Revista Foco,
Год журнала:
2024,
Номер
17(2), С. e4452 - e4452
Опубликована: Фев. 19, 2024
Cinnamon
(Cinnamomum
sp)
has
been
used
as
a
spice
for
millennia,
offering
nutritional,
aromatic,
and
pharmaceutical
properties.
The
essential
oil
from
cinnamon
bark
predominantly
contains
cinnamaldehyde,
which
exhibits
applications
an
antioxidant,
anti-inflammatory,
antimicrobial,
wound-healing
agent.
These
characteristics
have
drawn
the
interest
of
industry,
seeking
to
identify
alternative
uses
this
compound
treatment
oral
diseases.
In
light
this,
present
study
aims
conduct
literature
review,
justifying
potential
presented
by
oil,
specifically
synthesis
new
pharmaceuticals
intended
dental
use.
International Journal of Molecular Sciences,
Год журнала:
2025,
Номер
26(1), С. 381 - 381
Опубликована: Янв. 4, 2025
Enterohemorrhagic
Escherichia
coli
(EHEC)
is
a
common
pathotype
of
E.
that
causes
numerous
outbreaks
foodborne
illnesses.
EHEC
zoonotic
pathogen
transmitted
from
animals
to
humans.
Ruminants,
particularly
cattle,
are
considered
important
reservoirs
for
virulent
strains.
Humans
can
become
infected
with
through
the
consumption
contaminated
food
and
water
or
direct
contact
O157:H7
one
most
commonly
reported
illnesses
in
developed
countries.
The
formation
attaching
effacing
(A/E)
lesions
on
intestinal
epithelium,
combined
Shiga
toxin
production,
hallmark
infection
lead
lethal
hemolytic–uremic
syndrome
(HUS).
For
phage-dependent
regulation
antibiotic
treatment
contraindicated,
as
it
may
exacerbate
limiting
therapeutic
options
supportive
care.
In
response
this
challenge
growing
threat
resistance,
phytochemicals
have
emerged
promising
antivirulence
agents.
These
plant-derived
compounds
target
bacterial
virulence
mechanisms
without
promoting
resistance.
Therefore,
aim
study
summarize
recent
knowledge
use
targeting
EHEC.
We
focused
molecular
basis
their
action,
principal
determinants
Journal of Applied Microbiology,
Год журнала:
2024,
Номер
135(4)
Опубликована: Март 12, 2024
To
evaluate
the
effect
of
silver
nanoparticles
alone
and
in
combination
with
Triclosan,
trans-cinnamaldehyde
against
Staphylococcus
aureus
Escherichia
coli
biofilms
on
sutures
to
improve
patients'
outcomes.
Organics,
Год журнала:
2024,
Номер
5(4), С. 395 - 428
Опубликована: Окт. 21, 2024
From
Egyptian
mummies
to
the
Chanel
N°
5
perfume,
aldehydes
have
been
used
for
a
long
time
and
continue
impact
our
senses
in
wide
range
of
perfumes,
foods,
beverages.
Aldehydes
represent
one
categories
volatile
organic
compounds
(VOCs),
which
are
categorized
as
chemicals
with
boiling
points
up
260
°C
can
be
found
indoor
environments
gaseous
phase.
Because
their
potential
or
known
hazardous
properties
humans,
World
Health
Organization
(WHO)-Europe
provided
some
guidelines
that
may
prevent
several
health
risks.
Indeed,
aldehydes,
reported
risky
retired
from
market,
such
butylphenyl
methylpropional
(BMHCA).
The
purpose
this
review
is
summarize
most
important
indoors
outdoors
analyse
depth
toxicological
aspects
these
compounds,
whose
presence
perfumes
often
underestimated.
In
addition,
ingredients’
synonyms
literature
same
compound
were
unified
order
simplify
identification.
Liver
fibrosis,
a
complex
process
resulting
from
most
chronic
liver
diseases,
remains
devoid
of
effective
treatments.
An
increasing
body
evidence
links
fibrosis
to
the
"gut-liver
axis",
with
disruptions
in
gut
microbiota-host
balance
emerging
as
critical
contributor
its
progression.
Cinnamaldehyde
(Cin),
natural
compound
antioxidant,
anti-inflammatory,
and
anticytotoxic
properties,
has
shown
potential
counteracting
hepatic
stellate
cell
(HSC)
activation.
Additionally,
Cin
been
promote
probiotics
intestine,
thereby
restoring
healthy
microbial
community.
These
characteristics
position
promising
candidate
for
treatment
through
modulation
gut-liver
axis.
In
this
study,
Vitamin
A
(Va)-formulated
Nanoemulsion
(Va-Cin@NM)
was
developed
enhance
physicochemical
stability
while
preserving
intestinal
homeostasis
facilitating
targeted
deposition.
bile
duct
ligation
(BDL)-induced
rats,
Va-Cin@NM
intervention
significantly
reduced
duct-like
structure
proliferation
collagen
deposition
liver.
effects
are
likely
attributed
restoration
microbiota,
increased
short-chain
fatty
acid
(SCFA)
concentrations,
improved
integrity.
Moreover,
suppressed
harmful
bacterial
populations
liver,
thus
mitigating
immune
injury
inflammatory
recruitment.
Consequently,
oxidative
stress
HSC
activation
were
attenuated.
Overall,
demonstrates
significant
nanotherapeutic
approach
by
modulating
