Опубликована: Июнь 7, 2024
Язык: Английский
Sensors, Год журнала: 2024, Номер 24(10), С. 3152 - 3152
Опубликована: Май 15, 2024
Providing employees with proper work conditions should be one of the main concerns any employer. Even so, in many cases, shifts chronically expose workers to a wide range potentially harmful compounds, such as ammonia. Ammonia has been present composition products commonly used industries, namely production lines, and also laboratories, schools, hospitals, others. Chronic exposure ammonia can yield several diseases, irritation pruritus, well inflammation ocular, cutaneous, respiratory tissues. In more extreme is related dyspnea, progressive cyanosis, pulmonary edema. As such, use needs properly regulated monitored ensure safer environments. The Occupational Safety Health Administration European Agency for at Work have already commissioned regulations on acceptable limits Nevertheless, monitoring gas still not normalized because appropriate sensors difficult find commercially available products. To help promote promising methods developing sensors, this will compile compare results published so far.
Язык: Английский
Процитировано
5
Elsevier eBooks, Год журнала: 2025, Номер unknown, С. 313 - 327
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Biosensors, Год журнала: 2025, Номер 15(2), С. 88 - 88
Опубликована: Фев. 5, 2025
Surface acoustic wave (SAW) sensor technology is a promising approach to diagnosing cancer through the detection of biomarkers due its high sensitivity, potential label-free operation, and fast response times, and, fundamentally, because it non-invasive technique in comparison with current traditional diagnostic techniques for cancer. This review focuses on this application, purpose, recent literature detected by advanced has been compiled, including that volatile organic compounds (VOCs) from exhaled breath larger biomolecules such as proteins, DNA, microRNAs body fluids, which demonstrates great versatility. The conventional biomarker biofluids, ELISA, PCR, SPR, UV absorbance, exhibit limitations costs, slow reduced need specialized instrumentation, requirement highly trained personnel. Different SAW configurations are discussed attention paid their specific properties, propagation modes, suitability different environments. Detailed studies reviewed, highlighting lung, colorectal, prostate, breast, ovarian diagnostics, well circulating tumor cells cancerous cell growth. identifies challenges, optimizing addressing environmental interferences, clinical validation. Finally, future research directions proposed, emphasizing use VOC integration into hybrid systems microfluidic platforms enable creation scalable, tools early stages, way, minimize morbidity mortality associated disease.
Язык: Английский
Процитировано
0
ACS Sensors, Год журнала: 2025, Номер unknown
Опубликована: Март 10, 2025
Wearable gas sensors offer remarkable advantages in terms of portability and real-time monitoring, rendering them highly promising for various applications such as environmental detection, health early disease diagnosis. However, the most widely used oxide semiconductor encounter substantial challenges achieving mechanical flexibility room-temperature detection due to their inherent rigidity, brittleness, reliance on high operating temperatures. Herein, an all-inorganic wearable sensor is fabricated by depositing anatase/rutile TiO2 (TiO2-A/R) homojunction a flexible yttria-stabilized zirconia (YSZ) nanofiber substrate using atomic layer deposition technology. The combination YSZ ultrathin sensing (∼13 nm) endows with tiny linear strains (0.55%) when subjected radius curvature 25 μm. As result, inorganic YSZ/TiO2-A/R can be folded multiple times without fracturing maintain stable electrical connectivity during cyclic bending. Furthermore, utilization photoactive homojunctions allows activated UV light operated at room temperature. efficient separation efficiency photogenerated carriers, which stems from interfacial electric field homojunctions, significantly enhances sensor's response, leading low limit 0.15 ppm acetone. In addition, was anchored mask successfully utilized simulated breathing diabetics; response signals demonstrate its potential noninvasive diabetes This study provides valuable reference advancement sensors, offering insights into
Язык: Английский
Процитировано
0
Journal of Condensed Matter, Год журнала: 2025, Номер 3(01), С. 56 - 63
Опубликована: Март 25, 2025
Timely cancer detection is crucial for improved survival rates and enhanced treatment efficacy. Volatile organic compounds (VOCs) have attracted much attention as potential biomarkers diagnosis because of their distinctive patterns linked to metabolic abnormalities in cells. This review aims examine advanced biosensor technologies that utilize VOCs early detection. research seeks elucidate the transformative VOC biosensors therapy by analyzing existing advancements, significant challenges, anticipated advancement domain.
Язык: Английский
Процитировано
0
Microchemical Journal, Год журнала: 2025, Номер unknown, С. 113700 - 113700
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0
Clinical and Experimental Medicine, Год журнала: 2024, Номер 25(1)
Опубликована: Дек. 21, 2024
This review paper explores the realm of non-invasive methods for early cancer detection. Early identification is crucial effective therapeutic intervention, and techniques have emerged as promising tools to enhance diagnostic accuracy improve patient outcomes. The thoroughly examines advantages, limitations, prospects various approaches, including blood tests, non-blood-based diverse imaging modalities. It discusses biomarkers found in early-stage detection, specifying types associated with each biomarker. tests focus on components saliva, urine, breath alongside current studies future perspectives cancers. Optical covered this include fluorescence near-infrared (NIR) region, bioluminescence imaging, Raman spectroscopy also highlights pros cons ultrasound Additionally, clinical implications using AI both present future, are explored. provides valuable insights researchers clinicians working field
Язык: Английский
Процитировано
2
Heliyon, Год журнала: 2024, Номер 10(11), С. e32115 - e32115
Опубликована: Май 29, 2024
Background and aimsThrough a nested cohort study, we evaluated the diagnostic performance of breath-omics in differentiating between benign malignant breast lesions, assessed multi-omics approach that combines breath-omics, ultrasound radiomics, clinic-omics distinguishing lesions.Materials methodsWe recruited 1,723 consecutive patients who underwent an automated volume scanner (ABVS) examination. Breath samples were collected analyzed by high-pressure photon ionization time-of-flight mass spectrometry (HPPI-TOF-MS) to obtain features. 238 enrolled participants have received pathological confirmation nodules finally. The lesions contoured manually based on ABVS images for radiomics feature calculation. Then, single- models constructed diagnosis via five-fold cross-validation.ResultsThe area under curve (AUC) model was 0.855. In comparison, demonstrated superior cancer, with sensitivity, specificity, AUC 84.1%, 89.9%, 0.946, respectively. comparable Breast Imaging Reporting Data System (BI-RADS) classification senior physician evaluation.ConclusionThe combining metabolites exhaled breath, imaging, basic clinical information exhibits promises be non-invasive reliable tool cancer diagnosis.
Язык: Английский
Процитировано
1
Coatings, Год журнала: 2024, Номер 14(9), С. 1214 - 1214
Опубликована: Сен. 20, 2024
The field of gas sensors has been developing for the last year due to necessity characterizing compounds and, in particular, volatile organic whose detection can be special interest a vast range applications that extend from clinical evaluation environmental monitoring. Among all potential techniques develop sensors, magnetron sputtering emerged as one most suitable methodologies production large-scale uniform coatings, with high packing density and strong adhesion substrate at relatively low temperatures. Furthermore, it presents elevated deposition rates, allows growth thin films purity, permits precise control film thickness, enables simple manufacturing power consumption consequently, costs involved production. This work reviewed current developed through VOCs assessment by gathering relevant scientific works published. A total 10 were considered this work. Additionally, 13 other identified promising targets classified future trends field. Overall, summarizes state-of-the-art technology, allowing community take step forward explore new research areas.
Язык: Английский
Процитировано
1
World Journal of Gastrointestinal Oncology, Год журнала: 2024, Номер 16(6), С. 2300 - 2303
Опубликована: Июнь 14, 2024
Recent decades have seen a concerning surge in carcinogenic diseases, with cancer cases and deaths on the rise globally. Conventional diagnostic methods are often invasive time-consuming, highlighting need for fast, accurate, painless alternatives. Non-invasive exhaled breath analysis emerges as promising solution, over 200 volatile organic compounds (VOCs) detected air, showing potential biomarkers various including cancer. Despite lack of standardized methodologies, advancements analytical instruments expanded detection capabilities, reaching 3500 VOCs. Studies identified specific VOC patterns associated different cancers, offering hope non-invasive diagnosis. Techniques such gas chromatography-mass spectrometry electronic noses show promise distinguishing between healthy individuals patients. However, further research standardization needed to realize full clinical breath-based diagnostics, particularly early challenging cancers like pancreatic
Язык: Английский
Процитировано
0