Nanotechnology-Based Wearable Electrochemical Biosensor for Disease Diagnosis
ACS Sensors,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 4, 2025
Recently,
flexible
electronics
have
significantly
transformed
information
and
communications
technology
(ICT).
In
particular,
wearable
devices,
via
integration
with
attachable
biosensors,
driven
the
development
of
new
types
biosensors
diagnostic
devices
for
point-of-care
testing
(POCT).
Moreover,
electrochemical
can
be
applied
to
diagnose
diseases
in
real
time
based
on
synergistic
effect
generated
from
incorporation
technique.
Besides,
improve
sensitivity
while
retaining
their
wearability,
novel
nanomaterials
nanotechnologies
been
introduced.
this
review,
recent
studies
nanotechnology-based
accurate
disease
diagnosis
are
discussed.
First,
widely
used
techniques
developing
electrodes,
including
nanolithography-
nano/microneedle-based
patches,
presented.
Next,
latest
such
as
diabetes
dermatitis
discussed
by
categorizing
into
categories.
Finally,
review
explores
research
trends
application
nanotechnology-enabled
nanopatterning
nano/microneedle
technologies
biosensors.
This
suggests
approaches
methods
real-time
under
POCT
applications.
Язык: Английский
Global practices of tear fluid collection, storage, and molecular analysis – A questionnaire by the Tear Research Network
Contact Lens and Anterior Eye,
Год журнала:
2025,
Номер
unknown, С. 102388 - 102388
Опубликована: Март 1, 2025
Язык: Английский
Advanced Microfluidic‐Based Wearable Electrochemical Sensors for Continuous Biochemical Monitoring
Advanced Electronic Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 18, 2025
Abstract
Microfluidic‐based
wearable
electrochemical
sensors
represent
a
transformative
approach
to
non‐invasive,
real‐time
health
monitoring
through
continuous
biochemical
analysis
of
body
fluids
such
as
sweat,
saliva,
and
interstitial
fluid.
These
systems
offer
significant
potential
for
personalized
healthcare
disease
management
by
enabling
detection
key
biomarkers.
However,
challenges
remain
in
optimizing
microfluidic
channel
design,
ensuring
consistent
biofluid
collection,
balancing
high‐resolution
fabrication
with
scalability,
integrating
flexible
biocompatible
materials,
establishing
standardized
validation
protocols.
This
review
explores
advancements
techniques,
integrated
that
have
improved
sensitivity,
selectivity,
durability.
Conventional
photolithography,
3D
printing,
laser‐based
methods
are
compared,
highlighting
their
mechanisms,
advantages,
trade‐offs
production.
The
application
section
summarizes
strategies
overcome
variability
composition,
sensor
drift,
user
adaptability
innovative
solutions
hybrid
material
integration,
self‐powered
systems,
AI‐assisted
data
analysis.
By
analyzing
recent
breakthroughs,
this
paper
outlines
critical
pathways
expanding
technologies
achieving
seamless
operation
diverse
real‐world
settings,
paving
the
way
new
era
digital
health.
Язык: Английский
Areas for improvement in the current care and treatment of dry eye disease
Expert Review of Ophthalmology,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 14, 2025
Язык: Английский
Enhancing glaucoma care with smart contact lenses: An overview of recent developments
Biomedical Microdevices,
Год журнала:
2025,
Номер
27(2)
Опубликована: Апрель 21, 2025
Abstract
Glaucoma
is
a
leading
cause
of
irreversible
blindness
worldwide,
affecting
millions
individuals
due
to
its
progressive
damage
the
optic
nerve,
often
caused
by
elevated
intraocular
pressure
(IOP).
Conventional
methods
IOP
monitoring,
such
as
tonometry,
provide
sporadic
and
inaccurate
readings
fluctuations
throughout
day,
leaving
significant
gaps
in
diagnosis
treatment.
This
review
explores
transformative
potential
smart
contact
lenses
equipped
with
continuous
monitoring
therapeutic
capabilities.
These
integrate
advanced
materials
graphene,
nanogels,
magnetic
oxide
nanosheets
alongside
sophisticated
biosensing
wireless
communication
systems.
By
offering
continuous,
real-time
data,
these
can
detect
subtle
immediate
feedback
patients
clinicians.
Moreover,
drug-eluting
capabilities
embedded
present
groundbreaking
approach
glaucoma
therapy
improving
medication
adherence
providing
controlled
drug
release
directly
eye.
Beyond
management,
innovations
also
pave
way
for
biochemical
markers
other
ocular
diseases.
Challenges
biocompatibility,
long-term
wearability,
affordability
remain,
but
integration
cutting-edge
technologies
signifies
paradigm
shift
care.
developments
hold
immense
promise
advancing
personalized
medicine,
patient
outcomes,
mitigating
global
burden
blindness.
Язык: Английский
Electrochemically Active Materials for Tissue-Interfaced Soft Biochemical Sensing
ACS Sensors,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 21, 2025
Tissue-interfaced
soft
biochemical
sensing
represents
a
crucial
approach
to
personalized
healthcare
by
employing
electrochemically
active
materials
monitor
signals
at
the
tissue
interface
in
real
time,
either
noninvasively
or
through
implantation.
These
sensors
can
be
integrated
with
various
biological
tissues,
such
as
neural,
gastrointestinal,
ocular,
cardiac,
skin,
muscle,
and
bone,
adapting
their
unique
mechanical
environments.
Sensors
like
conductive
polymers,
composites,
metals,
metal
oxides,
carbon-based
nanomaterials
have
demonstrated
capabilities
applications,
continuous
glucose
monitoring,
neural
activity
mapping,
real-time
metabolite
detection,
enhancing
diagnostics
treatment
monitoring
across
range
of
medical
fields.
Next-generation
tissue-interfaced
biosensors
that
enable
multimodal
multiplexed
measurement
markers
physiological
parameters
could
transformative
for
medicine,
allowing
high-resolution,
time-resolved
historical
an
individual's
health
status.
In
this
review,
we
summarize
current
trends
field
provide
insights
into
challenges
future
trajectory
sensors,
highlighting
potential
revolutionize
medicine
improve
patient
outcomes.
Язык: Английский