Water-mediated dipole transfer and deoxygenation of nitrones: Experimental and computational mechanistic insights

Journal of Molecular Structure, Год журнала: 2025, Номер unknown, С. 141947 - 141947

Опубликована: Март 1, 2025

Язык: Английский

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Remote Organ Damage Induced by Stroke: Molecular Mechanisms and Comprehensive Interventions

Antioxidants and Redox Signaling, Год журнала: 2025, Номер unknown

Опубликована: Апрель 2, 2025

Significance: Damage after stroke is not only limited to the brain but also often occurs in remote organs, including heart, lung, liver, kidney, digestive tract, and spleen, which are frequently affected by complex pathophysiological changes. The organs human body closely connected, signals transmitted through various molecular substances could regulate changes of organs. Recent Advances: latest studies have shown that inflammatory response plays an important role organ damage stroke, can aggravate activating oxidative stress, sympathetic axis, hypothalamic disturbing immunological homeostasis. Remote cause brain, aggravating damage. Critical Issues: Therefore, in-depth exploration mechanisms adopting corresponding comprehensive intervention strategies become necessary reduce promote protection. Future Directions: strategy involves multifaceted treatment methods such as inflammation regulation, antioxidants, neural stem cell differentiation. It provides a promising alternative for recovery patients inspiration future research treatment. interconnected at level. Only levels we save protect greatest extent. Antioxid. Redox Signal. 00, 000-000.

Язык: Английский

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Synthesis of a Triterpene Analog of α-phenyl-N-tert-butylnitrone

Chemistry of Natural Compounds, Год журнала: 2024, Номер 60(6), С. 1197 - 1199

Опубликована: Ноя. 1, 2024

Язык: Английский

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Synthesis of Nitrones Based on Triterpenes C<sup>3</i>-Hydroxylamines of the Lupane Series

Журнал Общей Химии, Год журнала: 2024, Номер 94(7), С. 805 - 814

Опубликована: Дек. 20, 2024

Язык: Английский

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