ACS Applied Polymer Materials, Год журнала: 2025, Номер unknown
Опубликована: Фев. 19, 2025
Язык: Английский
BMEMat, Год журнала: 2024, Номер unknown
Опубликована: Май 24, 2024
Abstract With high biocompatibility and degradability, polysaccharide‐based hydrogels are favorable healthcare materials. However, in many biomedical applications, these materials inconvenient to handle with fixed morphology, unable closely match the wounds, easy detach due insufficient adhesion. Inspired by superior wet adhesive properties of marine mussels, researchers have used mussel‐inspired chemistry create mussel‐mimetic injectable that simple operate, controllable shape, highly adhesive, significantly extended their applications such as tissue adhesives, delivery vehicles, engineering scaffolds, wearable sensors. there few comprehensive reviews on both adhesion injectability, critical analyses hydrogels' preparation methods applications. This review fills this gap systematically summarizes strategies for novel hydrogels, including modifying polysaccharides catechol‐ or pyrogallol‐containing small molecules leveraging different interactions between catechol‐/pyrogallol‐modified other substances form crosslinked hydrogels. Furthermore, recent discussed, future challenges research trends proposed.
Язык: Английский
Процитировано
8
ACS Applied Bio Materials, Год журнала: 2024, Номер 7(7), С. 4231 - 4253
Опубликована: Июнь 10, 2024
Electrospun polymeric nanofibers are essential in various fields for applications because of their unique properties. Their features similar to extracellular matrices, which suggests them healthcare fields, such as antimicrobials, tissue engineering, drug delivery, wound healing, bone regeneration, and biosensors. This review focuses on the synthesis electrospun nanofibers, surface modification, biomedical applications. Nanofibers can be fabricated from both natural synthetic polymers composites. Even though they mimic (physicochemical characteristics) not always capable fulfilling purpose target application. Therefore, need improved via modification techniques. Both needle-based needleless electrospinning thoroughly discussed. Various techniques setups employed each method also reviewed. Furthermore, pre- postspinning approaches including instrument design targeted applications, extensively In this way, remarkable potential highlighted reveal future research directions dynamic field.
Язык: Английский
Процитировано
8
Regenerative Engineering and Translational Medicine, Год журнала: 2025, Номер unknown
Опубликована: Янв. 13, 2025
Язык: Английский
Процитировано
1
Acta Biomaterialia, Год журнала: 2023, Номер 170, С. 185 - 201
Опубликована: Авг. 26, 2023
Язык: Английский
Процитировано
21
Materials, Год журнала: 2023, Номер 16(12), С. 4425 - 4425
Опубликована: Июнь 16, 2023
This paper presents a systematic review of key sector the much promising and rapidly evolving field biomedical engineering, specifically on fabrication three-dimensional open, porous collagen-based medical devices, using prominent freeze-drying process. Collagen its derivatives are most popular biopolymers in this field, as they constitute main components extracellular matrix, therefore exhibit desirable properties, such biocompatibility biodegradability, for vivo applications. For reason, freeze-dried sponges with wide variety attributes can be produced have already led to range successful commercial chiefly dental, orthopedic, hemostatic, neuronal However, collagen display some vulnerabilities other low mechanical strength poor control their internal architecture, many studies focus settlement these defects, either by tampering steps process or combining additives. Furthermore, freeze drying is still considered high-cost time-consuming that often used non-optimized manner. By applying an interdisciplinary approach advances technological fields, statistical analysis, implementing Design Experiments, Artificial Intelligence, opportunity arises further evolve sustainable strategic manner, optimize resulting products well create new opportunities field.
Язык: Английский
Процитировано
20
International Journal of Biological Macromolecules, Год журнала: 2023, Номер 255, С. 128121 - 128121
Опубликована: Ноя. 19, 2023
Язык: Английский
Процитировано
18
The minerals, metals & materials series, Год журнала: 2024, Номер unknown, С. 469 - 483
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
7
Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials, Год журнала: 2024, Номер 157, С. 106661 - 106661
Опубликована: Июль 14, 2024
Язык: Английский
Процитировано
7
Biomimetics, Год журнала: 2024, Номер 9(9), С. 511 - 511
Опубликована: Авг. 24, 2024
Calcium-based materials, such as calcium carbonate, phosphate, and silicate, have attracted significant attention in biomedical research, owing to their unique physicochemical properties versatile applications. The distinctive characteristics of these including inherent biocompatibility tunable structures, hold promise for applications bone regeneration tissue engineering. This review explores the calcium-containing particularly regeneration. Their remarkable biocompatibility, nanostructures, multifaceted functionalities make them pivotal advancing regenerative medicine, drug delivery system, biomimetic scaffold evolving landscape research continues uncover new possibilities, positioning calcium-based materials key contributors next generation innovative biomaterial scaffolds.
Язык: Английский
Процитировано
6
Journal of Clinical Medicine, Год журнала: 2023, Номер 12(22), С. 6962 - 6962
Опубликована: Ноя. 7, 2023
Guided bone regeneration (GBR) is a promising technique in tissue engineering that aims to replace lost or injured using resorbable scaffolds. The promotion of osteoblast adhesion, migration, and proliferation greatly aided by GBR materials, surface changes are critical imitating the natural structure improve cellular responses. Moreover, interactions between bioresponsive scaffolds, growth factors (GFs), immune cells, stromal progenitor cells essential promoting regeneration. This literature review comprehensively discusses various aspects scaffolds engineering, encompassing scaffold design, fabrication techniques, advanced manufacturing methods, including three-dimensional printing. In addition, this explores modifications replicate native structures their impact on mechanisms described, providing information how GFs, orchestrate healing. Practical applications clinical settings presented underscore importance these principles integration, healing, Furthermore, delves into emerging areas metamaterials artificial intelligence regenerative medicine. These interdisciplinary approaches hold immense promise for furthering improving therapeutic outcomes, leading enhanced patient well-being. potential combining material science, manufacturing, biology showcased as pathway advance addressing variety needs challenges. By comprehensive narrative, detailed, up-to-date account scaffolds' role transformative offered.
Язык: Английский
Процитировано
13