Development of potent and selective tetrahydro-β-carboline-based HDAC6 inhibitors with promising activity against triple-negative breast cancer DOI

Aya Ahmed Fathy,

A. M. M. A. Allam, Ahmed K. ElHady

и другие.

RSC Medicinal Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Overexpression of histone deacetylase 6 (HDAC6) is implicated in tumorigenesis, invasion, migration, survival, apoptosis, and growth various malignancies, making it a promising target for cancer treatment.

Язык: Английский

Unlocking the potential of novel Tetrahydro-β-Carboline-based HDAC6 inhibitors for colorectal Cancer therapy: Design, synthesis and biological evaluation DOI

Noreen Hemida,

Dalia S. El‐Gamil, Ahmed K. ElHady

и другие.

Bioorganic Chemistry, Год журнала: 2025, Номер unknown, С. 108454 - 108454

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0
Development of potent and selective tetrahydro-β-carboline-based HDAC6 inhibitors with promising activity against triple-negative breast cancer DOI

Aya Ahmed Fathy,

A. M. M. A. Allam, Ahmed K. ElHady

и другие.

RSC Medicinal Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Overexpression of histone deacetylase 6 (HDAC6) is implicated in tumorigenesis, invasion, migration, survival, apoptosis, and growth various malignancies, making it a promising target for cancer treatment.

Язык: Английский

Процитировано

0