Clinical Spectrum of Long COVID: Effects on Female Reproductive Health

Viruses, Год журнала: 2024, Номер 16(7), С. 1142 - 1142

Опубликована: Июль 16, 2024

The COVID-19 pandemic caused by SARS-CoV-2 has presented numerous health challenges, including long-term COVID, which affects female reproductive health. This review consolidates the current research on impact of menstrual cycle, ovarian function, fertility, and overall gynecological study emphasizes role angiotensin-converting enzyme receptors in viral entry subsequent tissue-specific pathological effects. It also explores potential influence long COVID hormonal balance immune responses, contributing to irregularities impaired function. findings indicate a higher prevalence among women, highlighting substantial implications for need sex-sensitive longitudinal studies. Enhanced surveillance targeted are essential develop effective interventions that prioritize women's well-being following infection. advocates sex-informed approach ongoing healthcare strategies, aiming provide up-to-date pertinent data providers general public, ultimately improving outcomes females affected COVID.

Язык: Английский

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The Significance of Endothelial Dysfunction in Long COVID-19 for the Possible Future Pandemic of Chronic Kidney Disease and Cardiovascular Disease

Biomolecules, Год журнала: 2024, Номер 14(8), С. 965 - 965

Опубликована: Авг. 8, 2024

Various symptoms have been reported to persist beyond the acute phase of severe respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, which is referred as long disease 19 (long COVID-19). Over 65 million individuals suffer from COVID-19. However, causes COVID-19 are largely unknown. Since observed throughout body, vascular endothelial dysfunction a strong candidate explaining induction The angiotensin-converting enzyme (ACE2), entry receptor for SARS-CoV-2, ubiquitously expressed in cells. We previously found that risk factors atherosclerotic cardiovascular (ASCVD) and history ASCVD raise COVID-19, suggesting contribution pre-existing Here, we show significant association with development biomarkers patients also crucial players ASCVD. consider influence on chronic kidney (CKD) Future assessments outcomes resulting therapeutic interventions improve function may imply significance

Язык: Английский

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Age-dependent phenotypes of cognitive impairment as sequelae of SARS-CoV-2 infection

Frontiers in Aging Neuroscience, Год журнала: 2025, Номер 16

Опубликована: Янв. 7, 2025

Cognitive changes associated with PASC may not be uniform across populations. We conducted individual-level pooled analyses and meta-analyses of cognitive assessments from eight prospective cohorts, comprising 2,105 patients 1,432 controls Argentina, Canada, Chile, Greece, India, Italy, Russia, the UK. The meta-analysis found no differences by country origin. profile severity impairment varied age, mild attentional observed in young middle-aged adults, but memory, language, executive function older adults. risk moderate to severe doubled Moderately or was significantly infection diagnoses (chi-square = 26.57, p ≤ 0.0001) anosmia 31.81, 0.0001). distinct age-related phenotypes recovering COVID-19. identified acute illness presence olfactory dysfunction as primary predictors dementia-like

Язык: Английский

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A Significance of Endothelial Dysfunction in Long COVID-19 for The Possible Future Pandemic of Chronic Kidney Disease and Cardiovascular Disease

Опубликована: Июнь 21, 2024

Various symptoms have been reported to persist beyond acute phase of severe respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, which is referred as long disease 19 (long COVID-19). Over 65 million individuals suffer from COVID-19. However, the causes COVID-19 largely unknown. Since are observed throughout body, vascular endothelial dysfunction may be a strong candidate induce The angioten-sin-converting enzyme (ACE2), entry receptor SARS-CoV-2, ubiquitously expressed in cells. We previously found that risk factors for athero-sclerotic cardiovascular (ASCVD) and history ASCVD can COVID-19, suggesting contribution pre-existing Here, we show significant association with development biomarkers patients also crucial players ASCVD. consider influence on chronic kidney (CKD) Furthermore, suggest therapeutic interventions by considering treatment tar-gets Such prevent pandemic CKD post era.

Язык: Английский

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Age-Dependent Phenotypes of Cognitive Impairment as Sequelae of Sars-Cov-2 Infection

Опубликована: Янв. 1, 2024

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Язык: Английский

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