Autologous blood in the management of ocular surface disorders
World Journal of Experimental Medicine,
Год журнала:
2024,
Номер
14(4)
Опубликована: Окт. 29, 2024
Autologous
blood
therapy
has
emerged
as
a
promising
modality
in
managing
ocular
surface
disorders.
This
review
provides
comprehensive
overview
of
the
current
literature
regarding
use
autologous
disorders,
encompassing
its
physiological
basis,
clinical
applications,
techniques,
challenges,
and
future
perspectives.
The
surface,
comprising
cornea,
conjunctiva,
tear
film,
plays
critical
role
maintaining
visual
function,
disruption
can
lead
to
various
pathological
conditions.
With
rich
composition
growth
factors,
cytokines,
other
bioactive
molecules,
offers
therapeutic
potential
promoting
corneal
wound
healing,
reducing
inflammation,
improving
film
stability.
Clinical
studies
have
demonstrated
efficacy
safety
diverse
including
persistent
epithelial
defects,
neurotrophic
keratopathy,
dry
eye
disease.
However,
challenges
such
variability
treatment
response,
adverse
effects,
optimal
patient
selection
remain
areas
concern.
Further
research
is
needed
elucidate
underlying
mechanisms
action,
refine
protocols,
explore
synergistic
approaches
with
modalities.
Despite
these
holds
promise
valuable
adjunctive
option
for
offering
new
avenues
outcomes
quality
life.
examines
disorders
while
discussing
existing
blood-based
therapies
Current
trials
are
also
summarized,
comparison
between
conventional
eyedrops
attempted.
Finally,
safe
techniques
protocols
medicine
elucidated,
effects
perspectives
this
novel
reviewed.
Язык: Английский
Development of a prediction nomogram for IgG levels among asymptomatic or mild patients with COVID-19
Frontiers in Cellular and Infection Microbiology,
Год журнала:
2024,
Номер
14
Опубликована: Дек. 9, 2024
COVID-19
has
evolved
into
a
seasonal
coronavirus
disease,
characterized
by
prolonged
infection
duration
and
repeated
infections,
significantly
increasing
the
risk
of
patients
developing
long
COVID.
Our
research
focused
on
immune
responses
in
asymptomatic
mild
cases,
particularly
critical
factors
influencing
serum
immunoglobulin
G
(IgG)
levels
their
predictive
value.
Язык: Английский
Research Roundup
Journal of Aesthetic Nursing,
Год журнала:
2024,
Номер
13(4), С. 179 - 180
Опубликована: Июль 2, 2024
In
this
regular
feature,
aesthetic
nurse
Claudia
McGloin
presents
a
brief
synopsis
of
range
recently
published
articles
on
medical
aesthetics.
Research
roundup
aims
to
provide
an
overview,
rather
than
detailed
summary
and
critique,
the
papers
selected.
Should
you
wish
look
at
any
in
more
detail,
full
reference
is
provided
end
each
study
Язык: Английский
The Role of Platelet-Rich Plasma in the Management of Sensorineural Hearing Loss: Current Evidence and Emerging Trends
Cureus,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 4, 2024
Sensorineural
hearing
loss
(SNHL)
is
a
common
form
of
impairment
characterized
by
damage
to
the
inner
ear
or
auditory
nerve,
resulting
in
significant
communication
difficulties
and
reduced
quality
life.
Current
treatment
options,
including
aids,
cochlear
implants,
corticosteroids,
primarily
focus
on
symptom
management
do
not
address
underlying
pathophysiological
damage.
Platelet-rich
plasma
(PRP),
an
autologous
concentrate
rich
platelets
growth
factors,
has
emerged
as
potential
regenerative
therapy
due
its
ability
promote
tissue
repair
cellular
regeneration.
This
review
provides
comprehensive
overview
role
PRP
SNHL,
examining
current
evidence
from
preclinical
clinical
studies.
We
discuss
mechanisms
through
which
may
regeneration
repair,
analyze
efficacy
safety
profile,
explore
innovative
approaches
future
directions
application
for
SNHL.
Despite
promising
preliminary
findings,
further
research
needed
optimize
protocols,
establish
standardized
guidelines,
conduct
large-scale
randomized
controlled
trials
validate
efficacy.
aims
highlight
novel
therapeutic
strategy
treating
SNHL
possible
integration
into
practices,
offering
new
hope
patients
with
this
debilitating
condition.
Язык: Английский
The Effect of Platelet-Rich Plasma and Hyaluronic Acid Nasal Injections in the Treatment of Traumatic Olfactory Dysfunction
Ear Nose & Throat Journal,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 15, 2024
Objective:
Platelet-rich
plasma
(PRP)
has
been
injected
into
the
olfactory
cleft
to
treat
dysfunction
related
coronavirus
disease
2019.
In
this
study,
we
aimed
evaluate
effect
of
PRP
combined
with
hyaluronic
acid
(HA)
nasal
injection
in
treatment
traumatic
dysfunction.
Methods:
Patients
who
had
lost
function
after
experiencing
head
trauma
and
were
willing
receive
HA
injections
for
enrolled.
Before
injection,
10
cc
blood
was
drawn
from
patients.
The
a
centrifuge
tube
processing,
finally,
5
mixed
out
using
an
empty
syringe.
upper
part
middle
septum
medial
side
turbinate
patient’s
cavity
under
endoscope.
each
patient
evaluated
by
phenyl
ethyl
alcohol
(PEA)
odor
detection
threshold
test
before
at
both
1
3
months
traditional
Chinese
version
University
Pennsylvania
Smell
Identification
Test
injection.
Results:
A
total
28
patients
received
between
August
December
2023
came
back
evaluation
effect.
all,
20
(71.4%)
felt
their
improved
month
24
(85.7%)
reported
bilateral
or
unilateral
PEA
decreased
22
(78.6%)
15
(53.6%)
Conclusions:
Our
results
show
that
associated
favored
patient-reported
outcomes
Язык: Английский