Langmuir, Год журнала: 2024, Номер unknown
Опубликована: Дек. 10, 2024
The development of multifunctional films with rapidly killing microorganisms and adsorbing residual antibiotics in wastewater remains a challenging endeavor. In this work, the chitosan/zinc ion/polyoxometalate (CS/Zn
Язык: Английский
International Journal of Biological Macromolecules, Год журнала: 2024, Номер unknown, С. 136840 - 136840
Опубликована: Окт. 1, 2024
Язык: Английский
Процитировано
4
Results in Chemistry, Год журнала: 2025, Номер unknown, С. 102044 - 102044
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Advances in experimental medicine and biology, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Materials Today Bio, Год журнала: 2025, Номер 31, С. 101558 - 101558
Опубликована: Фев. 5, 2025
The regulation of bone metabolic microenvironment imbalances in diseases such as osteoporosis, defects, infections, and tumors remains a significant challenge orthopedics. Therefore, it has become urgent to develop biomaterials with effective microenvironmental regulatory functions. Zeolites, advanced biomedical materials, possess distinctive physicochemical properties multi-level pore structures, adjustable frameworks, easily modifiable surfaces, excellent adsorption capabilities. These advantageous characteristics give zeolites broad application prospects regulating the microenvironment. this paper first classifies used regulate based on their topological structures compositional frameworks. Subsequently, provides detailed description modification strategies for zeolite materials aimed at Next, comprehensive summary was provided preparation Additionally, focuses specific applications conditions imbalance, orthopedic tumors, highlighting potential enhancing osteogenic microenvironments, controlling treating tumors. Finally, outlines challenges associated This review comprehensively summarizes regulation, aiming provide guidance future research development.
Язык: Английский
Процитировано
0
Journal of Biomaterials Science Polymer Edition, Год журнала: 2025, Номер unknown, С. 1 - 27
Опубликована: Фев. 7, 2025
In orthopaedic clinical applications, creating biocomposite bone substitutes to take the place of autologous transplants is still difficult. Studies have demonstrated for decades that poly (lactic-co-glycolic acid) [PLGA], a common polymer, has many benefits make it strong contender replacement. These include biodegradability, good mechanical qualities, and ability induce new production. Although calcium-based materials are frequently used as fillers in implantation, efficiency ceramic containing calcium may be hampered by number issues, including low microporosity quick rates degradation. order overcome these obstacles, scientists investigating ways improve implant performance combining PLGA with other materials, especially terms encouraging improved connections nearby cells. An overview chemical properties different PLGA-based scaffold composites, well drawbacks PLGA-Calcium implants tissue engineering goals this review. It also highlights possible advantages consequences using 3D printing technology outcomes.
Язык: Английский
Процитировано
0
IntechOpen eBooks, Год журнала: 2025, Номер unknown
Опубликована: Фев. 7, 2025
Biomaterials have experienced significant growth in recent decades. Porous biomaterials demonstrated the ability to create intricate spatial configurations with three dimensions, duplicate physical characteristics of natural tissues, enhance transport large molecular structures and cells through interconnected structures, serve as biologically compatible implants that may or not interact host organism. This section will present a historical perspective on evolution discuss latest advancements production porous biomaterials. The utilization these materials spans wide range clinical applications, along their associated benefits obstacles.
Язык: Английский
Процитировано
0
Journal of Drug Delivery Science and Technology, Год журнала: 2025, Номер 106, С. 106747 - 106747
Опубликована: Фев. 22, 2025
Язык: Английский
Процитировано
0
Biochemical Pharmacology, Год журнала: 2025, Номер unknown, С. 116895 - 116895
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0
Annals of Biomedical Engineering, Год журнала: 2025, Номер unknown
Опубликована: Апрель 3, 2025
Язык: Английский
Процитировано
0
Journal of Biological Engineering, Год журнала: 2025, Номер 19(1)
Опубликована: Май 20, 2025
Despite the natural ability of bone repair, its limitations have led to advanced organic-inorganic-based biomimetic scaffolds and sustained drug release approaches. Particularly, dexamethasone (DEX), a widely used synthetic glucocorticoid, has been shown increase expression bone-related genes during osteogenesis process. This study aims develop hybrid 3D-printed scaffold for controlled delivery dexamethasone. Hence, were fabricated using layer-by-layer 3D-printing combined materials comprising polycaprolactone (PCL)-nanohydroxyapatite (nHA) composite, DEX-loaded PCL microparticles embedded in alginate-gelatin hydrogel. Encapsulation efficiency, loading capacity, vitro kinetics DEX evaluated. Osteogenic differentiation human endometrial mesenchymal stem cells (hEnMSCs) on was assessed by evaluating osteogenic gene levels (collagen I, osteonectin, RUNX2), alkaline phosphatase (ALP) activity, mineralization. The exhibited favorable morphology, mechanical-properties, biocompatibility, biodegradability, enhancing hEnMSCs. within pattern promoted period through significant osteonectin COL1A1 expression. Also, increased mineralization demonstrated SEM alizarin red staining. proposes that drug-loaded organic-inorganic nanocomposite are promising tissue engineering applications.
Язык: Английский
Процитировано
0