The FRET‐Based APTA Sensor/Cy3 Complex for Glucose Determination

Luminescence, Год журнала: 2025, Номер 40(2)

Опубликована: Фев. 1, 2025

ABSTRACT This study developed a sensitive and cost‐effective fluorescent probe based on the Förster Resonance Energy Transfer (FRET) method to monitor blood glucose levels. The APTA sensor/Cy3 consisted of cadmium telluride quantum dots modified with thioglycolic acid (CdTe‐TGA QDs), thiol‐glucose‐aptamer, Cy3‐labeled aptamer. Due well‐matched emission spectrum CdTe QDs absorption Cy3, FRET system decreased fluorescence intensity. However, molecules quenched it when introduced system. linear relationship between intensity concentration was established detection limit 7.72 × 10 −9 M. complex demonstrated excellent selectivity specificity toward high recovery rate 96.00–101.11% in human serum urine using spiking method. structural morphological characteristics were confirmed by UV–visible spectroscopy, Fourier‐transform infrared spectroscopy (FT‐IR), X‐ray photoelectron (XPS), field scanning electron microscopy (FESEM), energy dispersive (EDX), transmission (TEM), atomic force (AFM), dynamic light scattering (DLS) analyses. results suggest that FRET‐based would lead development probes for screening biological metabolites clinical diagnostics research.

Язык: Английский

Characterization and Application of the Fluorescent APTA-Nanobiosensors Based on CdTe-TGA QDs for Determination of 25-Hydroxyvitamin D3

BioNanoScience, Год журнала: 2025, Номер 15(2)

Опубликована: Фев. 26, 2025

Язык: Английский

An innovative chalcogenide transfer agent for improved aqueous quantum dot synthesis

Chemical Science, Год журнала: 2024, Номер 15(33), С. 13148 - 13159

Опубликована: Янв. 1, 2024

Development of an innovative chalcogenide transfer vehicle for improving large scale aqueous quantum dot synthesis.

Язык: Английский