Amplification of the therapeutic potential of AMPA receptor potentiators from the nootropic era to today

Pharmacology Biochemistry and Behavior, Год журнала: 2025, Номер 248, С. 173967 - 173967

Опубликована: Янв. 31, 2025

Язык: Английский

---

Integrated Advancements in Neuroplasticity, Psychedelic Therapeutics, and AI-Driven Innovations for Precision Medicine

ACS Medicinal Chemistry Letters, Год журнала: 2025, Номер 16(4), С. 520 - 522

Опубликована: Март 6, 2025

Recent advancements in psychedelic therapeutics, tryptamine derivatives, neuroplastic modulators, and AI-powered machine-learning platforms mark a new frontier precision medicine. These innovations address critical challenges neurological psychiatric disorders, chronic pain management, computational accessibility. By harnessing the principles of receptor modulation, targeted delivery systems, simplified AI integration, these breakthroughs promise transformative solutions for patient care technological development.

Язык: Английский

---

Innovative Approaches in Psychedelics, AI, and Communication: A Multi-Domain Perspective

ACS Medicinal Chemistry Letters, Год журнала: 2025, Номер 16(4), С. 514 - 516

Опубликована: Март 11, 2025

Emerging innovations across psychedelics, artificial intelligence (AI), and communication technologies are reshaping healthcare beyond. This Patent Highlight showcases advancement in sublingual delivery systems for asymmetric phenylethylamine compounds, AI-assisted positioning, multi-modal data fusion, respectively. These inventions address challenges like drug inefficiencies, mental health treatment gaps, precision communication, integrated diagnostics. Together, they demonstrate the transformative potential of cross-disciplinary technological advancements enhancing precision, accessibility, scalability their respective fields.

Язык: Английский

---

Unveiling Reality: Psychedelics, Neural Filtering, and the Future of Psychiatric Medicine

ACS Medicinal Chemistry Letters, Год журнала: 2025, Номер 16(4), С. 500 - 503

Опубликована: Март 19, 2025

Psychedelics and AI modulate cognitive frameworks, disrupt rigid thought patterns, enhance neuroplasticity, offering therapeutic potential for depression, PTSD, addiction. Relaxing neural filters reveal altered states of consciousness, challenging perceptions reality. This Viewpoint explores their neurobiological mechanisms AI's role in augmenting psychiatric treatments.

Язык: Английский

---

Targeting Phantom Pain with Psilocybin: Toward Integration with Adaptive Sensory Technologies

ACS Medicinal Chemistry Letters, Год журнала: 2025, Номер unknown

Опубликована: Апрель 10, 2025

Psilocybin demonstrates a clinically meaningful reduction in phantom and residual limb pain. Adaptive sensory environments (ASEs) separately offer biosensor-guided modulation of psychological states during psychoactive therapy. This Patent Highlight explores the pharmacological findings psilocybin trial discusses future integration with ASE systems to precision scale psychedelic-assisted interventions.

Язык: Английский

---

Novel Phenylalkylamines as 5-HT2A Agonists for Treating Psychiatric Disorders

ACS Medicinal Chemistry Letters, Год журнала: 2025, Номер unknown

Опубликована: Май 14, 2025

Язык: Английский

---

Novel Substituted Lactams as 5-HT1A Agonists for Treating Neuropsychiatric Diseases

ACS Medicinal Chemistry Letters, Год журнала: 2025, Номер unknown

Опубликована: Май 16, 2025

Язык: Английский

---

Novel Ergolines as 5-HT2A Agonists for Treating Mood Disorders

ACS Medicinal Chemistry Letters, Год журнала: 2025, Номер unknown

Опубликована: Май 21, 2025

Язык: Английский

---

Novel Desamide Isotryptamine Tetracycles as 5-HT2C Agonists for Treating Brain Disorders

ACS Medicinal Chemistry Letters, Год журнала: 2025, Номер unknown

Опубликована: Май 21, 2025

Язык: Английский

---

Novel Indole Derivatives as Serotonergic Psychedelic Agents for Treating Psychosis, Mental Illness, and CNS Disorders

ACS Medicinal Chemistry Letters, Год журнала: 2025, Номер unknown

Опубликована: Май 29, 2025

Язык: Английский

---