Effects of Damage to the Integrity of the Left Dual-Stream Frontotemporal Network Mediated by the Arcuate Fasciculus and Uncinate Fasciculus on Acute/Subacute Post-Stroke Aphasia

Brain Sciences, Год журнала: 2023, Номер 13(9), С. 1324 - 1324

Опубликована: Сен. 14, 2023

(1) Background: To investigate the correlation between integrity of left dual-stream frontotemporal network mediated by arcuate fasciculus (AF) and uncinate (UF), acute/subacute post-stroke aphasia (PSA). (2) Methods: Thirty-six patients were recruited received both a language assessment diffusion tensor imaging (DTI) scan. Correlations indices in bilateral LSAF/UF performance analyzed with analyses. Multiple linear regression analysis was also implemented to effects on performance. (3) Results: Correlation analyses showed that indices, including mean fractional anisotropy (FA) values fiber number LSAF rather than UF significantly positively associated domain scores (p < 0.05). revealed an independent positive association FA value percentage score subsets. In addition, no interaction effect found > (4) Conclusions: The LSAF, but not UF, might play important roles supporting residual ability individuals PSA; simultaneous disruption would result more severe damage either pathway alone.

Язык: Английский

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Diffusion MRI Fiber Tractography and Benzodiazepine SPECT Imaging for Assessing Neural Damage to the Language Centers in an Elderly Patient after Successful Reperfusion Therapy

Geriatrics, Год журнала: 2024, Номер 9(2), С. 30 - 30

Опубликована: Март 1, 2024

Background: Intravenous thrombolysis and mechanical thrombectomy are the first-line reperfusion therapies for acute ischemic stroke. Here, we describe utility of diffusion magnetic resonance imaging (MRI) fiber tractography 123I-iomazenil benzodiazepine receptor single-photon emission computed tomography to estimate prognosis post-stroke aphasia after successful therapy. Case report: An 81-year-old man was admitted hospital approximately 3.5 h onset symptoms, including decreased consciousness, right hemiparesis, aphasia. MRI revealed cerebral infarction due M1 segment occlusion. alteplase followed by endovascular resulted in recanalization left middle artery territory. A subsequent showed no new or hemorrhagic lesions. Although patient’s motor hemiparesis gradually recovered, persisted. Diffusion performed 2 weeks admission partial injury arcuate fasciculus, indicated lower fractional anisotropy values than on contralateral side. density also detected perisylvian temporoparietal cortices. The patient clear signs further improvement chronic stage discharged a nursing home 3 months. Conclusions: application functional neuroimaging techniques assess neuronal damage primary brain regions therapy large-vessel occlusion may allow an accurate This have direct clinical implication navigating subacute-to-chronic phases rehabilitative care.

Язык: Английский

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The Role of the Right Hemispheric Homologous Language Pathways in Recovery from Post-Stroke Aphasia: A Systematic Review

Psychiatry Research Neuroimaging, Год журнала: 2024, Номер 343, С. 111866 - 111866

Опубликована: Авг. 2, 2024

Язык: Английский

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Poor Spontaneous Recovery of Aphemia Accompanied by Damage to the Anterior Segment of the Left Arcuate Fasciculus: A Case Report

Brain Sciences, Год журнала: 2022, Номер 12(9), С. 1253 - 1253

Опубликована: Сен. 16, 2022

Aphemia is a rare and special type of speech disorder, the mechanisms underlying occurrence recovery remain unclear. Here, we present clinical case poor spontaneous aphemia, with anterior segment left arcuate fasciculus server damaged posterior intact, as detected by diffusion tensor imaging. could be caused disruption cortical subcortical language circuits. In particular, our data support view that damage to may result in from production deficits an intact seems crucial for supporting residual comprehension ability patients post-stroke aphasia. Collectively, these imply importance during disorder subacute stage stroke.

Язык: Английский

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Predicting Language Function Post-Stroke: A Model-Based Structural Connectivity Approach

Neurorehabilitation and neural repair, Год журнала: 2024, Номер 38(6), С. 447 - 459

Опубликована: Апрель 11, 2024

Background The prediction of post-stroke language function is essential for the development individualized treatment plans based on personal recovery potential aphasic stroke patients. Objective To establish a framework integrating information connectivity disruption network routinely collected clinical magnetic resonance (MR) images into Random Forest modeling to predict function. Methods Language was assessed in 76 patients from Non-Invasive Repeated Therapeutic Stimulation Aphasia Recovery trial, using Token Test (TT), Boston Naming (BNT), and Semantic Verbal Fluency (sVF) as primary outcome measures. Individual infarct masks were superimposed onto diffusion tensor imaging tractogram reference set calculate Change Connectivity scores language-relevant gray matter regions estimates structural disruption. Multivariable models derived Results explained moderate high amount variance at baseline follow-up TT (62.7% 76.2%), BNT (47.0% 84.3%), sVF (52.2% 61.1%). Initial non-verbal cognitive ability most important variables additional variance, resulting error increase up 12.8% with variable omission. Left middle temporal gyrus (12.8%) supramarginal (9.8%) identified among nodes. Conclusion adds predictive value beyond lesion volume, initial function, ability. Obtaining routine MR constitutes significant advancement toward practical application.

Язык: Английский

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Prediction Models Of The Aphasia Severity After Stroke By Lesion Load Of Cortical Language Areas and White Matter Tracts: An Atlas-based Study.

Brain Research Bulletin, Год журнала: 2024, Номер 217, С. 111074 - 111074

Опубликована: Сен. 7, 2024

Язык: Английский

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Advances in diagnostic imaging and interventional treatment of aphasia after basal ganglia stroke

Neuroscience, Год журнала: 2024, Номер 564, С. 160 - 170

Опубликована: Ноя. 16, 2024

Язык: Английский

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