When Pulmonologists Are Novice to Navigational Bronchoscopy, What Predicts Diagnostic Yield? DOI Creative Commons
Louise Lindhardt Toennesen,

Helene Hjorth Vindum,

Ellen Risom

и другие.

Diagnostics, Год журнала: 2022, Номер 12(12), С. 3127 - 3127

Опубликована: Дек. 12, 2022

Predicting factors of diagnostic yield in electromagnetic navigation bronchoscopy (ENB) have been explored a number previous studies based on data from experienced operators. However, little is known about predicting when the procedure carried out by operators beginning their learning curve. We here aim to identify role operators’ experience as well lesion– and characteristics ENB procedures hands novice Four three centers without prior were enrolled. The outcome consecutive was assessed classified either or non-diagnostic assessed. A total 215 122 (57%) resulted biopsies. Diagnostic associated with minor yet significant difference tumor size compared non-diagnostic/inconclusive (28 mm vs. 24 mm; p = 0.03). visible lesions at fluoroscopy (p 0.003) radial endobronchial ultrasound (rEBUS), 0.001). In logistic regression model, lesion visibility fluoroscopy, but none operator experience, presence bronchus sign, size, location nor rEBUS significantly impacted yield. operators, only factor found increase chance obtaining sample.

Язык: Английский

High-Sensitivity Graphene-Gold Metasurface Optical Biosensor for Early Melanoma Detection Optimized with Machine Learning Using a One-Dimensional Convolutional Neural Network and Binary Encoding DOI
Jacob Wekalao, Ahmed Mehaney,

Nassir Saad Alarifi

и другие.

Physica E Low-dimensional Systems and Nanostructures, Год журнала: 2025, Номер unknown, С. 116214 - 116214

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

7
Transbronchial lung cryobiopsy for peripheral pulmonary lesions. A narrative review DOI Creative Commons
Yibo Tang, Sen Tian, Hua Chen

и другие.

Pulmonology, Год журнала: 2023, Номер 30(5), С. 475 - 484

Опубликована: Окт. 31, 2023

An increasing number of peripheral pulmonary lesions (PPLs) requiring tissue verification to establish a definite diagnosis for further individualized management are detected due the growing adoption lung cancer screening by chest computed tomography (CT), especially low-dose CT. However, morphological PPLs remains challenging. Transbronchial cryobiopsy (TBLC) that can retrieve larger specimens with more preserved cellular architecture and fewer crush artifacts in comparison conventional transbronchial forceps biopsy (TBFB), as an emerging technology diagnosing PPLs, has been demonstrated have potential resolve clinical dilemma pertaining currently available sampling devices (e.g., forceps, needle brush) become diagnostic cornerstone PPLs. Of note, introduction 1.1 mm cryoprobe will be compatible advanced bronchoscopic navigation techniques, such radial endobronchial ultrasound (r-EBUS), virtual (VBN) electromagnetic bronchoscopy (ENB), use TBLC is expected gain popularity While much exploration using technique it envisaged emergence additional studies data accrual hopefully add body evidence this field.

Язык: Английский

Процитировано

11
Design and Simulation of a Continuous Robotic Arm Assisted by Neuroendoscopic Surgery DOI Creative Commons

宇 张

Modeling and Simulation, Год журнала: 2025, Номер 14(01), С. 251 - 266

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
A review on diagnostic assessments of tracheal stenosis DOI Creative Commons
Mojdeh Monjezi, Milad Rismanian, Hamidreza Jamaati

и другие.

BioMedical Engineering OnLine, Год журнала: 2025, Номер 24(1)

Опубликована: Фев. 14, 2025

Язык: Английский

Процитировано

0
A new paradigm of e-NOSE technology for the non-invasive and early lung cancer diagnostics DOI

Ashok Saini,

Neelam Yadav

Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 162155 - 162155

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0
Enhancing Lung Cancer Care in Portugal: Bridging Gaps for Improved Patient Outcomes DOI Open Access
Raquel Ramos,

Conceição Souto Moura,

Mariana Fernandes Costa

и другие.

Journal of Personalized Medicine, Год журнала: 2024, Номер 14(5), С. 446 - 446

Опубликована: Апрель 24, 2024

Lung cancer has the highest incidence and cancer-related mortality worldwide. In Portugal, it ranks as fourth most common cancer, with nearly 6000 new cases being diagnosed every year. is main cause of death among males third in females. Despite globally accepted guidelines recommendations for what would be ideal path a lung patient, several challenges occur real clinical management across world. The emphasize importance adequate screening high-risk individuals, precise tumour biopsy, an accurate final diagnosis to confirm neoplastic nature nodule. A detailed histological classification type comprehensive molecular characterization are utmost selection efficacious patient-directed therapeutic approach. However, context Portuguese organization national healthcare system, there still gaps pathway involving aspects ranging from absence programme through difficulties approaches. this manuscript, we address relevant weaknesses, presenting proposals potential solutions improve patients, helping decisively their overall survival quality life.

Язык: Английский

Процитировано

2
Cone-beam computed tomography-guided endobronchial ultrasound using an ultrathin bronchoscope for diagnosis of peripheral pulmonary lesions: a prospective pilot study DOI Open Access
Naoya Kawakita,

Hiroaki Toba,

Shinichi Sakamoto

и другие.

Journal of Thoracic Disease, Год журнала: 2023, Номер 15(2), С. 579 - 588

Опубликована: Фев. 1, 2023

Background: Multimodal transbronchial biopsy (TBB) may have improved diagnostic yield for peripheral pulmonary lesions suspected as lung cancer. Radial endobronchial ultrasound (R-EBUS) provides real-time imaging and confirmation of the location lesions. Cone-beam computed tomography (CBCT) can confirm that forceps tip has reached lesion before biopsy. Methods: Patients with a positive (CT) bronchus sign (based on slice thickness 1 mm) were prospectively enrolled. An ultrathin bronchoscope (UTB) R-EBUS probe advanced to target bronchus. Thereafter, advanced, CBCT was performed. performed re-navigation, if possible. The obtained EBUS images classified into "within" (type 1), "adjacent to" 2), or "far from" 3), based tip. Results: For 20 lesions, 85%. primary types 1, 2, 3 in 12, 6, 2 cases, respectively. Primary image equivalent 14 cases. Of 12 cases type image, 9 had while exhibited positional misalignment Re-navigation required 8 images. Conclusions: CBCT-guided TBB using an UTB enable positioning guidance better re-navigation diagnosis

Язык: Английский

Процитировано

6
Comparative analysis of the efficacy and safety of electromagnetic navigation bronchoscopy combined with x‐ray or radial endobronchial ultrasound biopsy in the diagnosis of small peripheral pulmonary nodules DOI Creative Commons
Yifan Fu,

Xin-Yu Yuan,

Wenyin Pan

и другие.

Thoracic Cancer, Год журнала: 2023, Номер 14(15), С. 1348 - 1354

Опубликована: Апрель 10, 2023

Abstract Objective To compare the clinical value and safety of electromagnetic navigation bronchoscopy (ENB) combined with radial endobronchial ultrasound (R‐EBUS) or x‐ray in diagnosis small peripheral pulmonary nodules that cannot be diagnosed by conventional bronchoscopy. Methods Fifty‐six patients <3 cm diameter who underwent at First Affiliated Hospital Soochow University Dushu Lake from February 2019 to January 2022 were selected as study subjects, including 24 ENB 32 R‐EBUS. was used guiding method both groups, group R‐EBUS R‐EBUS, respectively, determine whether lesion reached. In group, biopsy brushing performed under fluoroscopic guidance. Using results surgery, puncture pathology, follow‐up 1 year gold standard, diagnostic sensitivity, specificity, negative predictive (NPV), yield, likelihood ratio (LR‐), Youden index, missed rate, success κ compared between two occurrence postoperative complications also groups. Results The significantly better than ( p = 0.006). Conclusion Even smaller nodule diameters, still higher group.

Язык: Английский

Процитировано

5
Prospect of large language models and natural language processing for lung cancer diagnosis: A systematic review DOI

Arushi Garg,

Smridhi Gupta,

Soumya Vats

и другие.

Expert Systems, Год журнала: 2024, Номер 41(11)

Опубликована: Авг. 15, 2024

Abstract Lung cancer, a leading cause of global mortality, demands combat for its effective prevention, early diagnosis, and advanced treatment methods. Traditional diagnostic methods face limitations in accuracy efficiency, necessitating innovative solutions. Large Language Models (LLMs) Natural Processing (NLP) offer promising avenues overcoming these challenges by providing comprehensive insights into medical data personalizing plans. This systematic review explores the transformative potential LLMs NLP automating lung cancer diagnosis. It evaluates their applications, particularly imaging interpretation complex data, assesses achievements associated challenges. Emphasizing critical role Artificial Intelligence (AI) imaging, highlights advancements screening deep learning approaches. Furthermore, it underscores importance on‐going encourages further exploration this field.

Язык: Английский

Процитировано

1
The diagnostic performance and optimal strategy of cone beam CT-assisted bronchoscopy for peripheral pulmonary lesions: A systematic review and meta-analysis DOI Creative Commons

Huijie Yang,

Junfeng Huang, Yu Zhang

и другие.

Pulmonology, Год журнала: 2024, Номер 31(1)

Опубликована: Ноя. 4, 2024

Cone-beam computed tomography (CBCT) assisted bronchoscopy shows prospective advantages in diagnosing peripheral pulmonary lesions (PPLs), but its diagnostic value and potential influencing factors remain unclear. What is the clinical optimal strategy of CBCT-assisted PPLs? The references were searched from PubMed, EmBase, Web Science. Studies reporting yield included. navigational success rate, complication pooled by random-effects model meta-regression. A total 1,441 patients with 1,540 15 studies included our meta-analysis. rate (97.0% vs 81.6%; odds ratio [OR] 5.12) (78.5% 55.7%; OR 2.51) group significantly higher than those without CBCT. was 4.4% (95%CI: 0.02-0.07). CT combined r-EBUS can achieve highest rate. Applying positive end-expiratory pressure could improve reduce (p < 0.05). Lesions located upper lobe a right lobes get lower seems to be effective approach ameliorate navigation PPLs.Clinical trial registration: This study registered PROSPERO (Registration Number: CRD42022378992). URL: (york.ac.uk).

Язык: Английский

Процитировано

1