A Modified Bi-Directional Convolutional U-Net (BCDU-Net) Neural Network Approach for Lung CT Image Segmentation

Journal of biomimetics, biomaterials and biomedical engineering, Год журнала: 2025, Номер 67, С. 9 - 20

Опубликована: Янв. 15, 2025

In this paper, a modified Bi-directional Convolutional Long Short-Term Memory U-Net (BCDU-Net) neural network is presented, which aims at enhancing medical image segmentation for lung cancer diagnosis. By integrating BConvLSTM in the decoding path and densely connected convolutional layers encoding path, proposed model achieves greater stability precision segmenting CT images. The addition of Batch Normalization (BN) after up-convolutional accelerates convergence speed by six times. A notable feature BCDU-Net its adaptability to different imaging modalities, enabling it generalize across diverse data sources reducing overfitting, limitation seen many existing models. This allows model’s ability be integrated into various clinical environments, ensuring consistent reliable results equipment. Another key contribution enhanced interpretability model, critical improvement when compared with traditional accurately segments complex anatomical structures, such as left right lungs, precisely identifies tumors near central bronchi or trachea airways, crucial treatment planning. was tested on Cancer Imaging Archive (TCIA) dataset from 2017 Lung Segmentation Challenge, achieving Dice Similarity Coefficients (DSC) 97.97 97.73 lung. Overall, demonstrates superior accuracy holds promise broader applications beyond

Язык: Английский

Analysis of the Safety of Bronchoscopy in Patients Aged 80 Years and Older: A Retrospective Study

Research Square (Research Square), Год журнала: 2025, Номер unknown

Опубликована: Апрель 3, 2025

Background The safety of bronchoscopy in elderly patients, particularly those aged 80 years and older, remains a concern due to age-related comorbidities. This study evaluates clinical characteristics, preoperative cardiovascular pulmonary indicators, bronchoscopy-related complications across different age groups. Methods A retrospective 349 patients undergoing was conducted. Patients were categorized into three groups: Young (< 65 years, n = 120), Elderly (65–79 Oldest (≥ 109). Demographics, procedural analyzed. Results oldest group exhibited significantly higher rates conditions, including arrhythmia (76.15%), hypertension (36.70%), elevated D-dimer levels (54.13%) (all p < 0.01). Pulmonary function more impaired, with increased emphysema (27.52%) respiratory failure (25.69%) However, intraoperative such as mild bleeding (93.58%) hypoxia (6.42%) not Post-procedural recovery favorable 96.33% patients. Conclusions Bronchoscopy is generally safe ≥ when appropriate precautions are taken. Careful assessment critical minimizing risks. Trial registration Clinical trial number applicable.

Язык: Английский