PEMOCS: effects of a concept-guided, PErsonalized, MOtor-Cognitive exergame training on cognitive functions and gait in chronic Stroke—a randomized, controlled trial
Frontiers in Aging Neuroscience,
Год журнала:
2025,
Номер
17
Опубликована: Март 13, 2025
Purpose
Motor-cognitive
exergames
may
be
beneficial
for
addressing
both
motor
and
cognitive
residual
impairments
in
chronic
stroke,
however,
effective
training
schedules
are
yet
to
determined.
Therefore,
this
study
investigates
the
effects
of
a
concept-guided,
personalized,
motor-cognitive
exergame
on
functions
gait
stroke
survivors.
Methods
In
single-blind,
randomized,
controlled
trial,
survivors
(at
least
six-months
post-stroke
able
perform
step-based
exergaming)
were
allocated
either
intervention
(usual
care
+
training)
or
control
group
only).
Global
functioning
was
primarily
targeted,
while
health-related
quality
life
(HRQoL),
functions,
mobility,
evaluated
secondarily.
Analyses
performed
with
linear-mixed
effect
models.
Results
Effects
global
non-significant,
no
differences
between
responders
(participants
exhibiting
clinically
relevant
change)
non-responders
change).
Among
secondary
outcomes,
mobility
domain
HRQoL
questionnaire,
intrinsic
visual
alertness,
flexibility,
working
memory,
outdoor
walking
speed
as
well
swing
width
(unaffected
side)
showed
significant
interaction
favour
group.
Discussion
Additional
exergaming
helped
maintaining
encouraging
outcomes.
Responders
did
not
differ
adherence,
baseline
values
age.
Enhancing
frequency
intensity
sessions
could
unlock
more
substantial
benefits.
Adopting
blended
therapy
approach
key
maximizing
positive
effects.
Clinical
trial
registration
clinicaltrials.gov
,
identifier
NCT05524727.
Язык: Английский
PEMOCS: Evaluating the effects of a concept-guided, PErsonalised, MOtor-Cognitive exergame training on cognitive functions and gait in chronic Stroke—study protocol for a randomised controlled trial
Trials,
Год журнала:
2024,
Номер
25(1)
Опубликована: Июль 4, 2024
Abstract
Background
Many
stroke
survivors
remain
with
residual
cognitive
and
motor
impairments
despite
receiving
timely
acute
sub-acute
rehabilitation.
This
indicates
that
rehabilitation
following
should
be
continuous
to
meet
the
needs
of
individual
patients.
Both
functions
are
essential
for
mastering
daily
life
and,
therefore,
aimed
at
Exergames,
motor-cognitive
exercises
performed
using
video
games,
an
auspicious
method
train
both
same
time
may
foster
long-term
motivation
training.
study
aims
assess
effect
concept-guided,
personalised,
exergame
training
on
in
chronic
survivors.
Methods
is
a
single-blinded,
randomised
controlled
trial.
Assessments
baseline,
after
12-week
intervention,
24-weeks
follow-up.
Chronic
patients
(≥
18
years
old,
≥
6
months
post-stroke)
able
stand
3
min,
independently
walk
10
m,
follow
two-stage
command,
without
other
neurological
diseases
apart
from
deficits
or
dementia
included.
Participants
intervention
group
perform
twice
per
week
30
(beginning)
up
40
(end)
minutes
additionally
their
usual
care
programme.
control
receive
additional
intervention(s).
Global
functioning
(total
Montreal
Cognitive
Assessment
(MoCA)
score)
primary
outcome.
Secondary
outcomes
include
health-related
quality
life,
specific
functions,
single-
dual-task
mobility,
spatiotemporal
gait
parameters.
The
target
sample
size
this
trial
38
participants.
Linear
mixed
models
post-outcome
scores
as
dependent
variables
fixed
effects
will
analysis.
Discussion
Superior
improvements
global
abovementioned
secondary
compared
hypothesised.
results
guide
future
design
interventions
stroke.
Trial
registration
ClinicalTrials.gov
(NCT05524727).
Registered
September
1,
2022.
Язык: Английский