Exposome within the Context of the Public Health Perspectives
Journal of Comprehensive Health,
Год журнала:
2025,
Номер
0, С. 1 - 10
Опубликована: Фев. 15, 2025
Genetics
account
for
a
small
proportion
of
diseases,
and
the
remaining
causes
appear
to
be
environmental.
The
classic
epidemiological
approach
is
study
each
cause-effect
relationship
separately.
This
does
not
consider
linked
complex
interactions
between
different
exposures
throughout
life
course.
exposome
new
concept
in
health
research.
It
focuses
on
integrating
environmental
from
conception
death
with
human
genome
their
effects
health.
complements
but
mirror
genome.
dynamic
includes
many
domains,
domains
complex.
These
include
internal
biological
processes,
general
external
environment,
individual’s
local
immediate
environment.
Environmental
need
studied
understand
mechanisms
diseases
formulate
prevention
strategies.
Many
designs,
assessment
tools,
methods
are
currently
used
unravel
its
at
levels
population
span.
While
application
may
individual
level,
will
applied
population.
Therefore,
likely
benefit
public
rather
than
clinical
practice.
narrative
review
aims
provide
readers
current
status
research,
relevance
medicine,
as
well
future
challenges.
most
important
challenges
methodological
statistical
issues,
identification
novel
biomarkers,
big
data
management
using
artificial
intelligence,
ethical
economic
considerations,
integration
one
syndemic
approaches,
lastly,
sharing
international
cooperation.
Язык: Английский
Global research trends on the human exposome: a bibliometric analysis (2005–2024)
Environmental Science and Pollution Research,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 8, 2025
Abstract
Exposome
represents
one
of
the
most
pressing
issues
in
environmental
science
research
field.
However,
a
comprehensive
summary
worldwide
human
exposome
is
lacking.
We
aimed
to
explore
bibliometric
characteristics
scientific
publications
on
exposome.
A
analysis
from
2005
December
2024
was
conducted
using
Web
Science
accordance
with
PRISMA
guidelines.
Trends/hotspots
were
investigated
keyword
frequency,
co-occurrence,
and
thematic
map.
Sex
disparities
terms
citations
examined.
From
2024,
931
published
363
journals
written
by
4529
authors
72
countries.
The
number
tripled
during
last
5
years.
Publications
females
(51%
as
first
34%
authors)
cited
fewer
times
(13,674)
than
males
(22,361).
Human
studies
mainly
focused
air
pollution,
metabolomics,
chemicals
(e.g.,
per-
polyfluoroalkyl
substances
(PFAS),
endocrine-disrupting
chemicals,
pesticides),
early-life
exposure,
biomarkers,
microbiome,
omics,
cancer,
reproductive
disorders.
Social
built
environment
factors,
occupational
multi-exposure,
digital
exposure
screen
use),
climate
change,
late-life
received
less
attention.
Our
results
uncovered
high-impact
countries,
institutions,
journals,
references,
authors,
key
trends/hotspots.
use
technologies
sensors,
wearables)
data
artificial
intelligence)
has
blossomed
overcome
challenges
could
provide
valuable
knowledge
toward
precision
prevention.
risk
scores
represent
promising
avenue.
Язык: Английский