Angiotensin Converting Enzyme 2 (ACE2) - A macromolecule and its impact on human reproduction during COVID-19 pandemic DOI Open Access

G. Gulothungan,

A. S. Vickram,

Kuldeep Dhama

и другие.

Journal of Experimental Biology and Agricultural Sciences, Год журнала: 2022, Номер 10(5), С. 960 - 977

Опубликована: Окт. 31, 2022

Coronavirus disease 2019 (COVID 19) is caused by severe acute respiratory syndrome novel coronavirus 2 (SARS-nCoV-2). It has been declared a pandemic the World Health Organization (WHO) on March 11, 2020. Since then, several researchers have worked/ are working this virus multifactorial approach to finding out mechanism of entry, transmission route, post-infection replication process, survival, and post-recovery utilities. As we know, SARS, MERS, Zika viruses affected human reproductive potentials, consequently, COVID 19 also can affect both men's women's potential through ACE2 macromolecule. This study aimed summarize role ACE2- macromolecule in entry further processes path men women. Research articles were searched NCBI-NLM, Google Scholar, Scopus databases. We based phrase “COVID 19”, “ACE2”, “ACE2 testes”, female tract”, during pregnancy”, early embryo”, impact reproduction” selected for summarizing article. Most recent our understanding. The results revealed that impacts Testes most vulnerable organ prone infection men, vaginal fluid uterus could be choice female. Till now, not directly detected semen samples fluid. Results concluded plays major infection, expression more testes, ovary, uterus, vagina. reproduction lead loss fertility status while. All antiviral treatments pose negative reproduction. Further research should carried already existing theoretical hypothesis SARS-Co-V-2

Язык: Английский

Fertility dynamics through historical pandemics and COVID-19 in Switzerland, 1871–2022 DOI Creative Commons
Katarina L. Matthes, Mathilde Le Vu, Kaspar Staub

и другие.

Population Studies, Год журнала: 2025, Номер unknown, С. 1 - 16

Опубликована: Март 11, 2025

We follow general fertility rates (GFRs) in Switzerland up to 2022, with a focus on their dynamics during and after pandemics. Historical influenza pandemics (1889–90, 1918–20, 1957) have consistently led temporary declines births between six nine months the pandemic peak. High of miscarriage may explain these findings. After 1889–90 1918–20 pandemics, short-term baby booms occurred. For recent Covid-19 pandemic, appear more complex. The GFR had already been declining since 2018, before hit Switzerland. During shortly first two waves 2020, there was an increase conceptions, leading higher 2021: shutdown measures brought planned pregnancies forwards. Subsequently, declined from February 2022; one possible explanation is that were intentionally postponed until vaccination. Following population-level observations, in-depth studies are needed understand better why affected by

Язык: Английский

Процитировано

0

Clinical Spectrum of Long COVID: Effects on Female Reproductive Health DOI Creative Commons

Syeda Maham,

Mee‐Sup Yoon

Viruses, Год журнала: 2024, Номер 16(7), С. 1142 - 1142

Опубликована: Июль 16, 2024

The COVID-19 pandemic caused by SARS-CoV-2 has presented numerous health challenges, including long-term COVID, which affects female reproductive health. This review consolidates the current research on impact of menstrual cycle, ovarian function, fertility, and overall gynecological study emphasizes role angiotensin-converting enzyme receptors in viral entry subsequent tissue-specific pathological effects. It also explores potential influence long COVID hormonal balance immune responses, contributing to irregularities impaired function. findings indicate a higher prevalence among women, highlighting substantial implications for need sex-sensitive longitudinal studies. Enhanced surveillance targeted are essential develop effective interventions that prioritize women's well-being following infection. advocates sex-informed approach ongoing healthcare strategies, aiming provide up-to-date pertinent data providers general public, ultimately improving outcomes females affected COVID.

Язык: Английский

Процитировано

4

Integrative Assessment of Seminal Plasma Biomarkers: A Narrative Review Bridging the Gap between Infertility Research and Clinical Practice DOI Open Access
Efthalia Moustakli, Athanasios Zikopoulos, Charikleia Skentou

и другие.

Journal of Clinical Medicine, Год журнала: 2024, Номер 13(11), С. 3147 - 3147

Опубликована: Май 27, 2024

Infertility represents a significant global health challenge impacting millions of couples worldwide. Approximately half all infertile exhibit compromised semen quality, indicative diminished male fertility. While the diagnosis infertility traditionally relies on analysis, its limitations in providing comprehensive assessment reproductive have spurred efforts to identify novel biomarkers. Seminal plasma, complex fluid containing proteins, lipids, and metabolites, has emerged as rich source such indicators. Reproduction depends heavily seminal primary transporter chemicals from glands. It provides non-invasive sample for urogenital diagnostics demonstrated potential identification biomarkers linked illnesses system. The abundance proteins enabled deeper understanding their biological functions, origins, differential expression various conditions associated with infertility, including azoospermia, asthenozoospermia, oligozoospermia, teratozoospermia, among others. true prevalence is understated due current diagnostic techniques. This review critically evaluates landscape plasma utility assessing infertility. Βy bridging gap between research clinical practice, integrative offers multimodal approach comprehensively evaluate

Язык: Английский

Процитировано

3

COVID-19 and Ehlers-Danlos Syndrome: The Dangers of the Spike Protein of SARS-CoV-2 DOI
Jean‐Marc Sabatier, Ziad Fajloun, Christian Legros

и другие.

Infectious Disorders - Drug Targets, Год журнала: 2023, Номер 23(3)

Опубликована: Янв. 5, 2023

Язык: Английский

Процитировано

8

Why do Athletes Develop Very Severe or Fatal Forms of COVID after Intense Exercise Following SARS-CoV-2 Infection or Anti-COVID Vaccination? DOI
Ziad Fajloun, Ziad Abi Khattar, Hervé Kovacic

и другие.

Infectious Disorders - Drug Targets, Год журнала: 2023, Номер 23(4)

Опубликована: Янв. 12, 2023

Язык: Английский

Процитировано

8

SIBO: The Trail of a "New" Human Pathology Associated with Multiple Severe and Disabling COVID-19 and Long COVID Symptoms or Induced by the Anti-COVID-19 Vaccine DOI
Ziad Fajloun, Ziad Abi Khattar, Hervé Kovacic

и другие.

Infectious Disorders - Drug Targets, Год журнала: 2023, Номер 23(4)

Опубликована: Фев. 10, 2023

Язык: Английский

Процитировано

6

Anti-COVID-19 Vaccination, COVID-19, and Female Contraception: The Exacerbated Risks (Thromboembolism) of the Estrogen-progestin Pill DOI
Ziad Fajloun, Ziad Abi Khattar, Hervé Kovacic

и другие.

Infectious Disorders - Drug Targets, Год журнала: 2023, Номер 23(4)

Опубликована: Фев. 24, 2023

Язык: Английский

Процитировано

6

Understanding and Relieving of Neuropathic Disorders in the Long COVID DOI
Ziad Fajloun, Ziad Abi Khattar, Hervé Kovacic

и другие.

Infectious Disorders - Drug Targets, Год журнала: 2023, Номер 23(4)

Опубликована: Фев. 27, 2023

Язык: Английский

Процитировано

5

COVID-19 and Parkinson's Disease: The Link also Established! DOI
Ziad Fajloun, Yingliang Wu, Zhijian Cao

и другие.

Infectious Disorders - Drug Targets, Год журнала: 2023, Номер 23(8)

Опубликована: Июнь 21, 2023

Язык: Английский

Процитировано

3

The Unsuspected Role of the Renin-Angiotensin System (RAS): Could its Dysregulation be at the Root of All Non-Genetic Human Diseases? DOI
Ziad Fajloun, Jean‐Marc Sabatier

Infectious Disorders - Drug Targets, Год журнала: 2023, Номер 24(1)

Опубликована: Сен. 14, 2023

Язык: Английский

Процитировано

3