MRS Advances, Год журнала: 2024, Номер unknown
Опубликована: Дек. 2, 2024
Язык: Английский
Journal of Macromolecular Science Part B, Год журнала: 2025, Номер unknown, С. 1 - 12
Опубликована: Янв. 9, 2025
Colon cancer is still a significant cause of cancer-related deaths and, therefore, new treatment approaches are required. As naturally derived polysaccharide, Chitosan has become one the most promising materials in polymer-based drug delivery systems because its outstanding biocompatibility, biodegradability, and pH-responsive release. This review explores expanding roles chemical modifications colon therapy, emphasizing relationship between macromolecular interactions structure-property dynamics. Recent progress Chitosan-based nanocarriers, including nanoparticles, nanogels hybrid systems, highlights their potential to overcome multidrug resistance minimize off-target toxicity. These advancements closely aligned with developments precision medicine, incorporating stimuli-responsive components targeted ligands for enhanced efficacy. While preclinical clinical studies yield results, critical challenges such as scalability, reproducibility regulatory compliance remain obstacles translation. emphasizes transformative addressing therapeutic barriers treatment. Looking ahead, future should focus on utilizing cutting-edge technologies, artificial intelligence 3D bioprinting, enhance formulations develop personalized solutions that more effective tailored individual needs.
Язык: Английский
Процитировано
1
International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 140903 - 140903
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
0
Frontiers in Materials, Год журнала: 2025, Номер 12
Опубликована: Март 4, 2025
Chitin is the second most abundant polysaccharide on Earth, after cellulose, and it mainly obtained from shells of crustaceans. While chitin currently derived shrimp shells, there a growing interest in commercializing sourced insects. This review compares various sources, including crustaceans, insects, fungi, mollusks, based several factors: purity, molecular weight, crystallinity, cost, sustainability. Although crustaceans yield higher amounts exhibit better insects present significant advantages terms sustainability, ease extraction, lower impurity levels. emerging as sustainable alternative due to its simpler extraction processes reduced environmental impact. work highlights increasing potential reliable source for production.
Язык: Английский
Процитировано
0
Polysaccharides, Год журнала: 2025, Номер 6(2), С. 26 - 26
Опубликована: Апрель 1, 2025
As a biodegradable material, chitin possesses exceptional physical and chemical properties, making it valuable in various industrial sectors. Compared to chitin, its derivative, chitosan, offers even more versatile applications due higher solubility reactivity. the key precursor for chitosan production, is typically harvested from shrimp crab exoskeletons. However, quest alternative sources has intensified reduce reliance on crustacean-derived chitin. Black soldier fly (BSF, Hermetia illucens), particularly puparium, emerged as promising alternative, though considered waste. In this study, we investigated different combinations sequences of extraction treatments BSF puparium. The results demonstrate that sequential demineralization (DM), deproteination (DP), decolorization (DC) produce with lowest ash, lipid, protein contents—approximately 1.01%, 1.99%, 3.01%, respectively, yielding degrees DM DP at 94.77% 92.24%, purity 93.98%. contrast, combining DC following treatment facilitates partial transformation degree deacetylation (DD) 65.90%, offering direct producing without an additional process.
Язык: Английский
Процитировано
0
Sustainable Chemistry and Pharmacy, Год журнала: 2025, Номер 45, С. 102013 - 102013
Опубликована: Апрель 6, 2025
Язык: Английский
Процитировано
0
Gels, Год журнала: 2025, Номер 11(4), С. 291 - 291
Опубликована: Апрель 15, 2025
Chitin and its deacetylated derivative, chitosan, are biopolymers of significant interest due to their biocompatibility, biodegradability, wide-ranging applications in biomedical, environmental, industrial fields. The exploitation crustaceans as the traditional source chitosan raises concerns about overfishing ecological sustainability. Modern insect farming, contrast, offers advantages such a circular insect-based economy leading reduced carbon footprint. This review explores potential insect-derived an alternative, emphasizing environmental benefits during production, functional properties, applications. Several aspects key analytical techniques for chitin characterization, including photometric, chromatographic, spectroscopic methods, also discussed. underscores versatility biomedical applications, wound healing drug delivery, well agriculture, packaging, wastewater treatment.
Язык: Английский
Процитировано
0
Foods, Год журнала: 2025, Номер 14(8), С. 1382 - 1382
Опубликована: Апрель 17, 2025
The increasing global population, projected to exceed 9.1 billion by 2050, presents a critical challenge for sustainable food production. Edible insects have emerged as promising alternative protein source due their high nutritional value, low environmental footprint, and efficient resource utilization. This review explores the opportunities challenges of integrating edible into systems. Benefits include content quality, greenhouse gas emissions, low-cost production, ability thrive on organic waste. Furthermore, insect cultivation requires significantly less land water compared traditional livestock. are nutritionally rich, containing substantial amounts essential amino acids, unsaturated fatty minerals. However, barriers widespread adoption persist, such cultural perceptions, regulatory hurdles, potential allergenicity, biological chemical contamination. standardizing rearing practices ensuring safety broader adoption. While represent nutritious, feed, there lot variables that not been fully investigated. Only after further research, results, solutions relatively easy apply might be considered source. Considering may arise more intensive research is highly advised.
Язык: Английский
Процитировано
0
Cellulose, Год журнала: 2024, Номер 31(17), С. 10143 - 10163
Опубликована: Окт. 21, 2024
Язык: Английский
Процитировано
1
Heliyon, Год журнала: 2024, Номер 10(13), С. e33642 - e33642
Опубликована: Июнь 28, 2024
Chitosan is a biocompatible, non-toxic and renewable natural basic polysaccharide that can be cross-linked reacted with Ce(IV) to form physiologically active chitosan-Ce(IV) complex. To investigate this novel complex its potential hydrolyze phosphate ester bonds, chitosan-cerium microspheres resin (CS-CCMR) was prepared from chitosan ceric ammonium nitrate by reversed-phase suspension cross-linking polymerization. CS-CCMR characterized, ability disodium p-nitrobenzene (PNPP2Na) organophosphorus pesticides investigated, the hydrolytic mechanism explored. composed of dark yellow smooth surfaces dense pores. It found contained 4.507 mg/g Ce(IV), indicating coordination polymerization between successful. The presence in confirmed multiple analytical methods it mediated nitrogen atom amino group oxygen hydroxyl chitosan. shown efficiently hydrolyzed bonds PNPP2Na five pesticides. Hydrolysis potentially accomplished charge neutralization nucleophilic substitution. parathion degradation involves modification nitro give aminoparathion, followed cleavage P–O bond generate diazinphos. Consequently, exhibits great efficiency for hydrolysis expected developed as an agent reduce possibility contamination fruit vegetable drinks
Язык: Английский
Процитировано
0
Elsevier eBooks, Год журнала: 2024, Номер unknown, С. 309 - 362
Опубликована: Ноя. 29, 2024
Язык: Английский
Процитировано
0