Evaluating Jordan's Antimicrobial Resistance National Action Plan (2018-2022) Implementation: Progress and Recommendations

Опубликована: Апрель 25, 2025

Background Antimicrobial resistance (AMR) is a pressing global public health challenge that requires coordinated multisectoral responses. In line with the Global Action Plan (GAP) on AMR, Jordan developed its first National (NAP) for 2018–2022 to guide efforts. This study aimed evaluate implementation of Jordan's AMR NAP, identify progress and challenges across five strategic objectives, suggest actionable recommendations strengthening future Methods The Center Disease Control (Jordan CDC) conducted comprehensive 'end-term evaluation' NAP 2018–2022. Data were collected from approximately seventy national stakeholders through workshop follow-up electronic communications. evaluation tool included sector-specific indicators aligned NAP's objectives. Descriptive statistical analysis was performed using SPSS determine rates human, animal, environmental sectors, applying One Health approach. Results revealed uneven notable achievements in rational use antimicrobials (69%) completion, mainly human sector. Infection prevention control (IPC) efforts reached (63%), while surveillance-related activities achieved (56%). Awareness-related reported limited (47%), no implemented under research innovation objective. Multisectoral collaboration limited, particularly animal sectors. Significant barriers absence unified communication strategy, lack dedicated funding, insufficient investment resources laboratories, disruptions caused by Coronavirus 2019 (COVID-19) pandemic. Conclusions Despite different areas, overall significant challenges, research, collaboration, integration. Future action should prioritize policy framework planning, emphasizing resource distribution, active participation all relevant systematic monitoring inform policymaking. Strengthening coordination between sectors essential achieving robust, Health-aligned response Jordan.

Язык: Английский

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Burden of Six Common Sexually Transmitted Infections Groups in North Africa and Middle East Region From 1990 to 2021: A Systematic Analysis of Global Burden of Diseases

Journal of Infection and Public Health, Год журнала: 2025, Номер unknown, С. 102793 - 102793

Опубликована: Апрель 1, 2025

Язык: Английский

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Using Culture Sensitivity Reports to Optimize Antimicrobial Therapy: Findings and Implications of Antimicrobial Stewardship Activity in a Hospital in Pakistan

Medicina, Год журнала: 2023, Номер 59(7), С. 1237 - 1237

Опубликована: Июль 2, 2023

Background: There are concerns with inappropriate prescribing of antibiotics in hospitals especially broad spectrum Pakistan and the subsequent impact on antimicrobial resistance rates. One recognized way to reduce is for empiric therapy be adjusted according result culture sensitivity reports. Objective: Using reports optimize antibiotic a teaching hospital Pakistan. Methods: A retrospective observational study was undertaken Ghurki Trust Teaching Hospital. total 465 positive cultures were taken from patients during period (May 2018 December 2018). The results pathogen identification susceptibility testing patient-infected sites assessed. Additional data collected patient's medical file. This included demographic data, sample type, causative microbe, treatment, whether or definitive treatment as well medicine costs. Antimicrobial assessed using World Health Organization's Defined Daily Dose methodology. Results: 497 isolates detected patient samples 32 had polymicrobes, which 309 g-negative rods 188 g-positive cocci. Out isolates, most common Gram-positive isolated Staphylococcus aureus (Methicillin-sensitive aureus) (125) (25.1%) Gram-negative Escherichia coli (140) (28.1%). Most gram-negative found resistant ampicillin co-amoxiclav. Acinetobacter baumannii carbapenems. bacteria showed maximum linezolid vancomycin. widely used cefoperazone plus sulbactam, ceftriaxone, amikacin, vancomycin, metronidazole whereas high use linezolid, clindamycin, meropenem, piperacillin + tazobactam seen treatment. Empiric 220 (71.1%) cases infections 134 (71.2%) infections. Compared therapy, there 13.8% reduction number average cost less than (8.2%) length hospitalization also decreased. Conclusions: Culture helped reduced utilization costs select appropriate We an urgent need implementing stewardship programs development guidelines unnecessary broad-spectrum antibiotics.

Язык: Английский

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Bacterial co-infections, secondary infections and antimicrobial use among hospitalized COVID-19 patients in the sixth wave in Pakistan: findings and implications

Expert Review of Anti-infective Therapy, Год журнала: 2023, Номер 22(4), С. 229 - 240

Опубликована: Дек. 26, 2023

Previous studies in Pakistan have shown considerable over prescribing of antibiotics patients hospitalized with COVID-19 despite very low prevalence bacterial infections. Irrational use will worsen antimicrobial resistance (AMR).

Язык: Английский

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Quality Indicators of Antimicrobials Prescribing in Iraq: A Scoping Review

Al-Rafidain Journal of Medical Sciences ( ISSN 2789-3219 ), Год журнала: 2024, Номер 7(1), С. 221 - 226

Опубликована: Сен. 7, 2024

Background: Antimicrobial overconsumption is a global public health concern, particularly in the Middle East, where illnesses and antibiotic use are on increase. resistance associated with excessive usage. As Eastern country, Iraq provides suitable baseline for situating it amid its neighbors. We quality indicators to reliably identify bad practice recommend updated prescribing practices hospitalized patients. Objectives: To compare antimicrobial metrics Iraqi hospitals those nations. Methods: conducted literature review using point prevalence survey assess inappropriateness of usage East countries after evaluating from sources such as Scopus, Web Science, PubMed, EBSCO. examine scenario, we used four primary indicators: guidelines compliance, stop/review note documentation, parenteral administration, selection targeted antibios. Results: According study, Iraq's guideline availability ranged 0% 7%, which was lower than Jordan's optimum 95.8%. The rate documentation approximately 0.4%, maximum 72% UAE; only 1.2% prescriptions were antibiotics, higher Iran's 0%. Regarding reported that 89.9% antibiotics injectable, consistent most comparable nations (74%-100%). Conclusions: In hospitals, antimicrobials inappropriately. An immediate effort necessary update national records, ongoing follow-up by regular surveys.

Язык: Английский

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Antibiotic point prevalence survey and antimicrobial resistance in hospitalized patients across Peruvian reference hospitals

Journal of Infection and Public Health, Год журнала: 2023, Номер 16, С. 52 - 60

Опубликована: Ноя. 1, 2023

Peru reports higher levels than other countries in Latin America of resistance to antimicrobials among Gram-positive and Gram-negative bacteria, however data on antibiotic use are scarce. This study aims estimate the prevalence quality prescription hospitalized patients determine susceptibility rates bacteria causing key bacterial infections. We carried out a point survey at ten public hospitals nine regions Peru. Data was collected from during 3-week period, with details about use, patient information, antimicrobial susceptibility. 1620 charts were reviewed; 924 cases antibiotics prescribed (57.0%, range 45.9-78.9%). Most (74.2%) as empirical treatment, only 4.4% targeted treatment. For 9.5% reason for unknown. Cephalosporins most (30.0%), followed by carbapenems (11.3%). Ninety-four blood cultures positive growth, 48.8% Staphylococcus aureus methicillin-resistant, Escherichia coli Klebsiella pneumoniae, 51.7% 72.7% resistant third-generation cephalosporins (3GC), 3.4% 18.2% carbapenems, respectively. Among isolated urine (n = 639), 43.9% E. 49.2% K. pneumoniae 3GC, 0.9% 3.2% meropenem. The overall proportion receiving different high, small frequently antibiotics, reflecting high against 3GC Enterobacterales urine.

Язык: Английский

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Point Prevalence Survey of Antimicrobial Use and Resistance during the COVID-19 Era among Hospitals in Saudi Arabia and the Implications

Antibiotics, Год журнала: 2023, Номер 12(11), С. 1609 - 1609

Опубликована: Ноя. 9, 2023

The inappropriate prescribing of antimicrobials increases antimicrobial resistance (AMR), which poses an appreciable threat to public health, increasing morbidity and mortality. Inappropriate includes their in patients hospitalized with COVID-19, despite limited evidence bacterial infections or coinfections. Knowledge current utilization Saudi Arabia is currently limited. Consequently, the objective this study was document patterns among hospitals during COVID-19 pandemic. This included without who were admitted five Makkah, Arabia. Data gathered using Global PPS methodology analyzed descriptive statistics. Out 897 patients, 518 treated antibiotics (57.7%), average 1.9 per patient. There 174 culture reports collected, representing 36.5% all cases. most common indication for use community-acquired infections, accounting 61.4% 'Watch' commonly prescribed antibiotics, cephalosporins carbapenems 38.7% prescribed, followed by penicillins (23.2%). Notably, Piperacillin/Tazobactam Azithromycin at relatively higher rates patients. These findings highlight need continuous efforts optimize rational through instigating appropriate stewardship programs and, as a result, reduce AMR country.

Язык: Английский

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A longitudinal point prevalence survey of antimicrobial use and resistance in tertiary care hospitals in Kerman: results from the national Iranian multicenter point prevalence survey of antimicrobials in 2021

BMC Infectious Diseases, Год журнала: 2024, Номер 24(1)

Опубликована: Ноя. 14, 2024

The Global Point Prevalence Survey (PPS) of antimicrobial consumption and resistance has been widely undertaken to combat the global threat (AMR). This study was conducted in alignment with Global-PPS three tertiary care hospitals Kerman, Iran, evaluate patterns. from January 2020 2021 Afzalipour, Shafa, Shahid Bahonar Hospitals. Data were collected using standardized method at different points throughout year minimize bias. Information on prescriptions, primary diagnosis, prophylaxis, therapy indications, treatment type documented. Antimicrobial prevalence calculated total number admitted patients as denominator those regimens numerator. point adult wards 65.6% Afzalipour Hospital, 42.3% Shafa 78.7% Hospital. Non-penicillin beta-lactams, macrolides, lincosamides, streptogramins most frequently prescribed antibiotic classes. Approximately 80% prescriptions had explicit reasons documented, targeted rates varied between 7.7% 44.8% across hospitals. Kerman's exceeded national levels, indicating an urgent need for interventions promote rational use. Infection control committees must implement rigorous monitoring measures reduce resistance. Ongoing surveillance are essential curb rising region.

Язык: Английский

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Antimicrobial Use Among Hospitalized Neonates and Children; Findings and Implications from a Comprehensive Point Prevalence Survey Among General Tertiary Hospitals in Pakistan

Infection and Drug Resistance, Год журнала: 2024, Номер Volume 17, С. 5411 - 5428

Опубликована: Дек. 1, 2024

Antimicrobial resistance is a global health crisis exacerbated by excessive and inappropriate use of antibiotics, especially among low- middle-income countries including Pakistan. The paediatric population key area in view their vulnerability prescribing antibiotics Consequently, there an urgent need to robustly assess antimicrobial hospitalized neonates children tertiary hospitals Pakistan as they are generally the training centres for new physicians subsequently treating children.

Язык: Английский

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Paediatricians’ knowledge, perceptions, preparedness and involvement towards paediatric antimicrobial stewardship in Pakistan: findings and the implications

JAC-Antimicrobial Resistance, Год журнала: 2024, Номер 6(6)

Опубликована: Окт. 30, 2024

Antibiotics are frequently prescribed for neonates and children. However, this can be excessive with inappropriate prescribing leading to increased antimicrobial resistance (AMR). Paediatricians key initiators of antibiotics. Consequently, their awareness, perceptions, readiness potential barriers towards hospital-based stewardship programmes considerable importance, especially in Pakistan high rates AMR.

Язык: Английский

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