Clinical Outcomes of Intensity Modulated Proton Therapy for Salivary Gland Carcinoma: High Local Control and Quality of Life Preservation DOI Creative Commons

Gaku Takano,

Daisuke Kawakita, Hiromitsu Iwata

и другие.

Head & Neck, Год журнала: 2025, Номер unknown

Опубликована: Март 31, 2025

ABSTRACT Background In recent years, particle therapy has shown promise as a local treatment for salivary gland carcinoma (SGC); however, its efficacy and safety remain unclear. This study aimed to evaluate the clinical outcomes of intensity‐modulated proton (IMPT) SGC. Methods We performed single‐institution retrospective analysis patients with SGC who underwent IMPT. Results IMPT was on 28 patients, which 18 were definitive 10 postoperative treatment. The 2‐year overall survival (OS), progression‐free (PFS), control (LC) rates cases 70.1%, 25.0%, 82.5%, respectively. OS, PFS, LC 100%, 80.0%, 90.0%, Quality life scores in EORTC QLQ‐C30 QLQ‐HN35 preserved 1 year after Conclusions Our suggests patients.

Язык: Английский

Clinical Outcomes of Intensity Modulated Proton Therapy for Salivary Gland Carcinoma: High Local Control and Quality of Life Preservation DOI Creative Commons

Gaku Takano,

Daisuke Kawakita, Hiromitsu Iwata

и другие.

Head & Neck, Год журнала: 2025, Номер unknown

Опубликована: Март 31, 2025

ABSTRACT Background In recent years, particle therapy has shown promise as a local treatment for salivary gland carcinoma (SGC); however, its efficacy and safety remain unclear. This study aimed to evaluate the clinical outcomes of intensity‐modulated proton (IMPT) SGC. Methods We performed single‐institution retrospective analysis patients with SGC who underwent IMPT. Results IMPT was on 28 patients, which 18 were definitive 10 postoperative treatment. The 2‐year overall survival (OS), progression‐free (PFS), control (LC) rates cases 70.1%, 25.0%, 82.5%, respectively. OS, PFS, LC 100%, 80.0%, 90.0%, Quality life scores in EORTC QLQ‐C30 QLQ‐HN35 preserved 1 year after Conclusions Our suggests patients.

Язык: Английский

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