Metal-Free Catalytic Synthesis of Tetrasubstituted Furans from α-Hydroxy Ketones and Cyano Compounds DOI Creative Commons

Yu Zeng,

Shi-Hang Yang,

Ji-Lin Guo

и другие.

Molecules, Год журнала: 2025, Номер 30(8), С. 1832 - 1832

Опубликована: Апрель 19, 2025

A novel method for the efficient and straightforward synthesis of tetrasubstituted furans is presented, employing a base-catalyzed reaction α-hydroxy ketones cyano compounds. The proceeds under relatively mild conditions, utilizes readily available starting materials, exhibits good functional group tolerance high yields. Notably, this obviates need expensive metal catalysts introduces crucial groups such as amino moieties. Furthermore, it avoids prerequisite functionalization substrates, thereby enhancing atomic economy.

Язык: Английский

Metal-Free Catalytic Synthesis of Tetrasubstituted Furans from α-Hydroxy Ketones and Cyano Compounds DOI Creative Commons

Yu Zeng,

Shi-Hang Yang,

Ji-Lin Guo

и другие.

Molecules, Год журнала: 2025, Номер 30(8), С. 1832 - 1832

Опубликована: Апрель 19, 2025

A novel method for the efficient and straightforward synthesis of tetrasubstituted furans is presented, employing a base-catalyzed reaction α-hydroxy ketones cyano compounds. The proceeds under relatively mild conditions, utilizes readily available starting materials, exhibits good functional group tolerance high yields. Notably, this obviates need expensive metal catalysts introduces crucial groups such as amino moieties. Furthermore, it avoids prerequisite functionalization substrates, thereby enhancing atomic economy.

Язык: Английский

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