Exploration of Olfaction and ChiPSO in Pediatric Cystic Fibrosis DOI Open Access
Tiana M. Saak, Jeremy P. Tervo,

Ben Moore

и другие.

Journal of Clinical Medicine, Год журнала: 2025, Номер 14(8), С. 2583 - 2583

Опубликована: Апрель 9, 2025

Background/Objectives: Olfactory dysfunction (OD) is a common symptom among people with cystic fibrosis (PwCF) and contributes to environmental safety concerns, nutritional challenges, an overall diminished quality of life. OD perceived progress along the lifespan in PwCF, often due worsening sinonasal disease. Among children (CwCF), poorly characterized as limited resources tolerance contribute challenges psychophysical olfactory evaluation pediatric populations. The Children’s Personal Significance Olfaction (ChiPSO) questionnaire was recently proposed tool assess olfaction importance stimulation children. This pilot study aimed evaluate utility ChiPSO cohort ethnically diverse CwCF. Methods: Individuals aged 7–17 physician-diagnosed CF were asked complete questionnaires, including brief on (bQOD-NS), prior undergoing U-Sniff Identification test. Potential associations between questionnaires performance, pulmonary function, demographic characteristics evaluated using Pearson Spearman correlations, independent-sample t-tests, Wilcoxon rank sum tests, multiple linear regression. Results: score positively correlated total [r(13) = 0.640, p 0.010] its subdomain 0.774, < 0.001], though not food 0.450, 0.093], social 0.343, 0.2], or bQOD-NS [r(11) −0.125, 0.7]. Hispanic ethnicity associated (p 0.041). Conclusions: In this preliminary study, increases function sample CwCF, preferential influence personal information. While these results should be interpreted limitations imposed by nature our size, data highlights early adolescent development that can disrupted setting progressive disease

Язык: Английский

Exploration of Olfaction and ChiPSO in Pediatric Cystic Fibrosis DOI Open Access
Tiana M. Saak, Jeremy P. Tervo,

Ben Moore

и другие.

Journal of Clinical Medicine, Год журнала: 2025, Номер 14(8), С. 2583 - 2583

Опубликована: Апрель 9, 2025

Background/Objectives: Olfactory dysfunction (OD) is a common symptom among people with cystic fibrosis (PwCF) and contributes to environmental safety concerns, nutritional challenges, an overall diminished quality of life. OD perceived progress along the lifespan in PwCF, often due worsening sinonasal disease. Among children (CwCF), poorly characterized as limited resources tolerance contribute challenges psychophysical olfactory evaluation pediatric populations. The Children’s Personal Significance Olfaction (ChiPSO) questionnaire was recently proposed tool assess olfaction importance stimulation children. This pilot study aimed evaluate utility ChiPSO cohort ethnically diverse CwCF. Methods: Individuals aged 7–17 physician-diagnosed CF were asked complete questionnaires, including brief on (bQOD-NS), prior undergoing U-Sniff Identification test. Potential associations between questionnaires performance, pulmonary function, demographic characteristics evaluated using Pearson Spearman correlations, independent-sample t-tests, Wilcoxon rank sum tests, multiple linear regression. Results: score positively correlated total [r(13) = 0.640, p 0.010] its subdomain 0.774, < 0.001], though not food 0.450, 0.093], social 0.343, 0.2], or bQOD-NS [r(11) −0.125, 0.7]. Hispanic ethnicity associated (p 0.041). Conclusions: In this preliminary study, increases function sample CwCF, preferential influence personal information. While these results should be interpreted limitations imposed by nature our size, data highlights early adolescent development that can disrupted setting progressive disease

Язык: Английский

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