Journal of Racial and Ethnic Health Disparities, Год журнала: 2024, Номер unknown
Опубликована: Авг. 22, 2024
Differences in acute COVID-19 associated morbidity based on race, ethnicity, and gender have been well described; however, less is known about differences subsequent longer term health-related quality of life well-being.
Язык: Английский
BMC Public Health, Год журнала: 2025, Номер 25(1)
Опубликована: Янв. 17, 2025
In Uganda, many people self-medicate and the practice raises important questions about access to healthcare, patient choices, increasing prevalence of antimicrobial resistance. This systematic review meta-analysis investigated factors associated with self-medication in Uganda. We searched Scopus, PubMed, Embase databases, WHO AFRO, UNIPH registries, Google Scholar search engine from inception November 2024 using algorithm "Self-Medication" AND "Uganda". Twenty-two eligible studies were included while adhering preferred reporting items for reviews (PRISMA). A total 9113 participants represented across different demographics regions Our analysis revealed a 55.63% (95%CI [40.40; 70.66] pooled Antibiotics are commonly self-medicated drugs ease medications, perceived cost effectiveness, long hospital waiting time, home storage (leftovers), perceptions minor illnesses key contributors behaviour. At least 1 2 Ugandans antibiotics constitute dominant compounding situation an era Awareness campaigns on dangers will be timely.
Язык: Английский
Процитировано
2
Journal of the American Medical Informatics Association, Год журнала: 2025, Номер unknown
Опубликована: Фев. 27, 2025
Direct electronic access to multiple health record (EHR) systems through patient portals offers a novel avenue for decentralized research. Given the critical value of characterization, we sought compare computable evaluation conditions from patient-portal EHR against traditional self-report. In nationwide Innovative Support Patients with SARS-CoV-2 Infections Registry (INSPIRE) study, which linked self-reported questionnaires multiplatform data, compared across different clinical domains definitions based on diagnosis codes, medications, vital signs, and laboratory testing. We assessed their concordance using Cohen's Kappa prognostic significance differentially captured features as predictors 1-year all-cause hospitalization risk. Among 1683 participants (mean age 41 ± 15 years, 67% female, 63% non-Hispanic Whites), prevalence varied substantially between self-report (-13.2% +11.6% definitions). Compared comprehensive phenotypes, under-captured all conditions, including hypertension (27.9% vs 16.2%), diabetes (10.1% 6.2%), heart disease (8.5% 4.3%). However, codes alone were insufficient. The risk was better defined by same (area under receiver operating curve [AUROC] 0.79) than (AUROC 0.68). EHR-derived phenotypes identified higher comorbidities self-report, additionally features. solely often undercaptured suggesting role broader elements. this patient-portal-derived data enabled extensive capture characteristics platforms, allowing phenotyping
Язык: Английский
Процитировано
1
Archives of Microbiology & Immunology, Год журнала: 2025, Номер 9(1)
Опубликована: Янв. 1, 2025
SARS-CoV-2 infection has led to a range of long-lasting symptoms, collectively referred as long COVID. Current research highlights the critical role angiotensin-converting enzyme 2 (ACE2) in regulating gut microbiota diversity, vascular function, and homeostasis within renin-angiotensin system (RAS). ACE2 is utilized by virus enter host cells, but its downregulation following contributes dysbiosis RAS disruption. These imbalances have been linked COVID including joint pain, chest chronic cough, fatigue, brain fog, anxiety, depression, myalgia, peripheral neuropathy, memory difficulties, impaired attention. This review investigates dysregulation caused long-term effects it on various organ systems, musculoskeletal, neurological, renal, respiratory, cardiovascular systems. We explored bidirectional interactions between microbiota, immune these focusing how inflammation dysfunction observed symptoms. Understanding key for identifying effective therapeutic strategies interventional targets aimed at mitigating impact health improving patient outcomes.
Язык: Английский
Процитировано
1
Health Research Policy and Systems, Год журнала: 2025, Номер 23(1)
Опубликована: Янв. 20, 2025
Obesity is a multi-faceted problem that requires complex health system responses. While no single program or service sufficient to meet every individual's needs, some criteria increase the likelihood of program/service quality delivery produce effective outcomes exist. However, although research on commissioning available internationally and growing within Australian context, evidence exists multi-criteria decision-making framework address complexity required for overweight obesity early intervention weight management programs services. This study aimed develop set support in this context. A mixed-methods co-design approach was used framework. literature review informed three-stage consensus-gathering approach. Participants included Western stakeholders from system, services consumers, who reviewed, ranked validated responses through ongoing discussions. deliberative forum held between two online, modified Delphi surveys reach consensus among stakeholders. Through co-design, total 63 were identified: 24 completed round 1 survey assessing 22 proposed criteria, 40 attended 30 2 survey. 4 themes arose process: (1) reduce duplication, (2) demote (3) re-organize (4) simplify language, 10 established: safety, collaboration consultation, appropriateness, effectiveness, efficiency, equity, evidence-based, model, sustainability workforce capacity competence. The underpinned by indicators highlighting relevant sub-themes. developed its application process will enable selection likely have an impact individuals' use satisfaction with services, obesity-related inter-agency collaborations maximize economic resources.
Язык: Английский
Процитировано
0
Calcified Tissue International, Год журнала: 2024, Номер 114(3), С. 276 - 285
Опубликована: Янв. 23, 2024
Язык: Английский
Процитировано
3
Women s Health Reports, Год журнала: 2025, Номер 6(1), С. 21 - 28
Опубликована: Янв. 1, 2025
This mixed-method study sought to elucidate the impact of COVID-19 on professional environments and career trajectories midcareer research faculty in U.S. medical schools. Participants were 40 school enrolled Brandeis University C-Change Mentoring Leadership Institute, a group peer mentoring development course being tested National Institutes Health-funded randomized controlled trial. We observed gender disparity both quantitative qualitative data, with women describing more negatively impacting their trajectory. negative was independent having children home. largely reported no change commitment conducting or interest applying for funding. A total 54% effect pandemic relationships colleagues (n = 21) 33% 13). trend emerged when examining data by degree, however, PhD about twice as likely physicians report relationship (47% n 9 vs. 20% 4, respectively). The ordinal test 5-point scale approached statistical significance but did not meet standard 0.05 cut-off (p value 0.06; Z-value -1.86). While initially some positive outcomes SARS-CoV-2 own experiences April 2020, 1 year later reflected impacts trajectory, especially women, colleagues, higher intensity signal scientists.
Язык: Английский
Процитировано
0
Journal of Racial and Ethnic Health Disparities, Год журнала: 2024, Номер unknown
Опубликована: Авг. 22, 2024
Differences in acute COVID-19 associated morbidity based on race, ethnicity, and gender have been well described; however, less is known about differences subsequent longer term health-related quality of life well-being.
Язык: Английский
Процитировано
0