Comprehensive Analysis of Predictors and Outcomes in Breast Cancer Screening in Romania: Insights from Demographic, Clinical, and Lifestyle Factors DOI Open Access

Oana Maria Burciu,

Ioan Sas,

Adrian-Grigore Merce

и другие.

Journal of Clinical Medicine, Год журнала: 2025, Номер 14(5), С. 1415 - 1415

Опубликована: Фев. 20, 2025

Background/Objectives: The primary purpose of this study is to provide a more in-depth insight into various demographic, clinical, and lifestyle factors in relation breast cancer predict the extent which certain variables described as “predictors” might lead further investigation. By analyzing large cohort, we are able valuable up-to-date information on screening, support specialists, enhance international screening guidelines. Methods: We screened for population women aged 50 69 years by using standardized imaging method (breast mammography) ultrasonography complementary imagistic tool, compared results with gold standard, biopsy. For this, 58,760 no known history coming from 4 major regions Romania (North-East, North-West, South-East, West) were first evaluated through mammography. Out these, 3197 positive mammograms subsequently underwent ultrasound examination. remaining 688 patients referred Results: statistical analysis revealed several predictors such body mass index (BMI), family medical cancer, age at birth, menopause that influenced progression mammography (first stage program) towards echography (additional modality). Furthermore, established age, BMI significant biopsy (the last program). number biopsies (688) out total (58,760), calculated detection rate 8 per 1000 patients. Lastly, studying patient demographics context (BC) observed participants an urban environment presented higher mammographic ones rural provenience. Conclusions: Our analyzed cohort offers real world data shows multiple positively associated increased risk BC. Older older menopausal all estrogen-dependent linked our study. findings concerning rural/urban disparities regional differences highlight need region-specific interventions address factors, improve healthcare access, follow-up protocols, particularly underserved areas like North-East South-East regions.

Язык: Английский

Comprehensive Analysis of Predictors and Outcomes in Breast Cancer Screening in Romania: Insights from Demographic, Clinical, and Lifestyle Factors DOI Open Access

Oana Maria Burciu,

Ioan Sas,

Adrian-Grigore Merce

и другие.

Journal of Clinical Medicine, Год журнала: 2025, Номер 14(5), С. 1415 - 1415

Опубликована: Фев. 20, 2025

Background/Objectives: The primary purpose of this study is to provide a more in-depth insight into various demographic, clinical, and lifestyle factors in relation breast cancer predict the extent which certain variables described as “predictors” might lead further investigation. By analyzing large cohort, we are able valuable up-to-date information on screening, support specialists, enhance international screening guidelines. Methods: We screened for population women aged 50 69 years by using standardized imaging method (breast mammography) ultrasonography complementary imagistic tool, compared results with gold standard, biopsy. For this, 58,760 no known history coming from 4 major regions Romania (North-East, North-West, South-East, West) were first evaluated through mammography. Out these, 3197 positive mammograms subsequently underwent ultrasound examination. remaining 688 patients referred Results: statistical analysis revealed several predictors such body mass index (BMI), family medical cancer, age at birth, menopause that influenced progression mammography (first stage program) towards echography (additional modality). Furthermore, established age, BMI significant biopsy (the last program). number biopsies (688) out total (58,760), calculated detection rate 8 per 1000 patients. Lastly, studying patient demographics context (BC) observed participants an urban environment presented higher mammographic ones rural provenience. Conclusions: Our analyzed cohort offers real world data shows multiple positively associated increased risk BC. Older older menopausal all estrogen-dependent linked our study. findings concerning rural/urban disparities regional differences highlight need region-specific interventions address factors, improve healthcare access, follow-up protocols, particularly underserved areas like North-East South-East regions.

Язык: Английский

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