Frontiers in Nutrition,
Год журнала:
2024,
Номер
11
Опубликована: Ноя. 12, 2024
Sensitive
detection
of
gallic
acid
(GA)
in
foods
is
great
significance
for
assessing
the
antioxidant
properties
products
and
ensuring
consumer
health.
In
this
work,
a
simple
electrochemical
sensor
was
conveniently
fabricated
by
integrating
vertically-ordered
mesoporous
silica
film
(VMSF)
with
electrochemically
reduced
graphene
oxide
(ErGO)
nitrogen
quantum
dots
(NGQDs)
nanocomposite,
enabling
sensitive
GA
food
sample.
A
water-soluble
mixture
(GO)
NGQDs
drop-cast
onto
common
carbon
electrode,
glassy
electrode
(GCE),
followed
rapid
growth
VMSF
using
an
assisted
self-assembly
method
(EASA).
The
negative
voltage
applied
during
facilitated
situ
reduction
GO
to
ErGO.
synergistic
effects
ErGO,
NGQDs,
nanochannels
led
nearly
tenfold
enhancement
signal
compared
that
obtained
on
electrodes
modified
either
ErGO
or
alone.
realized
linear
concentration
range
from
0.1
10
μM,
100
μM.
limit
(LOD),
determined
based
signal-to-noise
ratio
three
(
S
/
N
=
3),
found
be
81
nM.
Combined
size-exclusion
property
VMSF,
demonstrated
high
selectivity,
making
it
suitable
samples.
Molecules,
Год журнала:
2024,
Номер
29(20), С. 4880 - 4880
Опубликована: Окт. 15, 2024
Simple
development
of
an
electrochemiluminescence
(ECL)
immunosensor
for
convenient
detection
tumor
biomarker
is
great
significance
early
cancer
diagnosis,
treatment
evaluation,
and
improving
patient
survival
rates
quality
life.
In
this
work,
demonstrated
based
on
enhanced
ECL
signal
boosted
by
nanochannel-confined
Au
nanomaterial,
which
enables
sensitive
the
biomarker-carcinoembryonic
antigen
(CEA).
Vertically-ordered
mesoporous
silica
film
(VMSF)
with
a
nanochannel
array
amine
groups
was
rapidly
grown
simple
low-cost
indium
tin
oxide
(ITO)
electrode
using
electrochemically
assisted
self-assembly
(EASA)
method.
nanomaterials
were
confined
in
situ
VMSF
through
electrodeposition,
catalyzed
both
conversion
dissolved
oxygen
(O
Frontiers in Chemistry,
Год журнала:
2024,
Номер
12
Опубликована: Ноя. 11, 2024
Disposable
electrochemical
biosensors
with
high
sensitivity
are
very
fit
for
point-of-care
testing
in
clinical
diagnosis.
Herein,
amino-functionalized,
vertically
ordered
mesoporous
silica
films
(NH
Frontiers in Chemistry,
Год журнала:
2024,
Номер
12
Опубликована: Окт. 25, 2024
Development
of
simple
solid-phase
electrochemiluminescence
(ECL)
immunosensor
with
convenient
fabrication
for
high-performance
detection
tumor
biomarkers
is
crucial.
Herein,
a
ECL
immunoassay
was
constructed
based
on
bipolar
silica
nanochannel
film
(bp-SNA)
modified
electrode
highly
sensitive
carbohydrate
antigen
125
(CA
125).
Inexpensive
and
readily
available
indium
tin
oxide
(ITO)
used
as
the
supporting
growth
bp-SNA.
bp-SNA
consists
bilayer
SNA
different
functional
groups
charge
properties,
including
negatively
charged
inner
layer
(n-SNA)
positively
outer
(p-SNA).
The
nanochannels
were
immobilization
emitter
tris(bipyridine)ruthenium(II),
while
surface
utilized
constructing
immunorecognition
interface.
Due
to
dual
electrostatic
interaction
composed
attraction
from
n-SNA
repulsion
p-SNA,
could
be
stably
confined
within
bp-SNA,
providing
stable
high
signals
electrode.
After
amino
derivatized
aldehyde
groups,
recognition
antibodies
covalently
immobilized,
an
obtained
after
blocking
nonspecific
sites.
When
CA
binds
interface,
formed
complex
reduces
diffusion
co-reactant
tripropylamine
(TPrA)
electrode,
decreasing
signal.
Based
this
mechanism,
can
achieve
125.
linear
range
0.01
100
U/mL,
limit
4.7
mU/mL.
in
serum
also
achieved.
construction
has
advantages
fabrication,
stability
immobilized
emitter,
selectivity,
making
it
suitable
detection.
Frontiers in Nutrition,
Год журнала:
2024,
Номер
11
Опубликована: Ноя. 12, 2024
Sensitive
detection
of
gallic
acid
(GA)
in
foods
is
great
significance
for
assessing
the
antioxidant
properties
products
and
ensuring
consumer
health.
In
this
work,
a
simple
electrochemical
sensor
was
conveniently
fabricated
by
integrating
vertically-ordered
mesoporous
silica
film
(VMSF)
with
electrochemically
reduced
graphene
oxide
(ErGO)
nitrogen
quantum
dots
(NGQDs)
nanocomposite,
enabling
sensitive
GA
food
sample.
A
water-soluble
mixture
(GO)
NGQDs
drop-cast
onto
common
carbon
electrode,
glassy
electrode
(GCE),
followed
rapid
growth
VMSF
using
an
assisted
self-assembly
method
(EASA).
The
negative
voltage
applied
during
facilitated
situ
reduction
GO
to
ErGO.
synergistic
effects
ErGO,
NGQDs,
nanochannels
led
nearly
tenfold
enhancement
signal
compared
that
obtained
on
electrodes
modified
either
ErGO
or
alone.
realized
linear
concentration
range
from
0.1
10
μM,
100
μM.
limit
(LOD),
determined
based
signal-to-noise
ratio
three
(
S
/
N
=
3),
found
be
81
nM.
Combined
size-exclusion
property
VMSF,
demonstrated
high
selectivity,
making
it
suitable
samples.
