Regional features of sensitization to various allergens in children with allergic diseases, taking into account the formed exposome. DOI

Ivan S. Sadovsky,

А. Г. Борисов,

Snezhana V. Bychkovskaya

и другие.

Cytokines and inflammation, Год журнала: 2024, Номер 20(4), С. 35 - 48

Опубликована: Авг. 19, 2024

BACKGROUND: According to data from the World Health Organisation, up 40% of world’s population and 35% Russian suffer allergies. Assessing impact exposome in Federation is a crucial issue national public health care, which will provide personalised approach treatment prevention allergic diseases local population. AIM: To evaluate sensitisation profile children with different regions Russia. MATERIALS AND METHODS: The study included sick aged 2 12 years manifestations Federation. concentration total IgE allergen-specific immunoglobulins blood was determined retrospectively on basis analyses results obtained clinical diagnostic laboratories performing immunoblotting tests using Allergy-Q® test system (South Korea). RESULTS: Sensitisation allergens mediated by detected more frequently than half cases (436 people — 58.39%). In group household first place occupied cat, then dog already house dust. Among respiratory allergens, birch and/or other trees, weeds mugwort are leaders. Food mainly milk, egg, fish seafood. CONCLUSIONS: peculiarities revealed easily explained formed exposomes (due climatic conditions, regional vegetation nutrition). can be used develop measures prevention, diagnosis diseases.

Язык: Английский

Global research trends on the human exposome: a bibliometric analysis (2005–2024) DOI Creative Commons
Pascal Petit, Nicolas Vuillerme

Environmental Science and Pollution Research, Год журнала: 2025, Номер unknown

Опубликована: Март 8, 2025

Abstract Exposome represents one of the most pressing issues in environmental science research field. However, a comprehensive summary worldwide human exposome is lacking. We aimed to explore bibliometric characteristics scientific publications on exposome. A analysis from 2005 December 2024 was conducted using Web Science accordance with PRISMA guidelines. Trends/hotspots were investigated keyword frequency, co-occurrence, and thematic map. Sex disparities terms citations examined. From 2024, 931 published 363 journals written by 4529 authors 72 countries. The number tripled during last 5 years. Publications females (51% as first 34% authors) cited fewer times (13,674) than males (22,361). Human studies mainly focused air pollution, metabolomics, chemicals (e.g., per- polyfluoroalkyl substances (PFAS), endocrine-disrupting chemicals, pesticides), early-life exposure, biomarkers, microbiome, omics, cancer, reproductive disorders. Social built environment factors, occupational multi-exposure, digital exposure screen use), climate change, late-life received less attention. Our results uncovered high-impact countries, institutions, journals, references, authors, key trends/hotspots. use technologies sensors, wearables) data artificial intelligence) has blossomed overcome challenges could provide valuable knowledge toward precision prevention. risk scores represent promising avenue.

Язык: Английский

Процитировано

0

Regional features of sensitization to various allergens in children with allergic diseases, taking into account the formed exposome. DOI

Ivan S. Sadovsky,

А. Г. Борисов,

Snezhana V. Bychkovskaya

и другие.

Cytokines and inflammation, Год журнала: 2024, Номер 20(4), С. 35 - 48

Опубликована: Авг. 19, 2024

BACKGROUND: According to data from the World Health Organisation, up 40% of world’s population and 35% Russian suffer allergies. Assessing impact exposome in Federation is a crucial issue national public health care, which will provide personalised approach treatment prevention allergic diseases local population. AIM: To evaluate sensitisation profile children with different regions Russia. MATERIALS AND METHODS: The study included sick aged 2 12 years manifestations Federation. concentration total IgE allergen-specific immunoglobulins blood was determined retrospectively on basis analyses results obtained clinical diagnostic laboratories performing immunoblotting tests using Allergy-Q® test system (South Korea). RESULTS: Sensitisation allergens mediated by detected more frequently than half cases (436 people — 58.39%). In group household first place occupied cat, then dog already house dust. Among respiratory allergens, birch and/or other trees, weeds mugwort are leaders. Food mainly milk, egg, fish seafood. CONCLUSIONS: peculiarities revealed easily explained formed exposomes (due climatic conditions, regional vegetation nutrition). can be used develop measures prevention, diagnosis diseases.

Язык: Английский

Процитировано

0