The conundrum of the connection between severe psychiatric disorders and dementia

Dementia & Neuropsychologia, Год журнала: 2025, Номер 19

Опубликована: Янв. 1, 2025

ABSTRACT. Psychiatric disorders have been recognized as important risk factors for neurodegenerative diseases, especially dementia. The strength of association varies among different psychiatric conditions, being more pronounced in severe mental illnesses, i.e., schizophrenia and bipolar disorder. Multiple mechanisms seem to underlie this association, such high prevalence cardiovascular other physical morbidities, poor lifestyle choices, accelerated aging, including ‘inflammaging’. They all represent opportunities intervention, but it is still unclear whether current therapeutic approaches can prevent the development Other knowledge gaps include dementia applies patients with a certain condition, or if subgroups are vulnerable than others, types linked specific disorders.

Язык: Английский

Subjective sleep quality in healthy young adults moderates associations of sensitivity to punishment and reward with functional connectivity of regions relevant for insomnia disorder

Sleep Medicine, Год журнала: 2025, Номер unknown, С. 106527 - 106527

Опубликована: Апрель 1, 2025

Язык: Английский