Pathogens, Год журнала: 2023, Номер 12(9), С. 1121 - 1121
Опубликована: Сен. 1, 2023
Consumer awareness of animal welfare and environmental health has led to a plateau level global consumption putting serious pressure on the livestock industry [...].
Язык: Английский
Applied Food Research, Год журнала: 2025, Номер unknown, С. 100738 - 100738
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
3
Frontiers in Veterinary Science, Год журнала: 2023, Номер 10
Опубликована: Апрель 25, 2023
Avian species have long struggled with the problem of coccidiosis, a disease that affects various parts intestine, including anterior gut, midgut, and hindgut. Among different types cecal coccidiosis is particularly dangerous to avian species. Chickens turkeys are commercial flocks; thus, their parasites remained critical due economic importance. High rates mortality morbidity observed in both chickens coccidiosis. Coccidiostats coccidiocidal chemicals traditionally been added feed water control However, after EU banned use because issues resistance public health, alternative methods being explored. Vaccines also used, but efficacy cost-effectiveness remain as challenges. Researchers attempting find alternatives, among botanicals promising choice. Botanicals contain multiple active compounds such phenolics, saponins, terpenes, sulfur compounds, etc., which can kill sporozoites oocysts stop replication Eimeria . These primarily used anticoccidials antioxidant immunomodulatory activities. Because medicinal properties botanicals, some products developed. further research needed confirm pharmacological effects, mechanisms action, concentrated preparation. In this review, an attempt has made summarize plants potential act explain mode action found within them.
Язык: Английский
Процитировано
31
Frontiers in Veterinary Science, Год журнала: 2025, Номер 12
Опубликована: Фев. 11, 2025
Haemonchus contortus (H. contortus) infection has a significant impact on the health of pregnant ewes and adversely affects fetal development, highlighting critical need for non-toxic feed additive as an alternative sustainable control strategy. Tannin is kind polyphenol compound, which certain antiparasitic. The objective this study was to evaluate dietary tannin supplementation fecal egg count (FEC), packed cell volume (PCV), complete blood (CBC), hormone levels, inflammatory markers, placental inflammation, growth development in infected with H. contortus. Hulunbuir were randomly divided into three groups: group (CON), gastrointestinal nematode (GIN), group, by feeding therapy (TAN). After artificial insemination completed, confirmed pregnancy infection; stools collected FEC, samples PCV CBC, hormonal, inflammation levels. mRNA levels hypothalamic-pituitary-ovarian axis-related receptors tissue genes detected quantitative reverse transcription polymerase chain reaction (RT-qPCR). Finally, weights measured, ovarian taken transcriptomic analysis. results showed that tannins increased gonadotropin-releasing (GnRH), follicle-stimulating (FSH), luteinizing (LH), estrogen (E2), progesterone (P4), human chorionic gonadotropin (hCG), red (RBC) counts, gonadotropic axis (p < 0.05). In addition, reduced leukocyte markers sequencing further may alleviate delay induced summary, have anthelmintic effects, restore reproductive ewes, reduce retardation caused infection. Therefore, suitable potential antibiotics additive.
Язык: Английский
Процитировано
0
Animals, Год журнала: 2025, Номер 15(4), С. 535 - 535
Опубликована: Фев. 13, 2025
Recent studies have highlighted the potential of plant-based and agro-industrial by-products as valuable sources bioactive compounds for animal feed formulation. This study aims to evaluate impact dietary supplementation with Olea europaea L. leaf extract on fatty acid composition pig muscle. Thirty commercial hybrid pigs (Large White × (Landrace Duroc)), an initial body weight 169 ± 7.90 kg average age 10 1 months, were randomly assigned two experimental groups (n = 15 per group): one fed a standard diet containing Sulla (C) other receiving same enriched olive (OL). Over 90 days, OL group was supplemented 300 mg/head/day extract, primarily oleuropein diglucoside, luteolin-7-glucoside, verbascoside. The phenolic content, antioxidant activity, compounds, profiles both meats diets analyzed. Results showed that did not significantly affect chemical meat or performance, but it influence lipid profile. Specifically, led significant reduction in saturated acids (SFAs) increase oleic acid, thus enhancing proportion monounsaturated (MUFAs). Moreover, n-6/n-3 PUFA ratio reduced, suggesting improvements nutritional functional quality meat, by improving its
Язык: Английский
Процитировано
0
Veterinary and Animal Science, Год журнала: 2025, Номер 28, С. 100439 - 100439
Опубликована: Март 4, 2025
Selective foraging has been reported in many wild and domesticated ruminants, yet modern livestock production systems rarely allow animals to express this natural behaviour. However, it is assumed that giving the opportunity for forage selection positively influences their health welfare. This study investigated of individual dairy cows on pasture. Over one grazing season, a herd 23 was observed an experimental pasture Switzerland, which consisted different plant mixtures. The had unrestricted access all mixtures behaviour documented by scan sampling. four were rich grasses (G), legumes (L), tanniferous plants (T), herbs containing essential oils (E). results revealed partial preference L mixture at level across rotations (P ≤ 0.001). All frequented, indicating utilized array available plants. Individual preferences varied not followed herd's average pattern. shifted throughout but pattern variability differed between animals. findings demonstrate actively select from vary individuals over time. Importantly, do accurately represent cows. should be considered when aiming meet needs members.
Язык: Английский
Процитировано
0
Frontiers in Veterinary Science, Год журнала: 2025, Номер 12
Опубликована: Март 12, 2025
Bioactive plants provide therapeutic and prophylactic effects to ruminants. We determined the effect of grazing on natural meadow grassland enriched with experimentally sown chicory ( Cichorium intybus ) parasitological status, pasture larval infectivity, antioxidant parameters, histology abomasal tissue in lambs infected parasitic gastrointestinal nematode (GIN) Haemonchus contortus. also qualitatively identified main polyphenols phenolic metabolites feces lambs. Sixteen were orally approximately 5,000 infective larvae (L3) H. contortus . The divided into two groups: a plot consisting exclusively which serves as control group where 25% was reclaimed chicory. experimental period 144 days. number eggs per gram (EPG) quantified D21, D34, D48, D62, D76, D89, D103, D118, D131, D144 post-infection. Pasture contamination L3 examined. EPG both groups highest at D34. Egg shedding significantly lower from D48 onwards, reduction >95% D103 onwards. D41 but then groups. total capacity, activity glutathione peroxidase concentration malondialdehyde serum changed during experiment p < 0.003, 0.001, 0.016, respectively). At least 54 species plots; plant bioactive compounds mainly acids, flavonoids, glucosides. Phenolic (e.g., coumaric acid, salvigenin, esters gallic acid) In some lambs, morphological observation small histopathological changes tissues typical hemonchosis. Both slowed dynamics GIN infection by mobilizing defensive system gradually increasing resistance probably due beneficial substances.
Язык: Английский
Процитировано
0
Antibiotics, Год журнала: 2025, Номер 14(4), С. 336 - 336
Опубликована: Март 24, 2025
Background/Objectives: Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii. The parasite infection in humans continues to rise due an increasing seroprevalence rate domestic and wild warm-blooded animals that serve as major reservoir of the parasite. There are fewer drugs available for treatment toxoplasmosis. However, these limited efficacy against tachyzoites bradyzoites. Also, there clinical side effects geographical barriers their use, especially immunocompromised patients, children, pregnant women. Tannins, class natural products, known have antimicrobial properties. little about Corilagin (CG) Punicalagin (PU), which classified tannins, on T. gondii growth possible mechanism action vitro. We hypothesize CG PU could inhibit vitro cause mitochondria membrane disruption via oxidative stress. Methods: Here, we investigated anti-T. activity two named tannins using fluorescent-based reporter assay. Results: 50% effective concentrations (EC50s) values inhibited parasites were determined be 3.09 19.33 µM, respectively. Pyrimethamine (PY) was used standard control gave EC50 value 0.25 µM. Interestingly, observed high reactive oxygen species (ROS) mitochondrial superoxide (MitoSOX) production tachyzoites. This resulted strong potential (MMP) Conclusions: Therefore, mechanism(s) associated with redox biology. Thus, ROS MitoSOX produced result compounds created stress, leading dysfunction.
Язык: Английский
Процитировано
0
The Pakistan Journal of Agricultural Sciences, Год журнала: 2023, Номер 60(04), С. 473 - 485
Опубликована: Дек. 1, 2023
Coccidiosis is one of the major parasitic diseases infecting almost all ruminants, including cows, buffalo, sheep, and goats. caused by genus Eimeria, which are host-specific obligate intestinal parasites. These found over world cause infections leading to mortalities morbidities. usually treated ionophores synthetic chemicals various classes chemical drugs. drugs have been effective against coccidiosis but emerging issues anthelmintic resistance, public health concerns, consumer demand for organic products minimizing use these Vaccination also being used, vaccine failure high cost limit their use. Among alternatives, herbal medicines promising replacements because complex formulations, multiple modes action, easy availability, cost-effectiveness. Various plants, parts, formulations like preparations, active compounds in them searched control ruminant coccidiosis. Multiple groups botanical i.e., Flavonoids, alkaloids, tannins, terpenes, sulfur compounds, etc. proven be coccidiosis-causing agents. They can stages Eimeria directly indirectly antioxidant immunomodulatory actions. Further research needed determine most suitable preparations pharmacological interactions sustainable ruminants. This review highlights significance coccidiosis, used mechanisms reasons benefits compounds.
Язык: Английский
Процитировано
7
Agriculture, Год журнала: 2024, Номер 14(5), С. 648 - 648
Опубликована: Апрель 23, 2024
Willow (Salix spp.) trees, found worldwide, contain secondary metabolites that are valuable as dietary supplements for animal feed and antiparasitic compounds. We quantified (phenolics, flavonoids, salicylic acid) in ethanolic extracts from leaves branches of three Salix acmophylla Boiss. genotypes investigated their potential to inhibit Eimeria sp. sporulation, a major concern ruminants. The total phenolic content willow was similar two different genotypes. flavonoid the significantly higher than same genotype; however, acid branches. Importantly, all exhibited significant inhibition where over 70% obtained at concentrations low 750 mgL−1. sporulation by branch or leaf exceeded 80% 90% above 1250 study highlights using bioactive compounds biological control coccidiosis conclude parts S. can provide act coccidiostat treat goats.
Язык: Английский
Процитировано
2
Agricultura Scientia, Год журнала: 2024, Номер unknown
Опубликована: Июнь 2, 2024
The potential of fodder tree legumes (FTL) as a promising and nutritional strategy to minimize the problem insufficient supply forages, especially during dry season, in West African dwarf sheep goats’ production systems was reviewed. For more sustainable agricultural systems, including expanding use locally produced available feedstuffs, FTL species with focus on Leucaena leucocephala, Gliricidia sepium, Enterolobium cyclocarpum represent an interesting provide dietary nitrogen improve feed digestibility, weight gain, retention, thus enhancing productivity. They also contain concentrations biologically active compounds nutraceutical value that assist slowing down infections parasitic nematodes gastrointestinal tract mitigating enteric methane emissions from these animals. crude protein tannin content ranged 16.20 26.79% 0.95 2.92%, respectively across species. Mean gain (g/day) 43.23 48.59 32.46 40.87, were reviewed for goats fed supplementary diets. Haematological serum biochemical variables monitored within permissible range healthy animals showed adequacy nutrient utilization review concluded combination excellent nutritive reported provides important opportunities goat feeding systems.
Язык: Английский
Процитировано
2