The Potential Role of Adipose-Derived Stem Cells in Regeneration of Peripheral Nerves DOI Creative Commons
PM Sunil, Sivan Padma Priya, Nada Tawfig Hashim

и другие.

Neurology International, Год журнала: 2025, Номер 17(2), С. 23 - 23

Опубликована: Фев. 6, 2025

Peripheral nerve injuries are common complications in surgical and dental practices, often resulting functional deficiencies reduced quality of life. Current treatment choices, such as autografts, have limitations, including donor site morbidity suboptimal outcomes. Adipose-derived stem cells (ADSCs) shown assuring regenerative potential due to their accessibility, ease harvesting propagation, multipotent properties. This review investigates the therapeutic ADSCs peripheral regeneration, focusing on use bioengineered conduits supportive microenvironments. The analysis is constructed published case reports, organized reviews, clinical trials from Phase I III that investigate managing injuries, emphasizing both orofacial applications. findings highlight advantages promoting secretion angiogenic neurotrophic factors, support for cellular persistence, supplementing scaffold-based tissue repair. capabilities offer a novel approach augmenting repair recovery. accessibility adipose minimally invasive nature ADSC further encourage its prospective application an autologous cell source medicine. Future research needed ascertain standardized protocols optimize outcomes, paving way become mainstay regeneration.

Язык: Английский

Exosomes in Regulating miRNAs for Biomarkers of Neurodegenerative Disorders DOI
Azhagu Madhavan Sivalingam,

Darshitha D Sureshkumar

Molecular Neurobiology, Год журнала: 2025, Номер unknown

Опубликована: Фев. 7, 2025

Язык: Английский

Процитировано

1
The Potential Role of Adipose-Derived Stem Cells in Regeneration of Peripheral Nerves DOI Creative Commons
PM Sunil, Sivan Padma Priya, Nada Tawfig Hashim

и другие.

Neurology International, Год журнала: 2025, Номер 17(2), С. 23 - 23

Опубликована: Фев. 6, 2025

Peripheral nerve injuries are common complications in surgical and dental practices, often resulting functional deficiencies reduced quality of life. Current treatment choices, such as autografts, have limitations, including donor site morbidity suboptimal outcomes. Adipose-derived stem cells (ADSCs) shown assuring regenerative potential due to their accessibility, ease harvesting propagation, multipotent properties. This review investigates the therapeutic ADSCs peripheral regeneration, focusing on use bioengineered conduits supportive microenvironments. The analysis is constructed published case reports, organized reviews, clinical trials from Phase I III that investigate managing injuries, emphasizing both orofacial applications. findings highlight advantages promoting secretion angiogenic neurotrophic factors, support for cellular persistence, supplementing scaffold-based tissue repair. capabilities offer a novel approach augmenting repair recovery. accessibility adipose minimally invasive nature ADSC further encourage its prospective application an autologous cell source medicine. Future research needed ascertain standardized protocols optimize outcomes, paving way become mainstay regeneration.

Язык: Английский

Процитировано

0