Leveraging Administrative Health Databases to Address Health Challenges in Farming Populations: Scoping Review and Bibliometric Analysis (1975-2024)

JMIR Public Health and Surveillance, Год журнала: 2025, Номер 11, С. e62939 - e62939

Опубликована: Янв. 9, 2025

Background Although agricultural health has gained importance, to date, much of the existing research relies on traditional epidemiological approaches that often face limitations related sample size, geographic scope, temporal coverage, and range events examined. To address these challenges, a complementary approach involves leveraging reusing data beyond its original purpose. Administrative databases (AHDs) are increasingly reused in population-based digital public health, especially for populations such as farmers, who distinct environmental risks. Objective We aimed explore reuse AHDs addressing issues within farming by summarizing current landscape AHD-based identifying key areas interest, gaps, unmet needs. Methods conducted scoping review bibliometric analysis using PubMed Web Science. Building upon previous reviews research, we comprehensive literature search 72 terms population AHDs. identify hot spots, directions, used keyword frequency, co-occurrence, thematic mapping. also explored profile exposome mapping co-occurrences between factors outcomes. Results Between 1975 April 2024, 296 publications across 118 journals, predominantly from high-income countries, were identified. Nearly one-third associated with well-established cohorts, Agriculture Cancer Agricultural Health Study. The most frequently included disease registers (158/296, 53.4%), electronic records (124/296, 41.9%), insurance claims (106/296, 35.8%), (95/296, 32.1%), hospital discharge (41/296, 13.9%). Fifty (16.9%) studies involved >1 million participants. broad exposure proxies used, (254/296, 85.8%) relied proxies, which failed capture specifics tasks. Research remains underexplored, predominant focus specific external exposome, particularly pesticide exposure. A limited have been examined, primarily cancer, mortality, injuries. Conclusions increasing use holds major potential advance populations. However, substantial gaps persist, low-income regions among underrepresented subgroups, women, children, contingent workers. Emerging issues, including per- polyfluoroalkyl substances, biological agents, microbiome, microplastics, climate change, warrant further research. Major persist understanding various conditions, cardiovascular, reproductive, ocular, sleep-related, age-related, autoimmune diseases. Addressing overlooked is essential comprehending risks faced communities guiding policies. Within this context, promoting conjunction other sources (eg, mobile social data, wearables) artificial intelligence approaches, represents promising avenue future exploration.

Язык: Английский

Investigating Parkinson’s disease risk across farming activities using data mining and large-scale administrative health data

npj Parkinson s Disease, Год журнала: 2025, Номер 11(1)

Опубликована: Янв. 8, 2025

Abstract The risk of Parkinson’s disease (PD) associated with farming has received considerable attention, in particular for pesticide exposure. However, data on PD specific activities is lacking. We aimed to explore whether exhibited a higher than others among the entire French farm manager (FM) population. A secondary analysis real-world administrative insurance claim and electronic health/medical records (TRACTOR project) was conducted estimate 26 using mining. cases were identified through chronic declarations antiparkinsonian drug claims. There 8845 1,088,561 FMs. highest-risk group included FMs engaged pig farming, cattle truck fruit arboriculture, crop mean hazard ratios (HRs) ranging from 1.22 1.67. lowest-risk all involving horses small animals, as well gardening, landscaping reforestation companies (mean HRs: 0.48–0.81). Our findings represent preliminary work that suggests potential involvement occupational factors related onset development. Future research focusing farmers high-risk will allow uncover by better characterizing exposome, which could improve surveillance farmers.

Язык: Английский

Gut microbiota and microRNAs as biomarkers in Parkinson’s disease: early identification, diagnostic and potential treatments

Molecular and Cellular Biochemistry, Год журнала: 2025, Номер unknown

Опубликована: Март 31, 2025

Язык: Английский