Plant-Based Diets and Their Associations with Physical Performance in the Baltimore Longitudinal Study of Aging DOI Open Access
Galya Bigman, Marius Emil Rusu, Amber S. Kleckner

и другие.

Nutrients, Год журнала: 2024, Номер 16(23), С. 4249 - 4249

Опубликована: Дек. 9, 2024

Background: Plant-based diets are associated with various health benefits; however, their impact on physical performance in aging populations remains unclear. Objectives: To investigate the associations between adherence to plant-based and performance, focusing potential protective effects against age-related declines function. Methods: Data were obtained from men women aged 40 years or older Baltimore Longitudinal Study of Aging (BLSA) (mean ± SD age: 68 13 at first dietary visit; n = 1389). Dietary intake was assessed using a food frequency questionnaire (FFQ). diets, calculated 18 groups, categorized as overall (PDI), healthful (hPDI), unhealthful (uPDI), tertiles across visits analyzed. Multivariable linear mixed-effects models used examine association repeated measurements three outcomes—Short Physical Performance Battery (SPPB), grip strength (kg), gait speed (m/s)—and each diet. Results: In fully adjusted models, SPPB significantly both hPDI uPDI, but not PDI. For hPDI, intermediate tertile showed greatest benefit, scores 0.5 points higher (βT2vs.T1 0.50, 95% CI: 0.30–0.70, p < 0.001) over follow-up period. contrast, for 0.27-point lower score seen (βT3vs.T1 −0.27, −0.48 −0.07, 0.009). Longitudinally, positively 1.14, 0.24–2.05, 0.0013). Similar results observed adults ≥65 years. Conclusions: Adherence may benefit body function muscle strength, while uPDI appears have adverse effects. This suggests that quality foods is essential maintaining functional well-being adults. Further research needed confirm these findings, explore underlying mechanisms, identify strategies optimize patterns populations.

Язык: Английский

Dietary flaxseed: Cardiometabolic benefits and its role in promoting healthy aging DOI Creative Commons
Setor K. Kunutsor, Davinder S. Jassal,

Amir Ravandi

и другие.

GeroScience, Год журнала: 2025, Номер unknown

Опубликована: Янв. 16, 2025

Flaxseed, a rich source of omega-3 polyunsaturated fatty acid alpha-linolenic (ALA), lignans, and soluble fiber, has attracted attention for its potential to improve multiple cardiometabolic risk factors. While benefits are well-recognized, comprehensive evaluations direct impact on clinical outcomes, such as the prevention or progression diseases, remain limited. Additionally, support healthy aging longevity through fundamental biological mechanisms not been fully elucidated. This review synthesizes existing research flaxseed supplementation, highlighting effects factors underlying mechanisms, broader implications health promotion aging. Findings demonstrate that supplementation significantly improves several factors, including body weight, mass index, lipid levels, blood pressure, glycemic measures, markers inflammation (e.g., C-reactive protein interleukin-6), oxidative stress, liver enzymes. Blood pressure reductions range from approximately 2 15 mmHg systolic 1 7 diastolic with magnitude influenced by dose, duration, baseline profiles. evidence linking hypertension, metabolic syndrome, dysfunction-associated steatotic disease, type diabetes, chronic kidney cardiovascular disease is limited, bioactive components-ALA, fiber-are strongly associated reduced risks these conditions. The mediated pathways, anti-inflammatory antioxidant effects, improved glucose metabolism insulin sensitivity, modulation gut microbiota, enhanced vascular health. Beyond may influence key processes relevant aging, underscoring promote longevity. Optimal appear be achieved ground whole at doses ≥ 30 g/day least 12 weeks, particularly among individuals high risk. Future should focus elucidating flaxseed's action, clarifying role in prevention, refining dietary recommendations harness interventions.

Язык: Английский

Процитировано

1
MNT Evidence Update: Comparative Effectiveness of Dietary Programs for Reducing Mortality and Cardiovascular Events in Adults with Increased Cardiovascular Risk DOI Creative Commons
Zahra Esmaeilinezhad, Gabriel Torbahn, Bradley C. Johnston

и другие.

Advances in Nutrition, Год журнала: 2025, Номер unknown, С. 100399 - 100399

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0
Natural Products from the Mediterranean Area as Wound Healing Agents—In Vitro Studies: A Systematic Review DOI Creative Commons

Eleftheria Chorti-Tripsa,

Vasilios Galanis,

Theodoros C. Constantinidis

и другие.

Antioxidants, Год журнала: 2025, Номер 14(4), С. 484 - 484

Опубликована: Апрель 17, 2025

Wound healing is a process that happens when lost tissue replenishes. For this process, both protective elements and wound accelerating factors are required. In recent years, the search for natural products promote faster prevent adverse effects has gained momentum. This systematic review, adhering to PRISMA (Preferred Reporting Items Systematic reviews Meta-Analyses) criteria, of products, with focus on from Mediterranean region. study sourced PubMed Scopus databases eligible articles publications over last six years. Due information volume, only in vitro studies were included review. The criteria set concluded 28 included. These showed many found have been studied treatment wounds. effect seems be related dose, type wounded tissue, application time. Moreover, half additionally tested shown antioxidant activity through DPPH (2,2-diphenyl-1-picrylhydrazyl), ABTS (2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), FRAP (Ferric Reducing Antioxidant Power) assays.

Язык: Английский

Процитировано

0
Fructose-mediated AGE-RAGE axis: approaches for mild modulation DOI Creative Commons
Halyna Semchyshyn

Frontiers in Nutrition, Год журнала: 2024, Номер 11

Опубликована: Дек. 4, 2024

Fructose is a valuable and healthy nutrient when consumed at normal levels (≤50 g/day). However, long-term consumption of excessive fructose elevated endogenous production can have detrimental health impacts. Fructose-initiated nonenzymatic glycation (fructation) considered as one the most likely mechanisms leading to generation reactive species propagation processes. In later stages glycation, poorly degraded advanced products (AGEs) are irreversibly produced accumulated in organism an age- disease-dependent manner. Fructose, along with various products-especially AGEs-are present relatively high concentrations our daily diet. Both exogenous AGEs exhibit wide range biological effects, which be associated following: (1) efficient sources

Язык: Английский

Процитировано

0
Plant-Based Diets and Their Associations with Physical Performance in the Baltimore Longitudinal Study of Aging DOI Open Access
Galya Bigman, Marius Emil Rusu, Amber S. Kleckner

и другие.

Nutrients, Год журнала: 2024, Номер 16(23), С. 4249 - 4249

Опубликована: Дек. 9, 2024

Background: Plant-based diets are associated with various health benefits; however, their impact on physical performance in aging populations remains unclear. Objectives: To investigate the associations between adherence to plant-based and performance, focusing potential protective effects against age-related declines function. Methods: Data were obtained from men women aged 40 years or older Baltimore Longitudinal Study of Aging (BLSA) (mean ± SD age: 68 13 at first dietary visit; n = 1389). Dietary intake was assessed using a food frequency questionnaire (FFQ). diets, calculated 18 groups, categorized as overall (PDI), healthful (hPDI), unhealthful (uPDI), tertiles across visits analyzed. Multivariable linear mixed-effects models used examine association repeated measurements three outcomes—Short Physical Performance Battery (SPPB), grip strength (kg), gait speed (m/s)—and each diet. Results: In fully adjusted models, SPPB significantly both hPDI uPDI, but not PDI. For hPDI, intermediate tertile showed greatest benefit, scores 0.5 points higher (βT2vs.T1 0.50, 95% CI: 0.30–0.70, p < 0.001) over follow-up period. contrast, for 0.27-point lower score seen (βT3vs.T1 −0.27, −0.48 −0.07, 0.009). Longitudinally, positively 1.14, 0.24–2.05, 0.0013). Similar results observed adults ≥65 years. Conclusions: Adherence may benefit body function muscle strength, while uPDI appears have adverse effects. This suggests that quality foods is essential maintaining functional well-being adults. Further research needed confirm these findings, explore underlying mechanisms, identify strategies optimize patterns populations.

Язык: Английский

Процитировано

0