Frontiers in Bioengineering and Biotechnology, Год журнала: 2025, Номер 13

Опубликована: Март 28, 2025

Reproductive engineering encompasses a range of advanced tissue techniques aimed at addressing infertility that is non-curable with current assisted reproductive technology (ART). The use animal models has been crucial for these advancements, notable preference non-human primates (NHPs) given their genetic, anatomical, and physiological similarities to humans. Therefore, NHPs are invaluable studying engineering. Thus, in studies, bridge the anatomical gaps between rodent Their shared features humans, such as menstrual cycles, placentation, hormonal regulation, allow more accurate modeling physiology pathology. These traits make indispensable exploration engineering, including treatments, genetic uterine transplantation. transformative field addresses enhances health. By leveraging unique NHPs, researchers can deepen understanding processes refine ART human use. Advances have enabled creation transgenic NHP models, which used modify genes investigate roles various purposes, process, mentioned earlier, closely related technique, fertility, embryogenesis, pregnancy. relation studies necessity model prerequisites critically integrating ethical practices exploring complementary methodologies. This review overviews types frequently using may suggest broader way

Язык: Английский