A COMPLETE SOJOURN ON NANOTECHNOLOGICAL ADVANCEMENTS AND NANOCARRIERS APPLICATIONS IN ARTHRITIS MANAGEMENT

Journal of Drug Delivery Science and Technology, Год журнала: 2025, Номер unknown, С. 106705 - 106705

Опубликована: Фев. 1, 2025

Язык: Английский

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Advances in Materials Science for Precision Melanoma Therapy: Nanotechnology-Enhanced Drug Delivery Systems

Pharmaceutics, Год журнала: 2025, Номер 17(3), С. 296 - 296

Опубликована: Фев. 24, 2025

Melanoma, a highly aggressive form of skin cancer, poses major therapeutic challenge due to its metastatic potential, resistance conventional therapies, and the complexity tumor microenvironment (TME). Materials science nanotechnology advances have led using nanocarriers such as liposomes, dendrimers, polymeric nanoparticles, metallic nanoparticles transformative solutions for precision melanoma therapy. This review summarizes findings from Web Science, PubMed, EMBASE, Scopus, Google Scholar highlights role in overcoming treatment barriers. Nanoparticles facilitate passive active targeting through mechanisms enhanced permeability retention (EPR) effect functionalization with tumor-specific ligands, thereby improving accuracy drug delivery reducing systemic toxicity. Stimuli-responsive systems multi-stage further improve overcome challenges poor penetration resistance. Emerging platforms combine diagnostic imaging delivery, paving way personalized medicine. However, there are still issues scalability, biocompatibility, regulatory compliance. comprehensive potential integrating genetics proteomics, scalable, patient-specific therapies. These interdisciplinary innovations promise redefine provide safer, more effective, accessible treatments. Continued research is essential bridge gap between evidence-based scientific clinical applications.

Язык: Английский

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Nanoparticle Delivery Systems for Skin-Localized Chemotherapy in Non-Melanoma Skin Cancers

Open Journal of Regenerative Medicine, Год журнала: 2025, Номер 14(01), С. 1 - 18

Опубликована: Янв. 1, 2025

Язык: Английский

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Recent advances in polymeric and lipid stimuli-responsive nanocarriers for cell-based cancer immunotherapy

Nanomedicine, Год журнала: 2024, Номер unknown, С. 1 - 24

Опубликована: Ноя. 14, 2024

Conventional cancer therapy has major limitations, including non-specificity, unavoidable side effects, low specific tumor accumulation and systemic toxicity. In recent years, more effective precise treatment methods have been developed, cell-based immunotherapy. Carriers that can accurately specifically target cells equip them to combat are particularly important for developing this therapy. As a result, attention drawn smart nanocarriers react stimuli. Thus, stimuli-responsive attracted increasing because they change their physicochemical properties in response stimulus conditions, such as pH, enzymes, redox agents, hypoxia, light temperature. This review highlights advances various nanocarriers, discussing loading, targeted delivery, cellular uptake, biocompatibility immunomodulation Finally, future challenges perspectives regarding the possible clinical translation of discussed.

Язык: Английский

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Embracing the future: The application of regenerative biomaterials in the spinal disorders

Biomedical Technology, Год журнала: 2024, Номер 9, С. 100068 - 100068

Опубликована: Дек. 25, 2024

Язык: Английский

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