Architecturally Mediated Allostasis and Neurosustainability: A Proposed Theoretical Framework for the Impact of the Built Environment on Neurocognitive Health
Brain Sciences,
Год журнала:
2025,
Номер
15(2), С. 201 - 201
Опубликована: Фев. 15, 2025
The
global
rise
in
mental
health-related
disorders
represents
a
significant
health
and
wellbeing
challenge,
imposing
substantial
social
economic
burden
on
individuals,
communities,
healthcare
systems.
According
to
the
World
Health
Organization,
one
four
people
globally
will
be
affected
by
or
neurological
at
some
point
their
lives,
highlighting
concern
that
warrants
carefully
considered
innovative
responses.
While
challenges
arise
from
complex,
multifaceted
factors,
emerging
research
indicates
built
environment-the
architecture
of
our
homes,
workplaces,
public
spaces-may
exert
critical
but
underappreciated
influence
outcomes.
This
paper
outlines
novel
theoretical
framework
for
how
visual
stressors
environment
might
trigger
neurophysiological
stress
responses
via
HPA
SAM
axes,
potentially
contributing
over
time
allostatic
load.
In
this
paper,
it
is
proposed
chronic
physiological
strain
can
alter
neuroplastic
processes
neurogenesis
key
brain
regions-such
as
hippocampus,
prefrontal
cortex
(PFC),
anterior
cingulate
(ACC),
amygdala-thereby
affecting
cognitive
health,
emotional
regulation,
overall
wellbeing.
Drawing
principle
neurosustainability,
suggests
long-term
exposure
stress-inducing
environments
may
create
feedback
loops,
particularly
involving
amygdala,
have
downstream
effects
other
areas
linked
adverse
outcomes
such
depression.
By
presenting
framework,
aims
inspire
further
inquiry
applied
experimental
into
intersection
neurophysiology,
environment,
with
particular
emphasis
rigorous
testing
validation
mechanisms,
then
translated
practical
architectural
design
strategies
supporting
doing
so,
hoped
work
contribute
more
holistic
approach
improving
integrates
creation
nurturing,
resilient
spaces
broader
agenda.
Язык: Английский
The Impact of Walking on BDNF as a Biomarker of Neuroplasticity: A Systematic Review
Brain Sciences,
Год журнала:
2025,
Номер
15(3), С. 254 - 254
Опубликована: Фев. 27, 2025
Background/Objectives:
The
brain-derived
neurotrophic
factor
(BDNF)
is
a
critical
exercise-induced
modulator
of
various
neuroplasticity
processes,
including
adult
hippocampal
neurogenesis.
Environmental
affordance
for
physical
activity
novel
theory
that
aims
to
increase
the
BDNF
through
walking
or
climbing
stairs,
stimulated
by
urban
and
interior
environment.
In
systematic
review,
this
paper
explores
association
between
walking,
as
structured
free-living
form
activity,
changes
in
humans
with
healthy
locomotion.
Method:
A
review
registered
protocol,
INPLASY2024110093,
following
PRISMA
guidelines,
includes
English-language
original
research
articles
on
older
human
subjects
who
are
locomotor-healthy,
studies
exercise
presented
non-combined
intervention,
must
report
dependent
variable.
search
was
conducted
using
three
databases:
PubMed,
Web
Science,
Scopus,
resulting
21
eligible
studies.
Results:
This
finds
impact
evidenced,
but
subject
moderate
high
intensities
single
bouts.
At
same
time,
long-term
effects
yet
be
fully
understood,
potentially
due
uptake
functional
brain
improvements,
muscle
repair,
instead
an
accumulation
itself,
still
confirm
important
role
neurosustainability.
Age
environmental
factors
such
heat
also
found
affect
BDNF.
narrative
synthesis
provides
elaborate
explanations
understanding
those
complex
dynamics
before
reaching
future
conclusions
concentrations.
Conclusions:
highlights
potential
played
moderate-
high-intensity
lifestyle
intervention
can
utilised
built
environment
promote
adaptive
changes,
sustainable
regulation
Язык: Английский