SSRN Electronic Journal,
Год журнала:
2022,
Номер
unknown
Опубликована: Янв. 1, 2022
By
using
the
microscopic
Beer-Lambert
law
(MBL),
we
propose
a
fast
and
effective
analysis
method
for
retrieving
absorption
coefficient
changes
of
sample
from
broadband
frequency-domain
diffuse
optical
spectroscopy
(FD-DOS)
or
near-infrared
(FD-NIRS)
data.
To
verify
advantages
our
proposed
method,
built
single-distance
imaging
(DOI)
system
measuring
amplitude
phase
transmitted
light.
Fifteen
liquid
phantoms
with
different
scattering
coefficients
are
prepared,
in
[[EQUATION]]
retrieved
by
conventional
nonlinear
least-squares
fitting
(NLSF)
MBL
methods.
Results
show
that
computation
time
precision
50
times
six
better
than
those
NLSF
respectively.
Biosensors,
Год журнала:
2021,
Номер
11(10), С. 389 - 389
Опубликована: Окт. 13, 2021
Functional
Near-Infrared
Spectroscopy
(fNIRS)
is
a
wearable
optical
spectroscopy
system
originally
developed
for
continuous
and
non-invasive
monitoring
of
brain
function
by
measuring
blood
oxygen
concentration.
Recent
advancements
in
brain-computer
interfacing
allow
us
to
control
the
neuron
combining
it
with
fNIRS
regulate
cognitive
function.
In
this
review
manuscript,
we
provide
information
regarding
current
advancement
how
provides
advantages
developing
enable
We
also
briefly
discuss
about
can
use
technology
further
applications.
Functional
near-infrared
spectroscopy
(fNIRS)
is
an
optical
imaging
technique
for
assessing
human
brain
activity
by
noninvasively
measuring
the
fluctuation
of
cerebral
oxygenated-
and
deoxygenated-hemoglobin
concentrations
associated
with
neuronal
activity.
Owing
to
its
superior
mobility,
low
cost,
good
tolerance
motion,
past
few
decades
have
witnessed
a
rapid
increase
in
research
clinical
use
fNIRS
variety
psychiatric
disorders.
In
this
perspective
article,
we
first
briefly
summarize
state-of-the-art
concerning
psychiatry.
particular,
highlight
diverse
applications
research,
advanced
development
instruments,
novel
study
designs
exploring
We
then
discuss
some
open
challenges
share
our
perspectives
on
future
practice.
conclude
that
holds
promise
becoming
useful
tool
settings
respect
developing
closed-loop
systems
improving
individualized
treatments
diagnostics.
Biomedical Optics Express,
Год журнала:
2023,
Номер
14(7), С. 3506 - 3506
Опубликована: Май 30, 2023
Near-infrared
spectroscopy
(NIRS)
is
an
established
technique
for
measuring
tissue
oxygen
saturation
(StO2),
which
of
high
clinical
value.
For
tissues
that
have
layered
structures,
it
challenging
but
clinically
relevant
to
obtain
StO2
the
different
layers,
e.g.
brain
and
scalp.
this
aim,
we
present
a
new
method
data
analysis
time-domain
NIRS
(TD-NIRS)
two-layered
blood-lipid
phantom.
The
enables
accurate
determination
even
large
changes
absorption
coefficient
(Δµa)
in
multiple
layers.
By
adding
Δµa
baseline
µa,
provides
absolute
µa
hence
utilizes
(i)
statistical
moments
distributions
times
flight
photons
(DTOFs),
(ii)
analytical
solution
diffusion
equation
N-layered
medium,
(iii)
Levenberg-Marquardt
algorithm
(LMA)
determine
layers
from
moments.
suitable
oximetry
(relying
on
µa)
as
well
functional
(fNIRS)
applications
Δµa).
Experiments
were
conducted
phantom,
enabled
us
simulate
dynamic
two
first
time.
Two
separate
compartments,
mimic
superficial
deep
hold
mixtures
can
be
deoxygenated
(using
yeast)
oxygenated
(by
bubbling
oxygen)
independently.
Simultaneous
measurements
performed
medium
(variable
layer
thickness,
L),
(homogeneous),
and/or
(homogeneous).
In
experiments
involving
ink,
increased
nominal
one
compartments
0.05
0.25
cm-1,
L
set
14.5
mm.
three
blood
(L
12,
15,
or
17
mm),
used
protocol
consisting
six
deoxygenation
cycles.
A
state-of-the-art
multi-wavelength
TD-NIRS
system
measured
simultaneously
compartment
reference.
accurately
determined
(and
StO2)
both
compartments.
significant
progress
overcoming
contamination
layer,
beneficial
fNIRS
applications,
may
improve
head.
advanced
phantom
assist
ongoing
effort
towards
more
realistic
standardized
performance
tests
oximetry.
Data
MATLAB
codes
study
made
publicly
available.
Instruments,
Год журнала:
2024,
Номер
8(1), С. 24 - 24
Опубликована: Март 17, 2024
In
this
study,
a
novel
system
was
designed
to
enhance
the
efficiency
of
data
acquisition
in
portable
and
compact
instrument
dedicated
spectral
analysis
various
surfaces,
including
plant
leaves,
materials
requiring
characterization
within
410
915
nm
range.
The
proposed
incorporates
two
nine-band
detectors
positioned
on
top
bottom
target
surface,
each
equipped
with
digitally
controllable
LED.
are
capable
measuring
both
reflection
transmission
properties,
depending
LED
configuration.
Specifically,
when
upper
is
activated,
lower
detector
operates
without
its
LED,
enabling
precise
measurement
light
transmitted
through
sample.
process
reversed
subsequent
iterations,
facilitating
an
accurate
assessment
for
side
surface.
For
reliability,
error
estimation
utilizes
color
checker,
followed
by
multi-layer
perceptron
(MLP)
implementation
integrated
into
microcontroller
unit
(MCU)
using
TinyML
technology
real-time
refined
acquisition.
constructed
3D-printed
components
cost-effective
electronics.
It
also
supports
USB
or
Bluetooth
communication
transmission.
This
innovative
marks
significant
advancement
analysis,
particularly
research,
offering
potential
disease
detection
nutritional
deficiency
assessment.
Biomedical Optics Express,
Год журнала:
2021,
Номер
12(10), С. 6629 - 6629
Опубликована: Сен. 9, 2021
We
present
and
validate
a
multi-wavelength
time-domain
near-infrared
spectroscopy
(TD-NIRS)
system
that
avoids
switching
wavelengths
instead
exploits
the
full
capability
of
supercontinuum
light
source
by
emitting
acquiring
signals
for
whole
chosen
range
wavelengths.
The
was
designed
muscle
brain
oxygenation
monitoring
in
clinical
environment.
A
pulsed
laser
emits
broadband
each
two
detection
modules
acquires
distributions
times
flight
photons
(DTOFs)
16
spectral
channels
(used
width
12.5
nm
/
channel),
providing
total
32
DTOFs
at
up
to
3
Hz.
Two
fibers
fiber
bundles
allow
simultaneous
measurements
positions
on
tissue
or
source-detector
separations.
Three
established
protocols
(BIP,
MEDPHOT,
nEUROPt)
were
used
quantitatively
assess
system's
performance,
including
linearity,
coupling,
accuracy,
depth
sensitivity.
Measurements
performed
homogeneous
phantoms
inhomogeneous
(solid
liquid).
Furthermore,
blood-lipid
with
varied
amount
blood
Intralipid
provide
strongest
validation
accurate
oximetry.
retrieved
hemoglobin
concentrations
oxygen
saturation
match
well
reference
values
obtained
using
commercially
available
NIRS
(OxiplexTS)
gas
analyzer
(ABL90
FLEX),
except
discrepancy
occurs
lowest
Intralipid.
In-vivo
forearm
three
healthy
volunteers
during
arterial
(250
mmHg)
venous
(60
cuff
occlusions
an
example
expected
hemodynamic
changes
follow
previously
well-described
physiologies.
All
results,
quantitative
parameters,
can
be
compared
other
systems
report
similar
tests.
Overall,
presented
TD-NIRS
has
exemplary
performance
evaluated
state-of-the-art
assessment
methods.
IEEE photonics journal,
Год журнала:
2021,
Номер
13(3), С. 1 - 9
Опубликована: Май 14, 2021
Non-invasive
glucose
monitoring
sensors
are
promising
techniques
in
diabetes
management.
In
particular,
optical-based
near-infrared
label-free,
compact,
user-friendly,
and
inexpensive.
They
require
no
daily
calibration
can
provide
continuous
level
monitoring.
However,
these
still
the
development
stage
since
their
accuracy
is
not
widely
accepted
by
medical
professionals.
Here,
we
introduce
an
optimized
dual-channel
approach
for
this
kind
of
sensor
where
four
optodes
short
long
channels
employed.
The
channel
signal
that
contains
useful
information
about
be
utilized
to
calculate
contents
dermis
layer
skin
while
measure
interference
"noise"
originating
from
epidermis
layer.
So,
latter
then
removed
signal.
This
work
investigates
optimal
source-detector
separation
(SDS)
both
a
wide
range
wavelengths
1200
nm
1900
nm.
Based
on
sensitivity
distributions
layers
signal-to-noise
ratio,
it
suggested
2
mm
SDS
distance
with
wavelength
1450
potential
choice
channel.
Moreover,
6
at
1750
may
pave
way
further
optimization
non-invasive
will
adopted
healthcare
sector.
IEEE Transactions on Neural Systems and Rehabilitation Engineering,
Год журнала:
2023,
Номер
31, С. 2535 - 2544
Опубликована: Янв. 1, 2023
Wearable
functional
near-infrared
spectroscopy
(fNIRS)
for
measuring
brain
function,
in
terms
of
hemodynamic
responses,
is
pervading
our
everyday
life
and
holds
the
potential
to
reliably
classify
cognitive
load
a
naturalistic
environment.
However,
human's
response,
behavior,
task
performance
vary,
even
within
across
homogeneous
individuals
(with
same
training
skill
sets),
which
limits
reliability
any
predictive
model
human.
In
context
high-stakes
tasks,
such
as
military
first-responder
operations,
real-time
monitoring
functions
relating
it
ongoing
task,
outcomes,
behavioral
dynamics
personnel
teams
invaluable.
this
work,
portable
wearable
fNIRS
system
(WearLight)
developed
by
author
was
upgraded,
an
experimental
protocol
designed
image
prefrontal
cortex
(PFC)
area
25
healthy
participants
environment
while
performed
n-back
working
memory
(WM)
tasks
with
four
difficulty
levels.
The
raw
signals
were
processed
using
signal
processing
pipeline
derive
brain's
responses.
An
unsupervised
k-means
machine
learning
(ML)
clustering
approach,
utilizing
task-induced
responses
input
variables,
suggested
three
unique
participant
groups.
Task
%
correct,
missing,
reaction
time,
inverse
efficiency
score
(IES),
proposed
IES
extensively
evaluated
each
Results
showed
that,
on
average,
response
increased,
whereas
degraded,
increasing
WM
load.
regression
correlation
analysis
performance,
(TPH)
revealed
interesting
hidden
characteristics
variation
TPH
relationship
between
also
served
better
scoring
method
that
had
distinct
ranges
different
levels
opposed
overlapping
scores
traditional
method.
has
find
groups
manner
study
underlying
Using
presented
paper,
soldiers,
preferentially
forming
small
units
accomplish
based
insights
goals
may
be
helpful.
results
WearLight
can
PFC,
suggests
future
directions
multi-modal
body
sensor
network
(BSN)
combining
advanced
ML
algorithms
state
classification,
physical
prediction,
mitigation
degradation
Diagnostics,
Год журнала:
2023,
Номер
13(2), С. 309 - 309
Опубликована: Янв. 13, 2023
Near-infrared
technology
is
an
emerging
non-invasive
technique
utilized
for
various
medical
applications.
Recently,
there
have
been
many
attempts
to
utilize
NIR
the
continues
monitoring
of
blood
glucose
levels
through
skin.
Different
approaches
and
designs
proposed
measurements.
Light
photons
penetrating
skin
can
undergo
multiple
scattering
events,
actual
optical
pathlength
becomes
larger
than
source-to-detector
separation
(optode
spacing)
in
reflection-mode
configuration.
Thus,
differential
factor
(DPF)
must
be
incorporated
into
modified
Beer-Lambert
law.
The
accurate
estimation
DPF
values
will
lead
quantification
physiological
variations
within
tissue.
In
this
work,
aim
was
systematically
estimate
human
a
range
separations
wavelengths.
Monte
Carlo
(MC)
method
mimic
different
layers
with
properties
water
volume
fractions.
This
work
could
help
improve
accuracy
near-infrared
measurement
Electronics,
Год журнала:
2021,
Номер
10(14), С. 1642 - 1642
Опубликована: Июль 10, 2021
In
this
review,
the
roles
of
detectors
in
various
medical
imaging
techniques
were
described.
Ultrasound,
optical
(near-infrared
spectroscopy
and
coherence
tomography)
thermal
imaging,
magnetic
resonance
computed
tomography,
single-photon
emission
positron
tomography
modalities
considered.
For
each
methodology,
state
art
mainly
used
systems
was
described,
emphasizing
new
technologies
applied.