its interaction concentration significantly predicted (p > 0.05). The 95% confidence intervals relative risks for occurrence at each increase by 10 μg/m3 overlapped across years, suggesting consistent effects on risk pre-pandemic lockdown. conclusion, reduced emissions did not lead a statistically change
Язык: Английский
Процитировано
0
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
0