Chemical Composition, Antioxidant Potential, and Antimicrobial Activity of Novel Antiseptic Lotion from the Leaves of Betula pendula Roth
Applied Sciences,
Год журнала:
2025,
Номер
15(7), С. 3658 - 3658
Опубликована: Март 26, 2025
Plants
of
the
genus
Betula
pendula
(Betulaceae)
have
been
used
as
antiseptics
in
treatment
skin
diseases.
While
bark
this
plant
has
so
far
a
medicinal
raw
material,
our
research
revealed
that
leaves
are
an
extremely
valuable
source
health-promoting
bioactive
compounds,
especially
polyphenolic
compounds.
The
antioxidant
activity
novel
lotion
from
leaf
and
its
phenolic
content
was
determined
using
DPPH
FRAP
assays
Folin–Ciocalteu
method,
qualitative
analysis
conducted
GC-MS
method.
antiseptic
preparation
also
subjected
to
HPLC
for
assessment
acids
(gallic,
3,4-dihydroxybenzoic,
2,5-dihydroxybenzoic,
chlorogenic,
3-hydroxybenzoic
acids).
shake
flask
method
determine
partition
coefficient
assess
lipophilicity.
A
new
ethanol-reduced
containing
antimicrobial
ingredients
evaluated
standard
killing
methods
(EN
13697:2019
EN
13697:2015)
at
60
±
10
s
300
against
six
microorganisms.
aim
these
tests
whether
formulation
exhibited
performance
like
traditional
ethanol.
In
addition,
hand
disinfection
were
carried
out
obtained
B.
accordance
with
1500:2013,
Escherichia
coli
strain
K12
NCTC
10538.
According
results,
high
polyphenol
contents
(52
2
mg
GAE/g
dry
material)
other
biologically
active
substances
identified
by
(phytol,
alpha-tocospiro
B,
sitosterol,
or
dilauryl
thiodipropionate)
can
be
thought
parameters
responsible
effective
derived
birch
leaves.
Gallic
acid
3,4-dihydroxybenzoic
had
greatest
concentrations
among
examined.
mean
kill
time
>99.9
Staphylococcus
aureus
ATCC
6538
(at
concentration
30
g/100
mL)
Pseudomonas
aeruginosa
15442
40
mL),
while
ethanol
showed
same
reduction
microorganisms
80
mL.
Язык: Английский
Bioactive Potential of Chitosan–Oleic Acid Nanoparticles Loaded with Lemon Peel Essential Oil for Topical Treatment of Vulvovaginal Candidiasis
Molecules,
Год журнала:
2024,
Номер
29(23), С. 5766 - 5766
Опубликована: Дек. 6, 2024
The
rising
incidence
of
vulvovaginal
candidiasis
(VVC)
has
been
leading
to
the
development
alternative
antifungal
therapies.
This
study
aimed
develop
a
topical
chitosan-oleic
acid
nanoparticle
(CH-OA-NP)
cream
loaded
with
lemon
peel
essential
oil
(LPEO)
for
VVC
treatment.
characterization
optimal
formulation
(F4:
10
g/L
CH,
2:1
OA/LPEO
ratio)
showed
high
encapsulation
efficiency,
stability,
and
controlled
release.
Moreover,
it
was
characterized
regarding
its
particle
size,
polydispersity
index,
zeta
potential,
chemical/morphological
profile.
LPEO-related
compounds
(e.g.,
eriodictyol)
were
identified
through
LC-ESI-QqTOF-HRMS
in
matrix,
suggesting
preservation
LPEO
potential
bioactivities
after
formulation.
In
silico
docking
12
metabolites
revealed
that
such
as
citronellic
exerted
inhibitory
effects
against
several
inflammation-associated
enzymes
14-α-Demethylase).
vitro
antimicrobial
tests
demonstrated
remarkable
activity
Язык: Английский
Recovery, Bioactivity, and Utilization of Bioactive Phenolic Compounds in Citrus Peel
Food Science & Nutrition,
Год журнала:
2024,
Номер
12(12), С. 9974 - 9997
Опубликована: Ноя. 7, 2024
ABSTRACT
Citrus
peels
are
rich
in
bioactive
phenolic
compounds
with
various
health
effects
including
antioxidant,
antiobesity,
antiinflammatory,
antihypertensive,
antihypercholesterolemic,
antimicrobial,
antidiabetic,
and
anticarcinogenic
activities.
Both
extractable
nonextractable
phenolics
present
significant
amounts
peel
diverse
bioactivities.
While
can
be
recovered
from
the
fruit
by
conventional
extraction
methods,
remaining
residues
must
released
cell
matrix
first
hydrolysis
acid,
alkali,
or
enzymes.
Novel
processing
technologies
help
improvement
of
efficiency.
Extreme
process
medium
conditions
degrade
their
bioactivity
where
encapsulation
applied
to
improve
stability,
solubility,
bioactivity.
powder
ascorbic
acid
dietary
fiber
besides
extracts
therefrom
used
as
functional
food
ingredients
extend
shelf
life
provide
benefits.
In
addition,
antioxidant
antimicrobial
agents
active
packaging
applications.
Phenolic
have
also
a
potential
nutraceuticals
pharmaceuticals.
this
review,
different
forms
peels,
recovery,
possible
applications
for
upcycling
industry
presented.
Язык: Английский