Bovine serum albumin nanoparticles encapsulating Dasatinib and Celecoxib for oral cancer: Preparation, characterization, and in-vitro evaluation

Naunyn-Schmiedeberg s Archives of Pharmacology, Год журнала: 2025, Номер unknown

Опубликована: Фев. 12, 2025

Язык: Английский

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Editorial: Unravelling the role of the oral microbiome in cancer

Frontiers in Oral Health, Год журнала: 2025, Номер 6

Опубликована: Апрель 29, 2025

Язык: Английский

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Porphyromonas gingivalis and Human Cytomegalovirus Co-Infection: A Potential Link Between Periodontal Disease and Oral Cancer Development

Cancers, Год журнала: 2025, Номер 17(9), С. 1525 - 1525

Опубликована: Апрель 30, 2025

Periodontal disease (PD) is an inflammatory condition that can contribute to the development of oral cancer. Chronic inflammation from PD lead release mediators and growth factors promote tumorigenesis. Porphyromonas gingivalis (P. gingivalis) one several pathogens implicated in its potential link However, other viral infections, such as human cytomegalovirus (HCMV), also chronic inflammation, creating a favorable environment for cancer development. Objectives: The present literature review tries investigate possible influence P. HCMV co-infection fostering periodontitis. Methods: A comprehensive search was conducted PubMed Google Scholar, focusing on relevance significance articles examine role periodontal Results: evidence suggests may act synergistically modulate host immunity, disrupt epithelial integrity, interfere with key cellular pathways. These interactions enhance tissue destruction foster microenvironment conducive malignant transformation. most these findings stem vitro models small-scale clinical studies, limiting generalizability current conclusions. Conclusions: Although proposed interaction between provides compelling framework understanding how microbial co-infections cancer, remains preliminary largely associative. To support mechanistic hypotheses, future studies should give top priority vivo models, bigger patient cohorts, longitudinal studies.

Язык: Английский

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Advances in Photothermal Therapy for Oral Cancer

International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(9), С. 4344 - 4344

Опубликована: Май 2, 2025

Oral cancer represents a critical global health issue, where traditional treatment modalities are often characterized by considerable adverse effects and suboptimal effectiveness. Photothermal therapy (PTT) offers an innovative method for tumor treatment, leveraging photothermal agents to convert light into hyperthermia, ultimately leading ablation. PTT unique advantages in treating oral due its superficial anatomical location consequent accessibility laser irradiation. PTT’s advantage is further enhanced capacity facilitate drug release promote tissue regeneration. Consequently, the application of has garnered widespread interest undergone rapid development. This review outlines advances cancer, emphasizing strategies improve efficacy combination approaches. The key challenges, including temperature control long-term biosafety, discussed alongside future directions. also encompasses role managing potentially malignant disorders postoperative defects, conditions intimately linked with cancer. We aim provide guidance emerging research development precise efficient strategies.

Язык: Английский

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Capacity building of community health officers for optimizing the screening and early diagnosis of oral cancer in Jodhpur, Rajasthan, India.

PubMed, Год журнала: 2025, Номер 15(1), С. 16027 - 16027

Опубликована: Май 8, 2025

Язык: Английский

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