Ophthalmic Formulations for the Treatment of Allergic Conjunctivitis and Their Effect on the Ocular Surface: A Review of Safety and Tolerability Assessments in Clinical Trials

Journal of Clinical Medicine, Год журнала: 2024, Номер 13(22), С. 6903 - 6903

Опубликована: Ноя. 16, 2024

Allergic conjunctivitis (AC) is the most common allergic eye disorder. Antiallergic eyedrops are first line of pharmacological treatment. However, application antiallergic can potentially alter tear homeostasis and affect ocular surface, which may result in iatrogenic diseases such as dye disease (DED). Long-term treatment AC with containing preservatives other components increase risk DED surface damage. Here, we examined 20 clinical trials published during past ten years antihistamine ophthalmic formulations AC, to evaluate extent evidence about their safety tolerability. Remarkably, find that lack an evaluation critical parameters, film break-up time, volume, corneal conjunctival damage, inflammation, properly assess state after prolonged There a need awareness use specific do not DED.

Язык: Английский

Meeting Challenges in the Diagnosis and Treatment of Glaucoma

Bioengineering, Год журнала: 2024, Номер 12(1), С. 6 - 6

Опубликована: Дек. 25, 2024

Glaucoma, a progressive and multifactorial optic neurodegenerative disease, still poses significant challenges in both diagnosis management remains perpetual enigma [...].

Язык: Английский