Research Progress on Glioma Microenvironment and Invasiveness Utilizing Advanced Multi-Parametric Quantitative MRI DOI Open Access
Dandan Song, Guoguang Fan, Miao Chang

и другие.

Cancers, Год журнала: 2024, Номер 17(1), С. 74 - 74

Опубликована: Дек. 29, 2024

Magnetic resonance imaging (MRI) currently serves as the primary diagnostic method for glioma detection and monitoring. The integration of neurosurgery, radiation therapy, pathology, radiology in a multi-disciplinary approach has significantly advanced its diagnosis treatment. However, prognosis remains unfavorable due to treatment resistance, inconsistent response rates, high recurrence rates after surgery. These factors are closely associated with complex molecular characteristics tumors, internal heterogeneity, relevant external microenvironment. complete removal gliomas presents challenges their infiltrative growth pattern along white matter fibers perivascular space. Therefore, it is crucial comprehensively understand features analyze tumor heterogeneity order accurately characterize quantify invasion range. multi-parameter quantitative MRI technique provides an opportunity investigate microenvironment aggressiveness tumors at cellular, blood perfusion, cerebrovascular levels. this review examines current applications research explores prospects future development.

Язык: Английский

A New Tool for Extracting Static and Dynamic Parameters from [18F]F-DOPA PET/CT in Pediatric Gliomas DOI Open Access

Michele Mureddu,

Thomas Funck, Giovanni Morana

и другие.

Journal of Clinical Medicine, Год журнала: 2024, Номер 13(20), С. 6252 - 6252

Опубликована: Окт. 19, 2024

: PET imaging with [

Язык: Английский

Процитировано

0

Head and Neck Squamous Cell Carcinoma: Insights from Dual-Energy Computed Tomography (DECT) DOI Creative Commons
Eleonora Bicci, A Finizio, Leonardo Calamandrei

и другие.

Tomography, Год журнала: 2024, Номер 10(11), С. 1780 - 1797

Опубликована: Ноя. 11, 2024

Head and neck cancer represents the seventh most common neoplasm worldwide, with squamous cell carcinoma being represented histologic variant. The rising incidence of neoplastic pathology this district, coupled drastic changes in its epidemiology over past decades, have posed significant challenges to physicians worldwide terms diagnosis, prognosis, treatment. In order meet these challenges, a considerable amount effort has been spent by authors recent literature explore new technologies their possible employment for better diagnostic prognostic definition head (HNSCC). Among technologies, growing interest gathering around applications dual-energy computed tomography (DECT) pathology. Dual-energy utilizes two distinct X-ray energy spectra obtain datasets single scan, allowing material differentiation based on unique attenuation profiles. DECT offers key benefits such as enhanced contrast resolution, reduced beam-hardening artifacts, precise iodine quantification through monochromatic reconstructions. It also creates decomposition images, like maps, aiding tumor characterization therapy assessment. This paper aims summarize findings use HNSCC, providing comprehensive overview aid further research exploration field.

Язык: Английский

Процитировано

0

Risk of Postoperative Hemorrhage After Glioma Surgery in Patients with Preoperative Acetylsalicylic Acid DOI Open Access

Anatoli Pinchuk,

Nikolay Tonchev, Claudia A. Dumitru

и другие.

Cancers, Год журнала: 2024, Номер 16(22), С. 3845 - 3845

Опубликована: Ноя. 15, 2024

Patients with gliomas show an increased risk of spontaneous hemorrhages throughout the disease. Simultaneously, number patients taking acetylsalicylic acid (ASA) for primary and secondary prophylaxis is rising in daily clinical practice, interrupting ASA intake before elective or emergency intracranial surgery not always feasible. This study aims to evaluate risks associated continuing use perioperatively while focusing on hemorrhage potential thromboembolic events that may arise from discontinuing ASA, particularly multimorbid undergoing glioma surgery.

Язык: Английский

Процитировано

0

Efficient and Accurate Brain Tumor Classification Using Hybrid MobileNetV2–Support Vector Machine for Magnetic Resonance Imaging Diagnostics in Neoplasms DOI Creative Commons
Mohammed Jajere Adamu, Halima Bello Kawuwa, Qiang Li

и другие.

Brain Sciences, Год журнала: 2024, Номер 14(12), С. 1178 - 1178

Опубликована: Ноя. 25, 2024

Background/Objectives: Magnetic Resonance Imaging (MRI) plays a vital role in brain tumor diagnosis by providing clear visualization of soft tissues without the use ionizing radiation. Given increasing incidence tumors, there is an urgent need for reliable diagnostic tools, as misdiagnoses can lead to harmful treatment decisions and poor outcomes. While machine learning has significantly advanced medical diagnostics, achieving both high accuracy computational efficiency remains critical challenge. Methods: This study proposes hybrid model that integrates MobileNetV2 feature extraction with Support Vector Machine (SVM) classifier classification tumors. The was trained validated using Kaggle MRI dataset, which includes 7023 images categorized into four types: glioma, meningioma, pituitary tumor, no tumor. MobileNetV2’s efficient architecture leveraged extraction, SVM used enhance accuracy. Results: proposed showed excellent results, Area Under Curve (AUC) scores 0.99 0.97 1.0 tumors class. These findings highlight MobileNetV2-SVM not only improves but also reduces overhead, making it suitable broader clinical use. Conclusions: demonstrates substantial potential enhancing diagnostics offering balance precision efficiency. Its ability maintain while operating efficiently could better outcomes practice, particularly resource limited settings.

Язык: Английский

Процитировано

0

Progressive Quadriparesis of a Toddler with a Posterior Cranial Fossa Arachnoid Cyst (AC): Illustrative Case Report and Narrative Literature Review DOI Creative Commons

Thanos Vassilopoulos,

Marianna Miliaraki, Christos Tsitsipanis

и другие.

Children, Год журнала: 2024, Номер 11(12), С. 1463 - 1463

Опубликована: Ноя. 29, 2024

Background/Objectives: Intracranial arachnoid cysts (ACs) may be congenital, primary, or secondary due to trauma. These are benign, contain cerebrospinal fluid (CSF), and classified based on location, size, their clinical symptomatology. They uncommon lesions in children, rarely leading severe mass-effect neurological Methods: The present report describes a 30-month-old female presenting with quadriparesis. An emergency magnetic resonance imaging (MRI) study revealed the presence of primary intracranial cyst posterior cranial fossa, exerting significant pressure medulla oblongata cervical portion spinal cord, displacing them dorsally, remnant diameter 2.5 mm. Results: This benign malformation located crucial area might have been complicated by deterioration required prompt intervention, so patient underwent suboccipital craniectomy sitting position, along neurosurgical procedure, which established lasting communication channel between basal cisterns. led favorable outcome. Conclusions: Up report, postoperative complete resolution quadriparesis fossa has not reported. At present, no therapeutic modality as definitive standard care for pediatric ACs, management raises great deal controversy among neurosurgeons. narrative literature review integrates various perspectives regarding ACs possible treatment approaches that currently available.

Язык: Английский

Процитировано

0

“Beyond the Knife”—Applying Theranostic Technologies to Enhance Outcomes in Neurosurgical Oncology DOI Creative Commons

Santosh Guru,

Fred C. Lam,

Amirhossein Akhavan-Sigari

и другие.

Brain Sciences, Год журнала: 2024, Номер 14(12), С. 1253 - 1253

Опубликована: Дек. 13, 2024

The current standard of care for brain tumor management includes maximal safe surgical resection followed by concurrent chemotherapy and radiation therapy. Recent advances in image-guided techniques have enhanced the precision resections, yet there remains a critical need innovative technologies to further improve patient outcomes. Techniques such as fluorescence neurosurgery combination with stereotactic radiosurgery improved outcomes patients tumors. In this article Brain Science’s Special Issue Advances Translational Neuro-Oncology, we review use treatment addition, summarize emerging theranostic nanoparticles delivery diagnostic therapeutic enable neurosurgeon perform more precise resections operating room, specifically target existing novel treatments cells, augment efficacy radiosurgery. These translational tools will allow neurosurgeons, neuro-oncologists, oncologists go “beyond knife” survival patients.

Язык: Английский

Процитировано

0

Involvement of the left uncinate fasciculus in the amyotrophic lateral sclerosis: an exploratory longitudinal multi-modal neuroimaging and neuropsychological study DOI
Sadegh Ghaderi, Farzad Fatehi, Sanjay Kalra

и другие.

Brain Structure and Function, Год журнала: 2024, Номер 230(1)

Опубликована: Дек. 17, 2024

Язык: Английский

Процитировано

0

Research Progress on Glioma Microenvironment and Invasiveness Utilizing Advanced Multi-Parametric Quantitative MRI DOI Open Access
Dandan Song, Guoguang Fan, Miao Chang

и другие.

Cancers, Год журнала: 2024, Номер 17(1), С. 74 - 74

Опубликована: Дек. 29, 2024

Magnetic resonance imaging (MRI) currently serves as the primary diagnostic method for glioma detection and monitoring. The integration of neurosurgery, radiation therapy, pathology, radiology in a multi-disciplinary approach has significantly advanced its diagnosis treatment. However, prognosis remains unfavorable due to treatment resistance, inconsistent response rates, high recurrence rates after surgery. These factors are closely associated with complex molecular characteristics tumors, internal heterogeneity, relevant external microenvironment. complete removal gliomas presents challenges their infiltrative growth pattern along white matter fibers perivascular space. Therefore, it is crucial comprehensively understand features analyze tumor heterogeneity order accurately characterize quantify invasion range. multi-parameter quantitative MRI technique provides an opportunity investigate microenvironment aggressiveness tumors at cellular, blood perfusion, cerebrovascular levels. this review examines current applications research explores prospects future development.

Язык: Английский

Процитировано

0