Pharmaceuticals,
Год журнала:
2023,
Номер
16(9), С. 1202 - 1202
Опубликована: Авг. 23, 2023
Inflammation
plays
a
pivotal
role
in
the
resolution
of
infection
or
tissue
damage.
In
addition,
inflammation
is
considered
hallmark
aging,
which
turn
compromises
wound
healing.
Thymbra
capitata
an
aromatic
plant,
whose
infusion
traditionally
used
as
anti-inflammatory
and
wound-healing
agent.
this
study,
T.
was
prepared
characterized
by
HPLC-PDA-ESI-MSn
its
safety
profile
determined
resazurin
metabolic
assay.
The
potential
revealed
lipopolysaccharide
(LPS)-stimulated
macrophages
assessing
nitric
oxide
(NO)
release
levels
inducible
synthase
(iNOS)
interleukin-1β
pro-form
(pro-IL-1β).
Wound-healing
capacity
using
scratch
activity
senescence-associated
β-galactosidase
to
unveil
anti-senescent
potential,
along
with
nuclear
accumulation
yH2AX
p21
levels.
antiradical
assessed
DPPH
ABTS
scavenging
assays.
contains
predominantly
rosmarinic
acid
salvianolic
acids.
extract
decreased
NO,
iNOS,
pro-IL-1β
Interestingly,
promoted
healing
activity,
well
present
work
highlights
strong
antiradical,
anti-inflammatory,
capacities,
corroborating
traditional
uses
ascribed
plant.
We
have
described,
for
first
time
extract,
properties.
Journal of Essential Oil Bearing Plants,
Год журнала:
2024,
Номер
27(2), С. 498 - 509
Опубликована: Фев. 22, 2024
AbstractImmortelle
(Helichrysum
italicum)
essential
oil
is
one
of
the
most
valuable
oils
with
its
commercial
importance
and
favorable
characteristic
properties
in
various
cosmetic
products
food
products.
Current
research
performed
a
comprehensive
characterization
Immortelle
using
powerful
robust
analytical
techniques.
The
relative
volatile
composition
from
Turkey
was
determined
by
GC-MS
(gas
chromatography-mass
spectrometry)
technique.
Thirty-eight
compounds
were
identified.
Average
total
phenolic
content
DPPH
radical
scavenging
activities
(IC50)
as
54.24
mg
GAE/mL
0.27
mg/ml,
respectively.
FTIR
Raman
spectroscopy
fingerprints
for
chemical
characterization.
thermal
profile
obtained
DSC
(differential
scanning
calorimetry)
analysis.
(12.5
μg/mL)
inhibited
growth
Caco
2
adenocarcinoma
cells
at
ratio
48%
without
any
deterioration
healthy
L929
fibroblast
according
to
cytotoxicity
analyses.Keywords:
Helichrysum
italicum
(Immortelle)
oilChemical
fingerprintingAntioxidantVolatile
compositionAnticarcinogenicDSCFTIRRamanGC-MS
Marine Drugs,
Год журнала:
2023,
Номер
21(7), С. 380 - 380
Опубликована: Июнь 27, 2023
Bioactive
extracts
are
often
the
target
fractions
in
bioprospecting,
and
halophyte
plants
could
provide
a
potential
source
of
feedstock
for
high-value
applications
as
part
integrated
biorefineries.
Tripolium
pannonicum
(Jacq.)
Dobrocz.
(sea
aster)
Crithmum
maritimum
L.
fennel)
edible
suggested
biosaline
halophyte-based
agriculture.
After
food
production
harvesting
fresh
leaves
food,
inedible
plant
be
utilized
to
produce
rich
bioactive
phytochemicals
maximize
application
increase
economic
feasibility
biomass
processing
bioenergy.
This
study
analyzed
juice
from
screw-pressed
sea
aster
fennel
their
different
phenolic
compounds
pigment
concentrations.
Antioxidant
enzyme
inhibition
activities
were
also
tested
vitro.
Extracts
had
contents
up
45.2
mgGAE/gDM
64.7
mgGAE/gDM,
respectively,
exhibited
>70%
antioxidant
activity
several
assays.
Ethanol
showed
against
acetylcholinesterase
>50%
tyrosinase
α-glucosidase.
Therefore,
these
species
can
seen
feedstocks
further
investigations.
Plants,
Год журнала:
2024,
Номер
13(4), С. 550 - 550
Опубликована: Фев. 17, 2024
Crithmum
maritimum
L.
is
a
perennial
halophyte
plant
that
medicinal
herb
known
by
people
from
different
cultures
since
ancient
times.
However,
the
therapeutic
potential
of
this
has
not
been
completely
investigated,
and
scientific
data
on
it
are
limited.
The
purpose
present
study
was
to
estimate
chemical
composition
essential
oil
(EO)
obtained
aerial
parts
growing
wild
in
Bulgaria,
as
well
histolocalization
secretory
structures
for
synthesis
accumulation
volatile
oils.
results
EO
Bulgarian
provide
an
opportunity
reveal
future
applications
various
fields,
such
medicine,
pharmacy,
agriculture,
food,
cosmetic
industry.
Gas
chromatography
with
mass
spectrometry
performed
assess
profile
isolated
EO.
phenylpropanoid
dillapiole
identified
major
compound
EO,
accounting
34.09%
total
Monoterpene
hydrocarbons
represented
62.07%
composition.
γ-Terpinene,
D-limonene,
β-pinene
were
most
abundant
monoterpene
In
addition,
histochemical
localization
stem
leaves
carried
out.
located
cortical
region
mesophyll
tissues
form
ducts.
analysis
confirmed
lipophilic
nature
secretion
duct
cells.
This
first
report
related
Furthermore,
our
indicate
some
possibilities
evaluation
activity
species
outline
its
agent.
Also,
studied
prominent
be
used
biopesticide,
which
environmentally
friendly
option
compared
standard
pesticides.
Journal of Chemical Technology and Metallurgy,
Год журнала:
2024,
Номер
59(3), С. 549 - 557
Опубликована: Май 7, 2024
Natural
ingredients
rich
in
antioxidants
and
polyphenols
the
forme
of
extracts,
essential
oils,
organic
acids
have
been
used
production
different
cosmetic
products.
In
development
new
compositions,
or
improvement
products
already
implemented
production,
evaluation
user
is
great
importance,
as
it
directly
affects
demand
for
a
given
product.
The
present
study
aimed
to
produce
phytocosmetic
creams
based
on
stearic
acid
with
extracts
dry
flower
fruit
juice
Sambucus
nigra
L.
(S.
nigra)
investigatein
parallel
their
potential
substitutes
conventional
preservatives.
obtained
were
determined
minimum
inhibitory,
bactericidal
activity
using
three
bacterial
strains
(Pseudomonas
aeruginosa
ATCC
27853,
Staphylococcus
aureus
ATCC25923,
Bacillus
subtilis
6633).
addition,
antibacterial
effect
against
Escherichia
coli
(BW
28357)
was
determined.
our
experiments
we
found
that
addition
dried
elderberry
from
S.
emulsion
does
not
disturb
compositional
system.
conclusion,
according
results,
flowers
fruitsare
appropriate
use
emulsions
demonstated
antioxidant
stability
properties.
Jurnal Ilmiah Farmasi Farmasyifa,
Год журнала:
2024,
Номер
7(2), С. 228 - 249
Опубликована: Июль 31, 2024
Tanaman
krokot
(Portulaca
oleracea
Linn.)
kaya
akan
senyawa
fenolik
yang
dapat
digunakan
untuk
mengatasi
sindroma
metabolik,
mendapatkan
berkhasiat
dari
tanaman
diperlukan
suatu
metode
ekstraksi,
namun
demikian
belum
ada
literatur
menguji
pengaruh
pemilihan
ekstraksi
infusa
vs
dekokta
terhadap
perolehan
kadar
total
krokot.
Penelitian
ini
bertujuan
mengetahui
Metode
dan
dilakukan
dengan
menggunakan
pelarut
air
1:10
b/v
(simplisia/pelarut)
pada
90°C.
Pada
wadah
tertutup
rapat
selama
15
menit,
sedangkan
esktraksi
hingga
volume
larutan
berkurang
setengahnya.
Penetapan
secara
spektrofotometrik
reagen
folin-ciocalteu
750
nm.
Pemilihan
konvensional
berpengaruh
signifikan
sig.
(2-tailed)
<
0.05
tamanan
Portulaca
Linn.
lebih
efektif
mengekstraksi
krokok,
menghasilkan
sebesar
377.60
±
2.44
mgGAE/g
ekstrak
kering
jika
dibandingkan
hanya
121.33
1.16
kering.
Research Journal of Pharmacy and Technology,
Год журнала:
2024,
Номер
unknown, С. 5515 - 5524
Опубликована: Ноя. 18, 2024
This
study
involved
the
investigation
of
polyphenol
and
flavonoid
content,
antioxidant
antimicrobial
potential
Hyoscyamus
albus
extracts.
Four
sub-fractions
were
obtained
by
successive
extraction
using
methanol,
chloroform,
ethyl
acetate.
The
extracts'
yields
counted
total
phenolic
(TPC)
content
(TFC)
assessed
via
spectrophotometric
methods.
activity
was
investigated
DPPH
test,
Total
Antioxidant
Capacity
(TAC),
Hydroxyl
radical
scavenging
potency
β-Carotene/linoleic
acid
bleaching
assay.
valued
against
08
strains
pathogenic
bacteria
yeast.
results
revealed
that
CrE
yielded
highest
extracted
value
(13,34%)
lowest
percentage
yield
EAE
(1.46%).
Interestingly,
gave
higher
amounts
polyphenols
(186.55
mg
GAEq/gE),
whereas
ChE
showed
(45.19mg
GAEq/gE).
Notably,
both
fractions
contained
levels
flavonoids,
correlating
with
their
activity.
Specifically,
displayed
(p<0.001)
IC50
21μg/ml
strongest
capacity
(EC50
=
50μg/ml).
While
is
regarded
as
an
excellent
OH
quencher
a
weaker
close
to
synthetic
reference
standard
(p<0.001).
However,
greater
inhibition
β-carotene
impeded
linoleic
oxidation.
Furthermore,
tested
extracts
exhibited
different
degrees
only
extract
proved
effective
yeast
(Candida
albicans).
current
confirmed
important
action,
well
significant
effects
These
findings
firmly
underpin
traditional
applications
this
herb
for
treating
ailments
infection,
could
in
fact
be
source
natural
antioxidant,
antibacterial
compounds.
Pharmaceuticals,
Год журнала:
2023,
Номер
16(9), С. 1202 - 1202
Опубликована: Авг. 23, 2023
Inflammation
plays
a
pivotal
role
in
the
resolution
of
infection
or
tissue
damage.
In
addition,
inflammation
is
considered
hallmark
aging,
which
turn
compromises
wound
healing.
Thymbra
capitata
an
aromatic
plant,
whose
infusion
traditionally
used
as
anti-inflammatory
and
wound-healing
agent.
this
study,
T.
was
prepared
characterized
by
HPLC-PDA-ESI-MSn
its
safety
profile
determined
resazurin
metabolic
assay.
The
potential
revealed
lipopolysaccharide
(LPS)-stimulated
macrophages
assessing
nitric
oxide
(NO)
release
levels
inducible
synthase
(iNOS)
interleukin-1β
pro-form
(pro-IL-1β).
Wound-healing
capacity
using
scratch
activity
senescence-associated
β-galactosidase
to
unveil
anti-senescent
potential,
along
with
nuclear
accumulation
yH2AX
p21
levels.
antiradical
assessed
DPPH
ABTS
scavenging
assays.
contains
predominantly
rosmarinic
acid
salvianolic
acids.
extract
decreased
NO,
iNOS,
pro-IL-1β
Interestingly,
promoted
healing
activity,
well
present
work
highlights
strong
antiradical,
anti-inflammatory,
capacities,
corroborating
traditional
uses
ascribed
plant.
We
have
described,
for
first
time
extract,
properties.
