Food Bioscience, Год журнала: 2024, Номер unknown, С. 105718 - 105718
Опубликована: Дек. 1, 2024
Язык: Английский
International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(2), С. 548 - 548
Опубликована: Янв. 10, 2025
The sustainable utilization of biomass-derived bioactives addresses the growing demand for natural health products and supports development goals by reducing reliance on synthetic chemicals in healthcare. Cannabis sativa biomass, particular, has emerged as a valuable resource within this context. This study focuses hydroethanolic extract C. leaves (CSE), which exhibited significant levels phenolic compounds contributing to robust antioxidant activity. Evaluation using potassium ferricyanide, ABTS, DPPH methods revealed potent radical scavenging activity comparable Trolox standard. UPLC-MS/MS profiling identified cannabinoids predominant secondary metabolites CSE, with flavonoids also present substantial quantities. investigated anti-inflammatory potential CSE RAW 264.7 macrophages IL-1β-stimulated C-20/A4 immortalized human chondrocytes, demonstrating protective effects without cytotoxic or mutagenic effects. Mechanistically, reduced inflammation inhibiting MAPK NF-κB signaling pathways. In silico approaches showed ability CSE's main bind influence activity, confirming vitro evidence. Incorporating leaf into hyaluronic acid-based formulation biotechnological promise treating joint inflammation. Future research should aim elucidate molecular mechanisms underlying these explore CSE-derived mitigating osteoarthritis progression. approach highlights significance utilizing annually increasing biomass waste bioactivity environmental impact reduction.
Язык: Английский
Процитировано
0
Microorganisms, Год журнала: 2025, Номер 13(2), С. 455 - 455
Опубликована: Фев. 19, 2025
Biomass residues represent a major issue for industries. On the other hand, enclosed classes of bioactive compounds that could be extracted and used across various fields. This study aimed to elucidate role endogenous microbial community in lignocellulosic degradation hemp biorefineries or industrial processes, simultaneously characterizing composition three extracts recovered at different stages maceration. The process was examined from perspectives: plant tissue dynamics were monitored using histological, cultural-dependent, independent analysis. Extracts characterized through FTIR, NMR, SDS-PAGE analyses, also evaluating their potential as biostimulants growth. Results revealed prokaryotic remained stable during maceration period, while fluctuations fungal genera observed. taxonomical may account increased accumulation amide-containing compounds, sugars, metabolites detected long-term bioconversion. Finally, able support growth yeast Cryptococcus phenolicus bacterium Peribacillus simplex sole source nitrogen, paving way use biostimulants.
Язык: Английский
Процитировано
0
Applied Sciences, Год журнала: 2024, Номер 14(22), С. 10460 - 10460
Опубликована: Ноя. 13, 2024
Opuntia macrorhiza, commonly referred to as red prickly pear, is a type of cactus fruit. The macrorhiza (OM) fruit rich in polyphenols and contains high amount ascorbic acid betalains. peels have demonstrated many biological abilities, including antioxidant, antifungal, antibacterial activities. Ultrasound probe-assisted extraction (UPAE) highly promising method for efficiently extracting valuable molecules from natural sources. objective this study optimize the parameters UPAE, appropriate solvent, liquid-to-solid ratio, duration, pulsation level. aim maximize yield bioactive compounds (polyphenols, betalains, acid) OM fruits (pulps peels) assess their antioxidant activities using Taguchi design. optimal conditions through partial least squares pulp were determined be aqueous 12 min with ratio 60 mL/g 48 pulses/min, while they 20 pulses/min. optimum UPAE compared values obtained under stirring (STE). Overall, exhibited higher yields than STE. total polyphenol content ranged 10.27 13.07 mg gallic equivalents/g dry weight, betalain 974 1099 μg/g weight. these potential new components food medicinal uses due good health effects lack toxicity.
Язык: Английский
Процитировано
3
Waste, Год журнала: 2024, Номер 2(3), С. 382 - 396
Опубликована: Сен. 20, 2024
Pyrus communis (P. communis) is the most cultivated and consumed species of pear within European continent. This fruit has been a staple in Greece since ancient times, hence name “Gift Gods”. Given extensive utilization this industrial sector focus on exploitation by-products to create new food beverage products, present research aimed enhance antioxidant activity P. peel through implementation multifactor extraction system. Increased total polyphenols ascorbic acid concentration, enhanced radical scavenging Fe3⁺ Fe2⁺ reduction, all assist boosting health benefits extracts. The results indicated that best conditions for compound yields were 75% v/v hydroethanolic an temperature 80 °C, 30 min time. Under optimal conditions, polyphenol content was up 4.98 mg gallic equivalents (GAE)/g dried weight (dw). by 2,2-diphenyl-1-picrylhydrazyl (DPPH•) method expressed as 18.36 μmol (AAE)/g dw, while ferric-reducing power (FRAP) method, it 35.09 AAE/g dw. Finally, amount measured at 20.16 mg/100 g In regard, study conducted assess level these bioactive compounds extract peel, leading with several applications different industries.
Язык: Английский
Процитировано
1
AgriEngineering, Год журнала: 2024, Номер 7(1), С. 1 - 1
Опубликована: Дек. 24, 2024
Cannabis sativa, often called hemp, is a medicinal plant belonging to the Cannabaceae family and widely recognized for its therapeutic applications. After industrial supercritical CO2 extraction method, hemp residue biomass was recovered, significant quantity of bioactive compounds identified. Therefore, it paramount importance study whether they can be further exploited using green techniques. In present work, leaf residues were treated two techniques: one conventional stirring (STE) pressurized liquid (PLE). The latter technique promising swift method efficient valuable molecules from natural sources. techniques optimized through Response Surface Methodology, parameters appropriate solvent, temperature, duration. aim maximize yield (polyphenols, flavonoids, ascorbic acid) evaluate their antioxidant activity most technique. results showed that after three 5 min PLE cycles, recovered individual polyphenols comparable (p > 0.05) 45 STE (19.34 20.84 mg/g, respectively), as well in capacity assays other compounds. These findings emphasize efficacy rapid approach an effective enhance value while maximizing concentration high-added molecules.
Язык: Английский
Процитировано
0
Food Bioscience, Год журнала: 2024, Номер unknown, С. 105718 - 105718
Опубликована: Дек. 1, 2024
Язык: Английский
Процитировано
0