THE ROLE OF CONTINUOUS MONITORING IN ONCOLOGY PATIENTS RECEIVING RADIOTHERAPY OR CHEMOTHERAPY. REVIEW

BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY, Год журнала: 2025, Номер unknown, С. 88 - 98

Опубликована: Янв. 10, 2025

Background: Oral cancer is a major public health problem worldwide and the prevention of oral its associated morbidity mortality depends on early detection. Delayed diagnosis contributor to dismal survival rate over five years.Currently, various monitoring methods have been actively used for purpose active detection asymptomatic cancer. This study provides an overview main concepts principles organizing continuous in oncology patients receiving radiotherapy or chemotherapy. Methods: review was reported per PRISMA guidelines conducted publications covering scientific research diagnostics, management protocols, radiotherapy, chemotherapy malignant neoplasms Medline, Scopus, Web science, PubMed (search 162 which finally included 75 articles). Two authors screened results searches against inclusion criteria, extracted data assessed risk bias independently duplicate. Results: To prevent minimize complications, appropriate protocol needed should include assessment prior treatment. Early recognition can improve patient reduce morbidity. Conclusion: Continuous with primary care settings radiation therapy may complications effectiveness combination therapy. cavity, it very important pre-treat existing diseases, this aspect, cooperation dentist oncologist as one team important. will help dental practitioners manage risks potential requiring

Язык: Английский

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Unveiling the Therapeutic Potential of Soft Plasma Jet and Nitric-Oxide Enriched Plasma-Activated Water (NO-PAW) on Oral Cancer YD-10B Cells: A Comprehensive Investigation of Direct and Indirect Treatments

Plasma Chemistry and Plasma Processing, Год журнала: 2025, Номер unknown

Опубликована: Фев. 19, 2025

Язык: Английский

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Oral Health-Related Quality of Life Outcomes Associated with Oral Squamous Cell Carcinoma Among Patients in Ahvaz City, Iran

Jundishapur Journal of Chronic Disease Care, Год журнала: 2025, Номер 14(1)

Опубликована: Янв. 21, 2025

Background: Patients with oral cancer often face significant side effects from both the disease and its treatments, such as tooth loss, speech difficulties, changes in physical appearance. These challenges can profoundly affect their self-esteem. Objectives: To gain a deeper understanding of health-related quality life (OHRQOL) this population, study examines OHRQOL individuals squamous cell carcinoma mouth Khuzestan province. Methods: This cross-sectional focused on patients (OSCC) registered province registry system 2023. Sampling was conducted using census method. Participants were included if they had confirmed diagnosis OSCC consented to participate. Those who withdrew or provided incomplete questionnaires excluded. Data collected Oral Health Impact Profile-14 (OHIP-14) Questionnaire, administered by researcher, allowing participants select responses that best reflected experiences. Statistical analysis SPSS 27 (IBM Statistics, Armonk, NY, USA). Results: A total patients, 47 males 32 females, analysis. The findings current indicated mean score 6.15 ± 31.45, which is at moderate level. highest for dimensions attributed disability, while psychological disability lowest. Although study, no relationship observed between any variables OHRQOL, correlation found functional limitations marital status, decayed teeth, dental restoration, income (P < 0.05). Moreover, education, job, insurance types Additionally, handicap significantly higher among single compared married Conclusions: improve health OSCC, public initiatives should emphasize preventive interventions.

Язык: Английский

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Effect of 70 Gy tumor therapeutic radiation applied intermittently or directly on microcosm biofilm composition and dental hard tissues and its potential to cause dental caries.

Journal of Dentistry, Год журнала: 2025, Номер unknown, С. 105678 - 105678

Опубликована: Март 1, 2025

Язык: Английский

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Oral Mucositis and Pain in Hypofractionated Head and Neck Radiotherapy Protocols

Special Care in Dentistry, Год журнала: 2025, Номер 45(2)

Опубликована: Март 1, 2025

Язык: Английский

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ONCOllab for Transmission of Knowledge Related to Oral Complications of Cancer Therapy Among Dental Students

European Journal Of Dental Education, Год журнала: 2025, Номер unknown

Опубликована: Март 14, 2025

ABSTRACT Introduction ONCOllab is a social media application developed by FDI to improve the management of oral complications that may arise during cancer therapy. This study aimed evaluate effects on learning and perception among dental students. Material Method A theoretical test therapy determine baseline level knowledge was given fourth‐year Students were randomly divided into two groups. All students attended lecture‐based education After lecture, randomised Group 1 (no further education) or 2 (presentation about with subsequent utilisation). One week later, second applied assess levels. The students' overall satisfaction levels in also evaluated. Results included 59 participants [female, 35 (59%)]. results first evaluation found similar between groups ( p > 0.05). test's significantly higher both < However, group (Group 2) showed than for scores = 0.001). beneficial reported they would like use it post‐graduation period. Conclusion Both ONCOllab‐supported approaches improved addition educational superiority, be associated satisfactory terms student perception.

Язык: Английский

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Prosthetic rehabilitation of patients with maxillary oncology defects using zygomatic implants

International Journal of Implant Dentistry, Год журнала: 2024, Номер 10(1)

Опубликована: Июнь 10, 2024

Abstract Purpose Prosthetics for patients after oncological resection of the upper jaw is a complex problem associated with physiological and anatomical separation oral cavity nasal/paranasal region. This study reports clinical results use zygomatic implants prosthetic rehabilitation in maxillectomy due to tumors. Materials methods The included 16 who underwent using implant period from 2021 2023. After tumor was removed, immediate surgical obturators were placed. Main performed 6–12 months removal, but before that, temporary obturator made used. Six-twelve resection, 1–4 inserted into bone unilaterally or bilaterally. A total 42 installed, 2 which unsuccessful removed 1 patient. placed guide, planned prepared digitally. Results No postsurgical complications seen, discharged hospital 7–10 days. able return normal diet (hard food) just 7 days following surgery, no further complaints regarding function pain, apart residual edema caused by intervention. Conclusions prostheses fixed on maxillary defects an effective method prosthodontic cases maxillectomy.

Язык: Английский

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Synthesis and Evaluation of amyloid beta peptide/ Ruthenium III -based complex drugs as drug delivery and anticancer activity

Toxicology Reports, Год журнала: 2024, Номер 13, С. 101778 - 101778

Опубликована: Окт. 18, 2024

The development and characterization of anticancer complex drugs (ACD), specifically Amyloid Beta Peptide (ABP) - Ruthenium III (Ru III) nivolumab (NB), were explored through analytical techniques. Fourier-transform infrared (FTIR) spectroscopy demonstrated the structural transformation peptides from α-helical to β-sheet formations, aligning with amyloid fibril aggregation. (III) synthesis was confirmed distinct absorption peaks in FTIR analysis. High-resolution scanning electron microscopy (HRSEM) revealed fibrous smooth morphology ACD, while thermogravimetric analysis (TGA) decomposition stages stability ruthenium complexes. encapsulation efficiency vitro release profile (NB) within ABP-RuIII-NB investigated, showing a two-phase over 40 h. Cytotoxicity studies using acridine orange ethidium bromide staining techniques indicated significant apoptosis human oral squamous cell carcinoma (OSCC) -treated cells. These findings highlight potential as an effective cancer treatment controlled drug high cytotoxicity against

Язык: Английский

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Dental Care for Cancer Patients in the Prevention of Complications of Chemotherapy and Head and Neck Radiation Therapy

Journal of Tumor Science Research, Год журнала: 2024, Номер unknown, С. 1 - 4

Опубликована: Фев. 26, 2024

Oncological diseases occupy one of the first places in structure disability and mortality population. The main methods treating patients with malignant tumors maxillofacial area are surgical method, radiation therapy chemotherapy. Treatment only listed It is rarely performed, mainly at stage cancer situ or I disease. treatment depends on clinical morphological characteristics tumor requires use all simultaneously a certain sequence. Radiation chemotherapy treatments not have systemic side effects, but also effects area. Against background antitumor treatment, there an exacerbation concomitant chronic diseases, including odontogenic ones. Pathological changes appear mucous membrane oral cavity, skin, subcutaneous tissue, salivary glands bone marrow jaw bones. degree damage to these structures during their initial condition. At same time, condition cavity affects quality treatment. Poor hygiene lesions can cause development episodic fevers other general complications. All this stopping tactics which reduces its radicalism. becomes obvious that sanitation carried out before by oncologist, will avoid reduce frequency complications area, improve life oncology patient. Dental care for such patient has features individual approach. purpose study was review literature tissue arising from head neck region. In Google Scholar, Medline, Scopus, Web Sciences, PubMed systematic conducted. Search keywords terms included cancer, dental care, prevention manifestationin, chemotherapy, therapy. Conducted preliminary search reviewed 132 titles abstracts literary 48 article. This article analyzes tissues resulting provides practical recommendations management category patients.

Язык: Английский

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Prevention and Care of Oral Manifestations in Cancer Patients Receiving Chemotherapy and Head and Neck Radiation Therapy. Systematic Review

JSM Head and Neck Cancer Cases and Reviews, Год журнала: 2024, Номер 4(1), С. 1 - 5

Опубликована: Янв. 10, 2024

Purpose: The purpose of this systematic review was to evaluate current evidence prevent and care oral manifestations chemotherapy head neck radiation therapy. Methods: Study selected if they met the following criteria: design - random allocation participants; participants anyone with cancer receiving or radiotherapy treatment for cancer; interventions agents prescribed complication. Search keywords terms included cancer, dental care, prevention complications tissue lesions manifestationin, chemotherapy, therapy, length hospitalisation, cost patient quality life. Results: Conducted a preliminary search reviewed 132 titles abstracts in 48 full-text articles were high methodological quality. This analyzes main tissues resulting from therapy area provides practical recommendations management category patients. methods treating patients malignant tumors maxillofacial are surgical method, chemotherapy. depends on clinical morphological characteristics tumor requires use all simultaneously certain sequence. Radiation treatments not only have systemic side effects, but also effects area. Against background antitumor treatment, there is an exacerbation concomitant chronic diseases, including odontogenic ones. Pathological changes appear mucous membrane cavity, skin, subcutaneous tissue, salivary glands bone marrow jaw bones. Poor hygiene can cause development episodic fevers other general complications. All stopping tactics which reduces its radicalism. Conclusion: demonstrated that regular extensive health education, sanitation carried out before by oncologist, will avoid reduce frequency area, improve life oncology patient. Dental such has features individual approach.

Язык: Английский

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