SARS CoV-2 in tumor tissue in glioblastoma patients – preliminary study DOI Creative Commons

Michał Brzozowski,

Marcin Koleśnik, Aleksander Michalski

и другие.

Current Issues in Pharmacy and Medical Sciences, Год журнала: 2024, Номер 37(4), С. 216 - 220

Опубликована: Ноя. 28, 2024

Abstract SARS-CoV-2 infection often causes neurological disorders. Experimental studies on an animal model have shown that is able to cross the blood-brain barrier. Researchers also discovered can infect glial cells. Gliomas are most common type of brain tumor. Oncological patients at high risk infections, including SARS-CoV-2. Moreover, their weakened immunity level antibodies after or vaccination be lower than in healthy population. Therefore, aim our study was evaluate occurrence RNA tumor tissue collected during surgery. We tested anti-SARS-CoV-2 these patients. The obtained results indicate tropism virus – glioblastoma. anti-SARS higher with detected tumour tissue.

Язык: Английский

Artificial Intelligence for Neuroimaging in Pediatric Cancer DOI Open Access
Josué Luiz Dalboni da Rocha, Jesyin Lai, Pankaj Pandey

и другие.

Cancers, Год журнала: 2025, Номер 17(4), С. 622 - 622

Опубликована: Фев. 12, 2025

Background/Objectives: Artificial intelligence (AI) is transforming neuroimaging by enhancing diagnostic precision and treatment planning. However, its applications in pediatric cancer remain limited. This review assesses the current state, potential applications, challenges of AI for cancer, emphasizing unique needs population. Methods: A comprehensive literature was conducted, focusing on AI’s impact through accelerated image acquisition, reduced radiation, improved tumor detection. Key methods include convolutional neural networks segmentation, radiomics characterization, several tools functional imaging. Challenges such as limited datasets, developmental variability, ethical concerns, need explainable models were analyzed. Results: has shown significant to improve imaging quality, reduce scan times, enhance accuracy neuroimaging, resulting segmentation outcome prediction treatment. progress hindered scarcity issues with data sharing, implications applying vulnerable populations. Conclusions: To overcome limitations, future research should focus building robust fostering multi-institutional collaborations developing interpretable that align clinical practice standards. These efforts are essential harnessing full improving outcomes children cancer.

Язык: Английский

Процитировано

2

Multi-Modality Fusion and Tumor Sub-Component Relationship Ensemble Network for Brain Tumor Segmentation DOI Creative Commons
Jinyan Zhou, Shuwen Wang, Hao Wang

и другие.

Bioengineering, Год журнала: 2025, Номер 12(2), С. 159 - 159

Опубликована: Фев. 6, 2025

Deep learning technology has been widely used in brain tumor segmentation with multi-modality magnetic resonance imaging, helping doctors achieve faster and more accurate diagnoses. Previous studies have demonstrated that the weighted fusion method effectively extracts modality importance, laying a solid foundation for imaging segmentation. However, challenge of fusing features single-modality remains unresolved, which motivated us to explore an effective solution. We propose feature recalibration network Specifically, we designed dual module achieves calibration by integrating complementary specific single modality. Experimental results on BraTS 2018 dataset showed proposed outperformed existing multi-modal methods across multiple evaluation metrics, spatial significantly improving results, including Dice score increases 1.7%, 0.5%, 1.6% enhanced core, whole tumor, core regions, respectively.

Язык: Английский

Процитировано

0

SARS CoV-2 in tumor tissue in glioblastoma patients – preliminary study DOI Creative Commons

Michał Brzozowski,

Marcin Koleśnik, Aleksander Michalski

и другие.

Current Issues in Pharmacy and Medical Sciences, Год журнала: 2024, Номер 37(4), С. 216 - 220

Опубликована: Ноя. 28, 2024

Abstract SARS-CoV-2 infection often causes neurological disorders. Experimental studies on an animal model have shown that is able to cross the blood-brain barrier. Researchers also discovered can infect glial cells. Gliomas are most common type of brain tumor. Oncological patients at high risk infections, including SARS-CoV-2. Moreover, their weakened immunity level antibodies after or vaccination be lower than in healthy population. Therefore, aim our study was evaluate occurrence RNA tumor tissue collected during surgery. We tested anti-SARS-CoV-2 these patients. The obtained results indicate tropism virus – glioblastoma. anti-SARS higher with detected tumour tissue.

Язык: Английский

Процитировано

0