Application of Response Surface Methodology to Design and Optimize Purification of Acetone or Aqueous Acetone Extracts of Hop Cones (Humulus lupulus L.) Using Superparamagnetic Iron Oxide Nanoparticles for Xanthohumol Isolation DOI Open Access

Natalia Żuk,

Sylwia Pasieczna‐Patkowska, Jolanta Flieger

и другие.

Materials, Год журнала: 2024, Номер 17(19), С. 4827 - 4827

Опубликована: Сен. 30, 2024

Iron oxide nanoparticles (IONPs) are an ideal sorbent for magnetic dispersion extraction due to their superparamagnetic properties and developed active surface. This work aims use IONPs, obtained by chemical co-precipitation, purify 100% acetone 50% extracts from hop cones (Humulus lupulus L.) ultrasonic-assisted solvent extraction. The were purified bitter acids (i.e., humulones, lupulones) isolate xanthohumol. sorption conditions optimized depending on the composition of mixture, specifically mass IONPs time needed achieve effective using response surface methodology (RSM). An analysis variance (ANOVA) was performed assess adequacy model, a good agreement found between experimental data proposed model. polynomial equation describing model is highly significant (p < 0.05), with precision Adeq (above 4). indicates usefulness regression prediction in design. final products purification contain 40.58 ± 2.84 µg mL-1 57.64 0.83 xanthohumol, respectively. extract provides more favorable smaller amount required higher recovery development reliable multivariate allowed optimization process, resulting high-purity xanthohumol natural sources.

Язык: Английский

Application of Fourier Transform Infrared (FTIR) Spectroscopy in Characterization of Green Synthesized Nanoparticles DOI Creative Commons
Sylwia Pasieczna‐Patkowska, Marcin Cichy, Jolanta Flieger

и другие.

Molecules, Год журнала: 2025, Номер 30(3), С. 684 - 684

Опубликована: Фев. 4, 2025

The fundamental principle of Fourier Transform Infrared (FTIR) spectroscopy is based on the vibration and rotation atoms, it has become a universal widely used spectral methodology for detection internal molecular structures in diverse range fields. A considerable number review articles pertaining to applications FTIR have been published recent years. Nevertheless, comprehensive summary application nanoparticles’ (NPs’) green synthesis yet be presented. In present paper, we propose series case studies that demonstrate analysis metal oxide NPs synthesized using processes. Furthermore, presented position functional group bands spectra are responsible reduction, capping stabilization NPs. this review, explore advantages limitations methodologies overcoming these challenges. We also potential solutions complex spectra. intended serve as compendium information researchers engaged field NPs, utilizing research tool.

Язык: Английский

Процитировано

6

Sustainable Synthesis of Novel Green-Based Nanoparticles for Therapeutic Interventions and Environmental Remediation DOI
Swati Singh, Harshita Tiwari, Ashish Verma

и другие.

ACS Synthetic Biology, Год журнала: 2024, Номер 13(7), С. 1994 - 2007

Опубликована: Июнь 20, 2024

The advancement in nanotechnology has completely revolutionized various fields, including pharmaceutical sciences, and streamlined the potential therapeutic of many diseases that endanger human life. synthesis green nanoparticles by biological processes is an aspect newly emerging scientific field known as "green nanotechnology". Due to their safe, eco-friendly, nontoxic nature, tools are better suited produce between 1 100 nm. Nanoformulation different types been made possible using production techniques commercially feasible novel precursors, such seed extracts, algae, fungi, act potent reducing, capping, stabilizing agents. In addition this, biofunctionalization also broadened its horizon environmental remediation innovations wound healing, antimicrobial, anticancer, nano biosensing. However, major challenge pertaining agglomeration may alter surface topology, which can affect physiology, thereby contributing system toxicity. Therefore, a thorough grasp nanoparticle toxicity biocompatibility required harness applications therapeutics.

Язык: Английский

Процитировано

13

Purification of Spent Hop Cone (Humulus lupulus L.) Extract with Xanthohumol Using Mesoporous Superparamagnetic Iron Oxide Nanoparticles DOI Creative Commons

Natalia Żuk,

Sylwia Pasieczna‐Patkowska, Ewelina Grabias

и другие.

Antioxidants, Год журнала: 2025, Номер 14(3), С. 314 - 314

Опубликована: Март 5, 2025

(1) Background: Over 90% of hop crops are currently used in beer production, with a small part the cosmetics and pharmaceutical industries. Spent hops as waste product contain one strongest antioxidants, xanthohumol. The aim study was to purify spent extracts by magnetic dispersive extraction using iron oxide nanoparticles (IONP) obtain pure xanthohumol; (2) Methods: extract from obtained after supercritical carbon dioxide prepared ultrasound-assisted utilizing different solvents, i.e., ethyl acetate, propanol, acetone, 80% methanol, acetate-methanol (1:1, v/v), propanol-methanol v/v). hydrodynamic diameters zeta potential IONPs before incubation were measured dynamic light scattering (DLS). analyzed reversed-phase high-performance liquid chromatography (HPLC). Isolated xanthohumol identified based on DAD spectrum range 200-600 nm Fourier transform infrared spectroscopy/attenuated total reflectance (FT-IR/ATR); antioxidant activity assessed SNPAC (Silver Nanoparticle Antioxidant Capacity), DPPH (2,2-diphenyl-1-picrylhydrazyl radical), FRAP (Ferric Reducing Power) assays, well phenolic content (TPC) flavonoid (TFC). (3) Results: amount added IONPs, kind solvent, contact time optimized. We found that MeOH (865 µg IONPs/g hops) at room temperature for 48 h contains 74.61% initial content, providing final concentration 43 mL-1. (4) Conclusions: proposed method allows purification obtaining product, namely xanthohumol, wide practical applications medicine, pharmacy, cosmetics, agriculture. This is clear evidence usefulness IONP an effective sorbent. use residues brewing industry, biomass cones valuable substance.

Язык: Английский

Процитировано

1

Selective Removal of Chlorophyll and Isolation of Lutein from Plant Extracts Using Magnetic Solid Phase Extraction with Iron Oxide Nanoparticles DOI Open Access
Jolanta Flieger,

Natalia Żuk,

Sylwia Pasieczna‐Patkowska

и другие.

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(6), С. 3152 - 3152

Опубликована: Март 9, 2024

In recent years, there has been a growing interest in plant pigments as readily available nutraceuticals. Photosynthetic pigments, specifically chlorophylls and carotenoids, renowned for their non-toxic antioxidant properties, are increasingly finding applications beyond health-promoting attributes. Consequently, is an ongoing need cost-effective methods of isolation. This study employs co-precipitation method to synthesize magnetic iron oxide nanoparticles. Scanning electron microscopy (SEM) coupled with energy dispersive spectrometry (EDS) confirms that aqueous environment oxidizing conditions yield nanosized particle sizes ranging from 80 140 nm. X-ray photoelectron spectroscopy (XPS) spectra indicate the presence hydrous FeO(OH) on surface oxide. The Brunauer–Emmett–Teller (BET) area obtained nanomaterial was 151.4 m2 g−1, total pore volumes pores 0.25 cm3 g−1 STP. material, designated nanoparticles (IONPs), serves adsorbent solid phase extraction (MSPE) isolation photosynthetic (chlorophyll a, lutein) extracts higher green plants (Mentha piperita L., Urtica dioica L.). Sorption chlorophyll onto confirmed using UV–vis spectroscopy, Fourier transform infrared photoacoustic (FT-IR/PAS), high-performance liquid chromatography (HPLC). Selective sorption requires minimum 3 g IONPs per 12 mg acetone solvent, dependent storage time 48 h. Extended contact extract, i.e., 72 h, ensures elimination remaining components except lutein, spectral purity 98%, recovered over 90% efficiency. mechanism removal relies interaction pigment’s carbonyl (C=O) groups hydroxyl (–OH) groups. Based molecular dynamics (MD) simulations, it proven selective adsorption also influenced by more favorable dispersion interactions between comparison other solutes. An significantly promotes pigments; however, results complete loss selectivity.

Язык: Английский

Процитировано

4

Biosynthesis Optimization of Antibacterial-Magnetic Iron Oxide Nanoparticles from Bacillus megaterium DOI

Sajedeh Hajiali,

Sara Daneshjou, Somayeh Daneshjoo

и другие.

Biological Trace Element Research, Год журнала: 2024, Номер unknown

Опубликована: Апрель 12, 2024

Язык: Английский

Процитировано

4

Surfactant functionalized iron oxide nanoparticles: Multifunctional engineered nanomaterial with boosted antimicrobial, photocatalytic and antioxidant performance DOI

Kahkashan R. Shaikh,

Sakina M. Mir,

Vrushabh Manoj Khandelwal

и другие.

Inorganic Chemistry Communications, Год журнала: 2025, Номер unknown, С. 114233 - 114233

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

Biosynthesis of Phytochemical-Adorned Green Iron Oxide Nanoparticles Via Astragalus anisacanthus Extract and Evaluation of Biological Potentials DOI
Rafi Ullah,

Javed Iqbal,

Bilal Haider Abbasi

и другие.

Journal of Inorganic and Organometallic Polymers and Materials, Год журнала: 2025, Номер unknown

Опубликована: Апрель 10, 2025

Язык: Английский

Процитировано

0

Optimization of Cyanocobalamin (Vitamin B12) Sorption onto Mesoporous Superparamagnetic Iron Oxide Nanoparticles DOI Creative Commons
Jolanta Flieger,

Natalia Żuk,

Sylwia Pasieczna‐Patkowska

и другие.

Molecules, Год журнала: 2024, Номер 29(9), С. 2094 - 2094

Опубликована: Май 1, 2024

The techniques used to detect and quantify cyanocobalamin (vitamin B12) vary considerably in terms of detection sensitivity, from the most sensitive, based on radioisotopes mass spectrometry (MS) with limits (LOD) fg mL−1, fluorescence (FL) surface plasmon resonance (SPR) biosensors LOD values range a few µg mL−1. For accurate quantification an analyte present at trace levels complex biological matrices, selective separation enrichment step is required overcome matrix interferences ensure sufficient sensitivity. In this study, iron oxide magnetic nanoparticles (IONPs) were for extraction initial preconcentration B12). dependence magnetization H-field (hysteresis loop), no coercivity remanence found 300 K, indicating superparamagnetic properties tested IONPs. Perfluorinated acids as amphiphilic agents allow sorption onto FT-IR/ATR spectroscopy was confirm influence addition homologous series perfluorinated such trifluoroacetic acid (TFAA), heptafluorobutyric (HFBA), trichloroacetic (TCAA) mixture considering their type, mass, time effective sorption. adsorption kinetics isotherm, described by Freundlich Langmuir equations, analyzed. maximum capacity (qm) exceeded 6 mg g−1 8.9 7.7 HFBA TCAA, respectively, efficient additives. After desorption process using aqueous KH2PO4 solution, sample finally analyzed spectrophotometrically chromatographically. IONP-based method successfully applied isolation human urine samples. results showed that developed approach simple, cheap, accurate, determination traces matrices.

Язык: Английский

Процитировано

2

Application of Response Surface Methodology to Design and Optimize Purification of Acetone or Aqueous Acetone Extracts of Hop Cones (Humulus lupulus L.) Using Superparamagnetic Iron Oxide Nanoparticles for Xanthohumol Isolation DOI Open Access

Natalia Żuk,

Sylwia Pasieczna‐Patkowska, Jolanta Flieger

и другие.

Materials, Год журнала: 2024, Номер 17(19), С. 4827 - 4827

Опубликована: Сен. 30, 2024

Iron oxide nanoparticles (IONPs) are an ideal sorbent for magnetic dispersion extraction due to their superparamagnetic properties and developed active surface. This work aims use IONPs, obtained by chemical co-precipitation, purify 100% acetone 50% extracts from hop cones (Humulus lupulus L.) ultrasonic-assisted solvent extraction. The were purified bitter acids (i.e., humulones, lupulones) isolate xanthohumol. sorption conditions optimized depending on the composition of mixture, specifically mass IONPs time needed achieve effective using response surface methodology (RSM). An analysis variance (ANOVA) was performed assess adequacy model, a good agreement found between experimental data proposed model. polynomial equation describing model is highly significant (p < 0.05), with precision Adeq (above 4). indicates usefulness regression prediction in design. final products purification contain 40.58 ± 2.84 µg mL-1 57.64 0.83 xanthohumol, respectively. extract provides more favorable smaller amount required higher recovery development reliable multivariate allowed optimization process, resulting high-purity xanthohumol natural sources.

Язык: Английский

Процитировано

2