Role of Vaccination Strategies to Host-Pathogen Dynamics in Social Interactions DOI Creative Commons
Marlon Nunes Gonzaga, Marcelo Martins de Oliveira, A. P. F. Atman

и другие.

Entropy, Год журнала: 2024, Номер 26(9), С. 739 - 739

Опубликована: Авг. 30, 2024

This study presents extended Immunity Agent-Based Model (IABM) simulations to evaluate vaccination strategies in controlling the spread of infectious diseases. The application IABM analysis configurations is innovative, as a vaccinated individual can be infected depending on how their immune system acts against invading pathogen, without pre-established infection rate. Analysis at microscopic level demonstrates impact responses and outcomes, providing more realistic representation humoral response caused by affects individual's defense. At macroscopic level, effects different population-wide are explored, including random vaccination, targeted specific demographic groups, spatially focused vaccination. results indicate that increased rates correlated with decreased mortality rates, highlighting importance achieving herd immunity. Furthermore, vulnerable populations or densely populated regions prove effective reducing disease transmission compared randomly distributed presented this work show highly crowded efficient epidemics outbreaks. Results suggest applying only densest region resulted suppression region, less intense viral areas lower population densities. Strategies regions, addition being number dead people, reduce costs related transportation, storage, distribution doses strategy. Considering that, despite scientific efforts consolidate use mass accessibility, affordability, acceptability vaccines problems persist, investing mitigate such issues crucial development government policies make immunization systems robust.

Язык: Английский

Transitioning from Host-Pathogen Dynamics to Social Interactions: Assessing Vaccination Strategies through the IABM Model DOI Open Access
Marlon Nunes Gonzaga, Marcelo Martins de Oliveira, A. P. F. Atman

и другие.

Опубликована: Июль 9, 2024

This study presents extended Immunity Agent-Based Model (IABM) simulations to evaluate vaccination strategies in controlling the spread of infectious diseases. The application IABM analysis configurations is innovative, as a vaccinated individual can be infected depending on how their immune system acts against invading pathogen, without pre-established infection rate. Analysis at microscopic level demonstrates impact responses and outcomes, providing more realistic representation humoral response caused by affects individual’s defense. At macroscopic level, effects different population-wide are explored, including random vaccination, targeted specific demographic groups, spatially focused vaccination. results indicate that increased rates correlated with decreased mortality rates, highlighting importance achieving herd immunity. Furthermore, vulnerable populations or densely populated regions prove effective reducing disease transmission compared randomly distributed presented this work show highly crowded efficient epidemics outbreaks. Results suggest applying only densest region resulted suppression region, less intense viral areas lower population densities. Strategies regions, addition being number dead people, reduce costs related transportation, storage, distribution doses strategy. Considering that, despite scientific efforts consolidate use mass accessibility, affordability, acceptability vaccines problems persist, investing mitigate such issues crucial development government policies make immunization systems robust.

Язык: Английский

Процитировано

0
Role of Vaccination Strategies to Host-Pathogen Dynamics in Social Interactions DOI Creative Commons
Marlon Nunes Gonzaga, Marcelo Martins de Oliveira, A. P. F. Atman

и другие.

Entropy, Год журнала: 2024, Номер 26(9), С. 739 - 739

Опубликована: Авг. 30, 2024

This study presents extended Immunity Agent-Based Model (IABM) simulations to evaluate vaccination strategies in controlling the spread of infectious diseases. The application IABM analysis configurations is innovative, as a vaccinated individual can be infected depending on how their immune system acts against invading pathogen, without pre-established infection rate. Analysis at microscopic level demonstrates impact responses and outcomes, providing more realistic representation humoral response caused by affects individual's defense. At macroscopic level, effects different population-wide are explored, including random vaccination, targeted specific demographic groups, spatially focused vaccination. results indicate that increased rates correlated with decreased mortality rates, highlighting importance achieving herd immunity. Furthermore, vulnerable populations or densely populated regions prove effective reducing disease transmission compared randomly distributed presented this work show highly crowded efficient epidemics outbreaks. Results suggest applying only densest region resulted suppression region, less intense viral areas lower population densities. Strategies regions, addition being number dead people, reduce costs related transportation, storage, distribution doses strategy. Considering that, despite scientific efforts consolidate use mass accessibility, affordability, acceptability vaccines problems persist, investing mitigate such issues crucial development government policies make immunization systems robust.

Язык: Английский

Процитировано

0