Advancing Non-Invasive Diagnosis of Oral Epithelial Dysplasia: Comparative Insights from In Vivo Optical Coherence Tomography and Histopathology
Journal of Clinical Medicine,
Год журнала:
2025,
Номер
14(4), С. 1118 - 1118
Опубликована: Фев. 9, 2025
Background:
Oral
epithelial
dysplasia
(OED)
is
considered
one
of
the
premalignant
lesions
for
oral
squamous
cell
carcinoma
(OSCC),
which
five-year
disease-free
survival
rate
may
vary
widely.
There
has
emerged
in
recent
years,
therefore,
a
significant
niche
optical
coherence
tomography
(OCT)
to
non-invasively
examine
tissue
morphology.
The
present
study
was
conducted
evaluate
diagnostic
performance
OCT
distinguishing
between
mild,
moderate,
and
severe
dysplasias
situ
(CIS)
with
histopathological
correlations.
Methods:
This
prospective,
single-centre
included
120
patients
clinically
suspicious
lesions.
All
underwent
vivo
imaging
followed
by
surgical
excision
examination.
sensitivity,
specificity,
AUC
(area
under
curve)
were
calculated
as
measures
accuracy.
Results:
demonstrated
high
sensitivity
specificity
above
80%
all
grades
dysplasia.
values
highest
moderate
at
0.91
mild
0.89.
Bland–Altman
analysis
revealed
degree
agreement
histopathology
regarding
tumour
depth
measurements.
Interobserver
substantial
almost
perfect,
kappa
ranging
from
0.74
0.85.
provided
key
features
thickening,
basement
membrane
disruption,
architectural
disorganization.
These
had
good
correlations
grade
dysplasia:
r
=
0.75–0.82,
p
<
0.001.
Conclusions:
an
established
technique
that
non-invasive
nature
diagnosis
OED;
it
can
provide
fine
differentiation
among
define
margins
lesion.
Язык: Английский
Inter-disciplinary Gap between Medicine and Dentistry: Referral Pattern, and Attitude of Physicians towards Oral Medicine in Yazd Province
Journal of Research in Dental and Maxillofacial Sciences,
Год журнала:
2025,
Номер
10(1), С. 59 - 67
Опубликована: Март 1, 2025
Язык: Английский
Community-Based Telehealth Approach Improves Specialist Access for Individuals with Increased Cancer Risk in Low-Resource Settings
Cancers,
Год журнала:
2025,
Номер
17(8), С. 1317 - 1317
Опубликована: Апрель 14, 2025
Background/Objectives:
The
low-resource,
minority
and
underserved
populations
(LRMU)
that
carry
the
highest
risk
of
oral
cancer
(OC)
experience
many
barriers
to
early
detection
treatment,
resulting
in
disproportionately
poor
outcomes.
One
major
barrier
better
outcomes
is
compliance
with
specialist
referral
for
diagnosis
treatment.
goal
this
prospective
study
was
compare
Telehealth
vs.
in-person
visits
LRMU
individuals
screening
positive
increased
OC
risk.
Methods:
Forty
subjects
who
had
screened
potentially
malignant
lesions
(OPMLs)
were
recruited
from
community
clinics.
indicated
whether
they
would
prefer
an
or
visit.
They
offered
assistance
all
aspects
visit,
then
tracked
over
3
months
compliance.
A
novel,
very
low-cost,
simple
platform
located
within
clinic
used
remote
visits.
Results:
In
group,
16/24
attended
their
first
scheduled
visit;
4/24
rescheduled
months,
did
not
comply
at
all.
All
attendees
specialists
able
complete
full.
Of
7/16
completed
visits,
3/16
4/16
complied
months;
9/16
referral.
Significantly
more
1
month
(p
=
0.0006)
after
0.0154).
Conclusions:
This
novel
may
improve
low-resource
OPMLs.
Язык: Английский
Inter-observer agreement among specialists in the diagnosis of oral potentially malignant disorders and oral cancer using store-and-forward technology
Clinical Oral Investigations,
Год журнала:
2023,
Номер
27(12), С. 7575 - 7581
Опубликована: Окт. 23, 2023
Язык: Английский
Compliance with Specialist Referral for Increased Cancer Risk in Low-Resource Settings: In-Person vs. Telehealth Options
Cancers,
Год журнала:
2023,
Номер
15(10), С. 2775 - 2775
Опубликована: Май 16, 2023
Efforts
are
underway
to
improve
the
accuracy
of
non-specialist
screening
for
oral
cancer
(OC)
risk,
yet
better
will
only
translate
into
improved
outcomes
if
at-risk
individuals
comply
with
specialist
referral.
Most
from
low-resource,
minority,
and
underserved
(LRMU)
populations
fail
complete
a
referral
OC
risk.
The
goal
was
evaluate
impact
novel
approach
on
compliance
in
positive
risk
outcome.
A
total
60
LRMU
subjects
who
had
screened
increased
were
recruited
given
choice
an
in-person
(20
subjects)
or
telehealth
(40
visit.
Referral
tracked
weekly
over
6
months.
Compliance
30%
group,
83%
group.
Approximately
83–85%
both
groups
complied
first
second
follow-up
Overall,
72.5%
chosen
remote
visit
entered
continuum
care
by
study
end,
vs.
25%
two-step
that
uses
overcome
barriers
may
Язык: Английский
Digital Behavior Change Interventions along Cancer Prevention, Education, and Screening Promotion among Latina(o) Adults: A Systematic Review of the Literature (Preprint)
Опубликована: Апрель 29, 2024
BACKGROUND
Cancer
health
disparities
in
Latina(o)
populations
stem
from
economic,
cultural,
linguistic,
and
systemic
barriers,
which
simultaneously
hinder
effective
screening
early
detection,
directly
contribute
to
lower
rates.
Fear,
stigma,
challenges
navigating
the
healthcare
system
exacerbate
this
issue,
underscoring
urgent
need
for
initiatives
aimed
at
increasing
cancer
rates
population
enable
earlier
identification
treatment
of
cases.
Digital
behavior
change
interventions
(DBCIs)
offer
accessible,
cost-effective
methods
increase
affect
outcomes
communities.
Despite
their
potential,
research
on
DBCIs'
specific
impacts
prevention,
education,
promotion
among
Hispanic/Latina(o)
remains
sparse
.
In
our
review,
we
use
"Latina(o)"
reflect
community's
preferences,
as
highlighted
by
recent
studies,
"Hispanic"
broader
Spanish-speaking
groups,
ensuring
language
is
inclusive
sensitive
diverse
identities.
OBJECTIVE
This
systematic
spanning
January
2000
–
March
2023,
aims
characterize
existing
literature
findings
impact
digital
screening,
education
populations.
It
critically
evaluates
designs,
participant
demographics,
intervention
components,
technological
platforms,
cultural
tailoring,
measured
included
studies.
METHODS
Adhering
PRISMA
PICOS
,
review
focused
English
Spanish
articles
that
specifically
address
DBCIs
aged
18-75
excluding
non-interventional
qualitative
We
implemented
a
robust
search
strategy
across
databases:
PubMed,
Embase,
ERIC,
PsycINFO,
Scopus,
Web
Science,
CINAHL.
Data
were
extracted,
abstracted,
synthesized
comprehensive
analysis
present
evidence.
RESULTS
The
analyzed
22
1,884
Most,
95%
(21/22)
US-centric
with
clinical
settings
common
41%
(9/22)
alongside
online
community
settings.
Study
design
68%
(15/22)
randomized
controlled
trials
32%
(7/22)
quasi-experimental.
About
55%
(12/22)
exclusively
Latina(o)s,
72%
(16/22)
not
specifying
race,
country
origin
or
subgroups.
led
linguistic
adjustments
encompassed
yet
only
40%
went
beyond
baseline
surveys,
literacy
adaptations,
linguistics
integrate
values.
45%
(10/22)
used
smartphones
promote
screenings.
Of
these
70%
(7/10)
improving
rates,
notably
breast
(75%,
3/4)
colorectal
(100%,
3/3)
cancers;
there
was
mixed
results
cervical.
studies
constituted
overall
all
had
positive
impact.
A
Majority
these,
71%
(5/7),
utilized
delivery,
cancer,
86%
(6/7).
smaller
portion
addressed
melanoma
14%
(1/7),
employing
apps
designed
symptom
management
lifestyle
advice.
prevention
comprised
23%
(5/22)
studies;
(2/5)
outcomes.
Specifically,
20%
(1/5)
smartphone
texting
HPV
vaccine
uptake,
employed
web
platform
cervical
information-seeking.
CONCLUSIONS
significant
opportunity
addressing
U.S.
communities,
however,
effectiveness
requires
more
than
changes;
adaptations
are
crucial.
While
adjusted
language,
incorporated
culture,
highlighting
culturally
nuanced
interventions.
strategies
improved
CRCS
although
indicate
potential
further
improvement.
utilizing
increased
awareness,
mobile
technology's
information
dissemination.
Yet,
should
expand
cover
CRC,
using
tools
guidance.
showed
limited
success
vaccination
information-seeking
enhanced
DBCI
greater
future
deeper
align
values
beliefs
evident.
Focusing
accessible
technology,
especially
apps,
crucial
enhancing
equitable
Язык: Английский
Inter-observer agreement among specialists in the diagnosis of Oral Potentially Malignant Disorders and Oral Cancer using Store-and-Forward technology
Research Square (Research Square),
Год журнала:
2023,
Номер
unknown
Опубликована: Апрель 5, 2023
Oral
Cancer
is
one
of
the
most
common
causes
morbidity
and
mortality.
Screening
mobile
Health
(mHealth)
based
approach
facilitates
remote
early
detection
cancer
in
a
resource-constrained
settings.
The
emerging
eHealth
technology
has
aided
specialist
reach
to
rural
areas
enabling
monitoring
triaging
downstage
cancer.
Though
diagnostic
accuracy
been
evaluated,
there
are
no
studies
evaluating
consistency
among
specialists,
best
our
knowledge.
purpose
study
was
evaluate
interobserver
agreement
between
specialists
through
telemedicine
systems
real-world
settings
using
store
forward
technology.
Two
independently
diagnosed
clinical
images
from
image
repositories,
compared
with
onsite
histopathological
diagnosis
when
available.
Moderate
(k
=
0.682)
two
0.629)
diagnosing
oral
lesions.
sensitivity
specificity
1
were
92.7%
83.3%,
whereas
2
95.8%
60%,
respectively,
histopathology.
telecare
can
be
effective
tools
surveillance
patients.
Язык: Английский