European Journal of Cancer Care,
Год журнала:
2022,
Номер
31(6)
Опубликована: Сен. 30, 2022
Objective
The
aim
of
this
study
was
to
reach
a
consensus
on
set
proposals
optimise
the
disease
management
Multiple
myeloma
(MM)
within
Spanish
National
Health
System
(SNHS)
and
apply
Social
Return
Investment
(SROI)
method
estimate
their
social
impact.
Methods
A
Multidisciplinary
Working
Team
(MWT)
including
MM
main
stakeholders
organised.
survey
administered
gather
information
from
patients
regarding
impact
different
life
domains.
forecast-type
SROI
analysis,
with
1-year
timeframe,
applied.
Results
Fifteen
were
selected,
management,
actions
for
early
diagnosis,
psychological
support,
improvement
quick
access
palliative
care,
among
others.
implementation
these
would
benefit
patients,
informal
caregivers
SNHS.
investment
required
amount
10.32
million
euros
return
43.31
euros:
4.2
each
euro
invested.
According
sensitivity
ratio
could
range
3.38
5.20
worst
best-case
scenario.
Conclusions
current
be
optimised
by
implementing
that
most
likely
result
in
an
overall
positive
return.
European Journal of Oncology Nursing,
Год журнала:
2024,
Номер
70, С. 102584 - 102584
Опубликована: Апрель 8, 2024
Purpose
Financial
toxicity
(FT)
refers
to
the
subjective
perception
of
financial
distress
resulting
from
objective
economic
strain
due
illness,
exerting
a
detrimental
influence
on
health
outcomes.
This
study
aimed
describe
FT
among
allogeneic
haematopoietic
stem
cell
transplant
(allo-HSCT)
recipients
within
public
framework,
employing
social
determinants
approach.
Methods
A
multi-centre
cross-sectional
involving
adult
allo-HSCT
patients
was
conducted
across
three
hospitals
in
Madrid.
assessed
using
validated
COST
scale
(range
0–44;
lower
scores
indicating
higher
FT).
Patient-administered
paper/online
questionnaires
were
utilized
collect
data
sociodemographic,
socioeconomic,
clinical,
and
healthcare
access
variables.
Descriptive,
non-parametric
univariate
statistical
analysis
multiple
linear
regression
models
performed.
Results
Sixty-six
patients,
with
mean
age:
52.5
years
(SD:
11.5),
50%
women,
28.7%
displaced
Madrid
for
HSCT,
71.4%
lacking
support
included.
The
median
score
20
points
(IQR
12–27.25).
Independent
factors
associated
included
being
females
(Coef
=
−3.26;
p
0.079),
perceived
income
loss
after
HSCT
−6.81;
<
0.001)
monthly
household
≤1000
€
compared
1001–2500€
8.29;
0.005)
or
>2500
15.75;
0.001).
Conclusions
Despite
limited
sample
size,
our
findings
underscore
presence
shaped
by
health.
Recognizing
addressing
process
is
essential
mitigate
inequalities
Heliyon,
Год журнала:
2024,
Номер
10(11), С. e31948 - e31948
Опубликована: Май 24, 2024
PurposeThis
study
aims
to
identify
the
key
factors
influencing
health-related
quality
of
life
(HRQoL)
pediatric
acute
myeloid
leukemia
(AML)
patients
following
their
initial
diagnosis
and
examine
impact
on
five-year
survival
prognosis.MethodsA
chart
review
follow-up
were
conducted
for
children
with
AML
who
participated
in
a
prospective
cohort
between
2017
2020.
We
identified
HRQoL
through
Pediatric
Quality
Life
Inventory™
(PedsQL™
4.0),
PedsQL™
Cancer
Module
3.0
(CM
3.0)
Family
Impact
2.0
(FIM
2.0),
as
well
assessed
impaired
overall
outcomes
patients.ResultsSixty-four
subjects
enrolled
had
complete
outcome
data,
61
them
completed
5-year
follow-up.
In
CM
3.0,
age
was
positively
associated
parental
proxy
reports
(p
=
0.040),
whereas
divorced
families
negatively
child
self-reports
0.045).
A
positive
medical
history
correlates
FIM
0.025).
Residence
0.046),
occupation
caregivers
0.014),
disease
severity
0.024),
only
0.029)
exhibited
statistically
significant
associations
impairment
HRQoL.
Impaired
scores
shown
by
PedsQL™4.0
parent
report
0.013)
0.011)
reduced
rate.ConclusionsThis
demonstrated
that
early
has
predictive
value
long-term
prognosis.
Once
validated,
these
findings
may
provide
some
guidance
clinicians
treating
AML.
Authorea (Authorea),
Год журнала:
2023,
Номер
unknown
Опубликована: Март 2, 2023
Background
While
racial
disparities
in
the
clinical
outcomes
of
hematopoietic
stem
cell
transplant
(HSCT)
patients
have
been
explored,
quality
life
(QoL)
during
readjustment
phase
after
has
yet
to
be
investigated
pediatric
patients.
The
objective
this
study
was
examine
role
patient
race
QoL
at
least
two
years
HSCT.
Procedure
We
conducted
a
retrospective
chart
review
under
21
age
diagnosis
that
received
an
allogeneic
our
institution
between
January
2007
and
December
2017.
Patient
assessed
using
PedsQL
TM
4.0
post-transplant.
demographic,
treatment,
outcome
data
were
obtained
for
subsequent
analysis,
where
categorized
as
either
Black,
White,
Hispanic,
or
Native
American.
Results
Data
collected
on
86
who
underwent
Forty
(46.5%)
non-Hispanic
29
(33.7%)
10
(11.6%)
7
(8.1%)
Where
preliminary
analyses
indicated
difference
by
race,
there
no
significant
differences
physical,
emotional,
social,
school
functioning
adjusting
characteristics
(age
transplant,
sex,
diagnosis,
donor
type
conditioning
regimen)
determinants
socioeconomic
status
(insurance
type,
estimated
household
income).
Conclusions
Pediatric
had
comparable
QoL,
regardless
median
three
HSCT
cohort.
Pediatric Blood & Cancer,
Год журнала:
2023,
Номер
70(9)
Опубликована: Июнь 19, 2023
While
racial
disparities
in
the
clinical
outcomes
of
hematopoietic
stem
cell
transplant
(HSCT)
patients
have
been
explored,
quality
life
(QoL)
during
re-adjustment
phase
after
are
yet
to
be
investigated
pediatric
patients.
The
objective
this
study
was
examine
role
patient
race
QoL
at
least
2
years
HSCT.We
conducted
a
retrospective
chart
review
under
21
age
diagnosis
who
received
an
allogeneic
our
institution
between
January
2007
and
December
2017.
Patient
assessed
using
Pediatric
Quality-of-Life
Inventory
Generic
Score
Scales
(PedsQL
TM
4.0)
post
transplant.
demographic,
treatment,
outcome
data
were
obtained
for
subsequent
analysis,
where
categorized
as
either
Black,
White,
Hispanic,
or
Native
American.Data
collected
on
86
underwent
HSCT.
Forty
(46.5%)
non-Hispanic
29
(33.7%)
10
(11.6%)
seven
(8.1%)
American.
Where
preliminary
analyses
indicated
difference
by
race,
there
no
significant
differences
physical,
emotional,
social,
school
functioning
adjusting
characteristics
(age
transplant,
sex,
diagnosis,
donor
type,
conditioning
regimen)
determinants
socioeconomic
status
(insurance
estimated
household
income).Pediatric
had
comparable
QoL,
regardless
median
3
HSCT
cohort.
European Journal of Cancer Care,
Год журнала:
2022,
Номер
31(6)
Опубликована: Сен. 30, 2022
Objective
The
aim
of
this
study
was
to
reach
a
consensus
on
set
proposals
optimise
the
disease
management
Multiple
myeloma
(MM)
within
Spanish
National
Health
System
(SNHS)
and
apply
Social
Return
Investment
(SROI)
method
estimate
their
social
impact.
Methods
A
Multidisciplinary
Working
Team
(MWT)
including
MM
main
stakeholders
organised.
survey
administered
gather
information
from
patients
regarding
impact
different
life
domains.
forecast-type
SROI
analysis,
with
1-year
timeframe,
applied.
Results
Fifteen
were
selected,
management,
actions
for
early
diagnosis,
psychological
support,
improvement
quick
access
palliative
care,
among
others.
implementation
these
would
benefit
patients,
informal
caregivers
SNHS.
investment
required
amount
10.32
million
euros
return
43.31
euros:
4.2
each
euro
invested.
According
sensitivity
ratio
could
range
3.38
5.20
worst
best-case
scenario.
Conclusions
current
be
optimised
by
implementing
that
most
likely
result
in
an
overall
positive
return.
