Molecules,
Год журнала:
2024,
Номер
29(9), С. 2014 - 2014
Опубликована: Апрель 27, 2024
Polyphenols
are
ubiquitous
plant
metabolites
that
demonstrate
biological
activities
essential
to
plant–environment
interactions.
They
of
interest
food
consumers,
as
well
the
food,
pharmaceutical
and
cosmetic
industry.
The
class
comprises
both
widespread
(chlorogenic
acids,
luteolin,
quercetin)
unique
compounds
diverse
chemical
structures
but
common
biosynthetic
origin.
next
sesquiterpenoids
regarded
major
Inuleae-Inulinae
responsible
for
pharmacological
activity
medicinal
plants
from
subtribe
(Blumea
spp.,
Dittrichia
Inula
Pulicaria
spp.
others).
Recent
decades
have
brought
a
rapid
development
molecular
analytical
techniques
which
resulted
in
better
understanding
taxonomic
relationships
within
Inuleae
tribe
plethora
data
concerning
constituents
Inuleae-Inulinae.
current
taxonomical
classification
has
introduced
changes
well-established
botanical
names
rearranged
genera
based
on
genetic
studies.
newly
created
together
with
earlier
phytochemical
studies
may
provide
some
complementary
information
biochemical
subtribe.
Moreover,
they
at
least
partly
explain
preparations
traditionally
used
therapy.
review
aimed
systematize
knowledge
polyphenols
Inulae-Inulinae.
Chemistry & Biodiversity,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 28, 2024
Abstract
Platycladus
orientalis
leaves
are
widely
used
in
traditional
medicine
to
treat
different
ailments.
In
the
present
study,
volatile
constituents
were
obtained
by
n
‐hexane
extraction
and
hydrodistillation.
Comprehensive
metabolomic
profiling
was
performed
using
GC‐MS
analysis.
Furthermore,
vitro
antioxidant
potential
enzyme‐inhibitory
activity
assessed
supported
silico
profiling.
Results
revealed
predominance
of
monoterpene
hydrocarbons
hydrodistilled
oil
(42.30
%)
followed
oxygenated
sesquiterpenes
(32.10
%);
with
cedrol
as
main
component.
Diterpenoids
(49.70
sesquiterpene
(13.43
major
components
extract;
vulgarol
A,
a
diterpene
alcohol,
constituent.
The
demonstrated
significantly
higher
across
all
assays,
including
ABTS
DDPH
scavenging
activity,
CUPRAC,
FRAP
assays.
However,
extract
broad
inhibitory
effects
against
butyrylcholinesterase,
tyrosinase,
α
‐amylase,
‐glucosidase
enzymes,
molecular
docking
study
predictive
ADME
Therefore,
it
may
be
concluded
that
is
viable
option
for
treating
dysregulated
enzyme
conditions.
addition,
use
pharmaceutical
industries
management
oxidative
stress
can
inferred.
These
results
warrant
further
studies
validate
therapeutic
extract.
Journal of Food Quality,
Год журнала:
2024,
Номер
2024(1)
Опубликована: Янв. 1, 2024
Due
to
inadequate
treatment,
diabetes
mellitus,
which
is
characterized
by
hyperglycemia,
a
global
health
challenge
that
requires
creative
management
techniques.
This
study
explores
the
therapeutic
potential
of
Abelmoschus
esculentus
L.
Moench
fruit
extracts
in
diabetes,
offering
an
ample
approach
includes
phytochemical
analysis,
qualitative
and
quantitative
assessments,
antidiabetic
efficacy,
antioxidant
potential,
vivo
vitro
investigations.
Thin‐layer
chromatography
(TLC),
high‐performance
liquid
(HPLC),
gas
chromatography–mass
spectrometry
(GC–MS)
were
utilized
disclose
profile
extracts,
indicated
diverse
range
bioactive
compounds.
Four
polyphenolic
compounds
including
chlorogenic
acid,
quercetin,
rutin,
morin
confirmed
HPLC
fingerprinting,
with
rutin
being
most
prevalent.
Qualitative
analysis
reveals
presence
carbohydrates,
emodin,
terpenoids,
lignin,
glycosides,
anthraquinones,
while
indicating
absence
amino
acids,
anthocyanins,
phlobatannins,
lactones,
leucoanthocyanins.
Quantitative
total
phenolic,
tannin,
flavonoid.
In
assessments
demonstrate
ability
inhibit
alpha
amylase.
Radical
scavenging
activities
evaluated
through
DPPH
assay,
underscoring
their
capacity
high
effect
methanol
extracts.
Additionally,
extract
decreased
blood
glucose
level
Type
2
diabetic
mice.
Notably,
test
samples
stabilized
levels,
reversed
deviations
parameters,
biochemistry,
regulated
organ
weight.
Based
on
its
effects,
as
well
positive
effects
physiology
mice,
A.
emerges
important
nutraceutical
vegetable.
As
vegetable,
it
holds
promise
for
management.
can
be
incorporated
into
dietary
interventions
individuals
harnessing
natural
properties.
Our
findings
validate
traditional
use
green
therapeutics.
conclusion,
valuable
ally
fight
against
bridging
gap
between
ancient
wisdom
modern
science.
Further
research
practical
implementation
are
warranted
fully
realize
potential.
Molecules,
Год журнала:
2024,
Номер
29(9), С. 2014 - 2014
Опубликована: Апрель 27, 2024
Polyphenols
are
ubiquitous
plant
metabolites
that
demonstrate
biological
activities
essential
to
plant–environment
interactions.
They
of
interest
food
consumers,
as
well
the
food,
pharmaceutical
and
cosmetic
industry.
The
class
comprises
both
widespread
(chlorogenic
acids,
luteolin,
quercetin)
unique
compounds
diverse
chemical
structures
but
common
biosynthetic
origin.
next
sesquiterpenoids
regarded
major
Inuleae-Inulinae
responsible
for
pharmacological
activity
medicinal
plants
from
subtribe
(Blumea
spp.,
Dittrichia
Inula
Pulicaria
spp.
others).
Recent
decades
have
brought
a
rapid
development
molecular
analytical
techniques
which
resulted
in
better
understanding
taxonomic
relationships
within
Inuleae
tribe
plethora
data
concerning
constituents
Inuleae-Inulinae.
current
taxonomical
classification
has
introduced
changes
well-established
botanical
names
rearranged
genera
based
on
genetic
studies.
newly
created
together
with
earlier
phytochemical
studies
may
provide
some
complementary
information
biochemical
subtribe.
Moreover,
they
at
least
partly
explain
preparations
traditionally
used
therapy.
review
aimed
systematize
knowledge
polyphenols
Inulae-Inulinae.
